SPON2 antibody (Internal Region)

Catalog No. ABIN954937

Product Details anti-SPON2 Antibody

Target: SPON2 (Spondin 2 (SPON2))

Binding Specificity: AA 301-315, Internal Region

Reactivity: Human, Mouse, Rat, Dog

Host: Goat

Clonality: Polyclonal

Conjugate: This SPON2 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Sequence: C-RTRYVRVQPA NNGSP Remarks: Reported variants represent identical protein: NP_036577.1, NP_001121797.1, NP_001185950.1

Specificity: Recognizes SPON2 (301-315).

Cross-Reactivity (Details): Species reactivity (expected):Mouse, Rat, Dog.
Species reactivity (tested):Human.

Purification: Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide

Immunogen: Peptide with sequence from the internal region (near C Terminus) of the protein sequence according to NP_036577.1. Genename: SPON2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Tris buffered saline, pH ~7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for SPON2

Target: SPON2 (Spondin 2 (SPON2))

Alternative Name: Spondin 2 / SPON2 (SPON2 Products)

Synonyms: DIL-1 antibody, DIL1 antibody, M-SPONDIN antibody, MINDIN antibody, 2310045I24Rik antibody, AI504350 antibody, M-spondin antibody, Mindin antibody, Mspondin antibody, etID309958.14 antibody, mindin2 antibody, zgc:100756 antibody, mindin1 antibody, spondin 2 antibody, spondin 2, extracellular matrix protein antibody, spondin 2, extracellular matrix protein S homeolog antibody, spondin 2b, extracellular matrix protein antibody, spondin 2a, extracellular matrix protein antibody, SPON2 antibody, Spon2 antibody, spon2.S antibody, spon2b antibody, spon2a antibody

Background: Spondin-2 (SPON2) is a cell adhesion protein which promotes adhesion and outgrowth of hippocampal embryonic neurons. It binds directly to bacteria and their components and functions as an opsonin for macrophage phagocytosis of bacteria. SPON2 is essential in the initiation of the innate immune response and represents a unique pattern-recognition molecule in the ECM for microbial pathogens.Synonyms: DIL-1, DIL1, Differentially expressed in cancerous and non-cancerous lung cells 1, M-spondin, Mindin, Spondin-2

Gene ID: 10417

NCBI Accession: NP_001121797