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UPP2 antibody (Uridine Phosphorylase 2) (AA 217-244)

Details for Product anti-UPP2 Antibody No. ABIN955473, Supplier: Log in to see
Antigen
  • uppl
  • zgc:55883
  • MGC89054
  • MGC140537
  • UDRPASE2
  • UP2
  • UPASE2
  • 1700124F02Rik
  • AI266885
Epitope
AA 217-244, C-Term
18
16
2
1
Reactivity
Human, Mouse (Murine)
21
5
Host
Rabbit
20
2
Clonality
Polyclonal
Conjugate
This UPP2 antibody is un-conjugated
2
2
2
2
2
2
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
21
15
14
2
Supplier
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Immunogen KLH conjugated synthetic peptide between 217-244 amino acids from the C-terminal region of human UPP2
Isotype Ig
Specificity This antibody detects Uridine phosphorylase 2 (UPP2) (C-term).
Cross-Reactivity (Details) Species reactivity (tested):Human, mouse
Purification Protein A column followed by peptide affinity purification
Background Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose-or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Shows substrate specificity and accept uridine, deoxyuridine, and thymidine as well as the two pyrimidine nucleoside analogs 5-fluorouridine and 5-fluoro-2(')-deoxyuridine as substrates.Synonyms: UPase 2, UrdPase 2
Gene ID 151531
NCBI Accession NP_001128570
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer.
Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-UPP2 antibody (Uridine Phosphorylase 2) (AA 217-244) (ABIN955473) UPP2 antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin e...
Western Blotting (WB) image for anti-UPP2 antibody (Uridine Phosphorylase 2) (AA 217-244) (ABIN955473) UPP2 Antibody (C-term) western blot analysis in mouse heart tissue lysates (35 µg/lan...
Background publications Maestrini, Pagnamenta, Lamb et al.: "High-density SNP association study and copy number variation analysis of the AUTS1 and AUTS5 loci implicate the IMMP2L-DOCK4 gene region in autism susceptibility." in: Molecular psychiatry, Vol. 15, Issue 9, pp. 954-68, 2010 (PubMed).

Lamesch, Li, Milstein et al.: "hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes." in: Genomics, Vol. 89, Issue 3, pp. 307-15, 2007 (PubMed).

Johansson: "Identification of a novel human uridine phosphorylase." in: Biochemical and biophysical research communications, Vol. 307, Issue 1, pp. 41-6, 2003 (PubMed).

Russell, Cao, Zhang et al.: "Uridine phosphorylase association with vimentin. Intracellular distribution and localization." in: The Journal of biological chemistry, Vol. 276, Issue 16, pp. 13302-7, 2001 (PubMed).