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Details for Product No. ABIN955473

Uridine Phosphorylase 2 (UPP2) (C-Term), (AA 217-244) antibody

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Antigen
Synonyms UP2, UPASE2, AI266885, UDRPASE2, 1700124F02Rik, uppl, zgc:55883, MGC89054, MGC140537
Epitope
»Alternatives C-Term, AA 217-244
Reactivity
»Alternatives Human, Mouse (Murine)
Host
»Alternatives Rabbit
Clonality Polyclonal
Application
»Alternatives ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
Pubmed 4 references available
Catalog no. ABIN955473
Quantity 0.4 mL
Price
346.50 $   Plus shipping costs $45.00
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Availability Will be delivered in 6 to 8 Business Days
Immunogen KLH conjugated synthetic peptide between 217-244 amino acids from the C-terminal region of human UPP2
Specificity This antibody detects Uridine phosphorylase 2 (UPP2) (C-term).
Purification Protein A column followed by peptide affinity purification
Background Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose-or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Shows substrate specificity and accept uridine, deoxyuridine, and thymidine as well as the two pyrimidine nucleoside analogs 5-fluorouridine and 5-fluoro-2(')-deoxyuridine as substrates.
Alternate names: UPase 2, UrdPase 2
Gene ID 151531
NCBI Accession NP_001128570
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09% (w/v) sodium azide
Preservative Sodium azide
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer.
Expiry Date 12 months
Background publications Russell, Cao, Zhang et al.: "Uridine phosphorylase association with vimentin. Intracellular distribution and localization." in: The Journal of biological chemistry, Vol. 276, Issue 16, pp. 13302-7, 2001 (PubMed).

Johansson: "Identification of a novel human uridine phosphorylase." in: Biochemical and biophysical research communications, Vol. 307, Issue 1, pp. 41-6, 2003 (PubMed).

Lamesch, Li, Milstein et al.: "hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes." in: Genomics, Vol. 89, Issue 3, pp. 307-15, 2007 (PubMed).

Maestrini, Pagnamenta, Lamb et al.: "High-density SNP association study and copy number variation analysis of the AUTS1 and AUTS5 loci implicate the IMMP2L-DOCK4 gene region in autism susceptibility." in: Molecular psychiatry, Vol. 15, Issue 9, pp. 954-68, 2010 (PubMed).

Alternatives for antigen "Uridine Phosphorylase 2 (UPP2)", type "Antibodies"
Hosts (5), (1)
Reactivities (5), (4)
Applications (6), (2), (1)
Epitopes (4), (2), (1)
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