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SP1 antibody (C-Term)
SP1
Reactivity: Human
WB, IF, IHC (p), FACS, EIA
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-SP1 Antibody
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Target
See all SP1 Antibodies
SP1
(Sp1 Transcription Factor (SP1))
Binding Specificity
All epitopes for SP1 antibodies
AA 684-715, C-Term
Reactivity
All reactivities for SP1 antibodies
Human
Host
All hosts for SP1 antibodies
Rabbit
Clonality
All clonalities for SP1 antibodies
Polyclonal
Conjugate
All conjugates for SP1 antibodies
This SP1 antibody is un-conjugated
Application
All applications for SP1 antibodies
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)
Specificity
This antibody recognizes SP1 / TSFP1 at C-term.
Cross-Reactivity (Details)
Species reactivity (tested):Human
Purification
Purified through a Protein A column followed by peptide affinity purification
Immunogen
Synthetic peptide - KLH conjugated - corresponding to the C-terminal region (between 684-715aa) of human SP1 / TSFP1
Isotype
Ig Fraction
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
0.25 mg/mL
Buffer
PBS with 0.09 % (W/V) Sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target Details for SP1
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Target
SP1
(Sp1 Transcription Factor (SP1))
Abstract
SP1 Products
Synonyms
fc18h09 antibody, zgc:85950 antibody, wu:fc18h09 antibody, SP1 antibody, 1110003E12Rik antibody, AA450830 antibody, AI845540 antibody, Sp1-1 antibody, sp1 transcription factor antibody, Sp1 transcription factor antibody, Sp1 transcription factor L homeolog antibody, trans-acting transcription factor 1 antibody, sp1 antibody, SP1 antibody, Sp1 antibody, sp1.L antibody
Background
Transcription factor that can activate or repress transcription in response to physiological and pathological stimuli. Binds with high affinity to GC-rich motifs and regulates the expression of a large number of genes involved in a variety of processes such as cell growth, apoptosis, differentiation and immune responses. Highly regulated by post-translational modifications (phosphorylations, sumoylation, proteolytic cleavage, glycosylation and acetylation). Binds also the PDGFR-alpha G-box promoter. May have a role in modulating the cellular response to DNA damage. Implicated in chromatin remodeling. Plays a role in the recruitment of SMARCA4/BRG1 on the c-FOS promoter. Plays an essential role in the regulation of FE65 gene expression.Synonyms: Transcription factor Sp1
Gene ID
6667
NCBI Accession
NP_003100
Pathways
Regulation of Lipid Metabolism by PPARalpha , Myometrial Relaxation and Contraction
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