Ectodysplasin A2 Receptor antibody
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- Target See all Ectodysplasin A2 Receptor (EDA2R) Antibodies
- Ectodysplasin A2 Receptor (EDA2R)
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Ectodysplasin A2 Receptor antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Brand
- IHC-plus™
- Specificity
- Detects human X-linked ectodermal dysplasia receptor (XEDAR), a 33kD type III transmembrane protein of the TNFR (tumor necrosis factor receptor) superfamily. XEDAR is a homologue of the ectodermal dysplasia receptor (EDAR), and binds to an isoform of ectodysplasin termed EDA-A2. Binding of ectodysplasin to XEDAR results in the induction of apoptosis, and is thought to be involved ectodermal organ development. New evidence suggests XEDAR may also be involved in skeletal muscle development. Two predominant isoforms of XEDAR exist, XEDAR-s and XEDAR-L, produced by alternative splicing.
- Purification
- Purified
- Immunogen
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Recombinant human XEDAR.
Type of Immunogen: Recombinant protein - Isotype
- IgG
- Top Product
- Discover our top product EDA2R Primary Antibody
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- Application Notes
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Approved: IHC, IHC-P (2.5 μg/mL), WB (0.5 - 2 μg/mL)
Usage: Western Blot: Detects a band of approximately 33kD in 293 cell lysates. - Comment
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Target Species of Antibody: Human
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- PBS, 0.02 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- avoid freeze thaw cycles.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Short term 4°C, long term aliquot and store at -20°C, avoid freeze-thaw cycles.
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- Target
- Ectodysplasin A2 Receptor (EDA2R)
- Alternative Name
- EDA2R / XEDAR (EDA2R Products)
- Synonyms
- EDA-A2R antibody, EDAA2R antibody, TNFRSF27 antibody, XEDAR antibody, 9430060M22Rik antibody, Xedar antibody, RGD1564025 antibody, ectodysplasin A2 receptor antibody, EDA2R antibody, Eda2r antibody
- Background
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Name/Gene ID: EDA2R
Synonyms: EDA2R, EDA-A2R, EDAA2R, Ectodysplasin A2 receptor, TNFRSF27, XEDAR, EDA-A2 receptor, EDAR2 - Gene ID
- 60401
- UniProt
- Q9HAV5
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