TBX3 antibody (Middle Region)

Catalog No. ABIN955111

Product Details anti-TBX3 Antibody

Target: TBX3 (T-Box 3 (TBX3))

Binding Specificity: AA 309-338, Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TBX3 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody reacts to TBX3.

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Affinity chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 309-338 amino acids from the Central region of human TBX3

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for TBX3

Target: TBX3 (T-Box 3 (TBX3))

Alternative Name: TBX3 (TBX3 Products)

Synonyms: xtbx3 antibody, ums antibody, xhl antibody, tbx3-iso antibody, TBX3 antibody, TBX3-ISO antibody, UMS antibody, XHL antibody, D5Ertd189e antibody, T-box 3 antibody, T-box 3 S homeolog antibody, TBX3 antibody, tbx3.S antibody, tbx3 antibody, Tbx3 antibody

Background: This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This protein is a transcriptional repressor and is thought to play a role in the anterior/posterior axis of the tetrapod forelimb. Mutations in this gene cause ulnar-mammary syndrome, affecting limb, apocrine gland, tooth, hair, and genital development. Alternative splicing of this gene results in three transcript variants encoding different isoforms, however, the full length nature of one variant has not been determined.Synonyms: T-box protein 3, T-box transcription factor TBX3

Molecular Weight: 79389 Da

Gene ID: 6926

NCBI Accession: NP_005987

Pathways: Hormone Transport, Stem Cell Maintenance, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development