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Details for Product No. ABIN965754

Chromobox Homolog 1 (CBX1) antibody

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Antigen
Synonyms CBX, M31, MOD1, p25beta, HP1-BETA, HP1Hsbeta, HP1Hs-beta, Cbx, Cbx-rs2, E430007M08Rik, HP1B, Hp1beta, cbx1, wu:fe14b09, zgc:55739
Reactivity
»Alternatives Human, Monkey
Host
»Alternatives Mouse
Clonality (Clone) Monoclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), ELISA
Pubmed 3 references available
Catalog no. ABIN965754
Quantity 0.1 mL
Price
426.25 $   Plus shipping costs $45.00
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Availability Will be delivered in 5 to 7 Business Days
Immunogen Purified recombinant fragment of human CBX1 expressed in E. Coli.
Clone 5A3
Purification Ascitic fluid
Alternative Name CBX1
Background This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family . The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The protein may play an important role in the epigenetic control of chromatin structure and gene expression. Several related pseudogenes are located on chromosomes 1, 3, and X. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Gene ID 10951
Application Notes Western Bloting: 1/500 - 1/2000.
Immunofluorescence: 1/200 - 1/1000.
Flow cytometry: 1/200 - 1/400.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.
Restrictions For Research Use only
Preservative Sodium azide
Storage 4 °C
Product cited in: Hughes-Davies, Huntsman, Ruas et al.: "EMSY links the BRCA2 pathway to sporadic breast and ovarian cancer." in: Cell, Vol. 115, Issue 5, pp. 523-35, 2003 (PubMed).

Stelzl, Worm, Lalowski et al.: "A human protein-protein interaction network: a resource for annotating the proteome." in: Cell, Vol. 122, Issue 6, pp. 957-68, 2005 (PubMed).

Olsen, Blagoev, Gnad et al.: "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks." in: Cell, Vol. 127, Issue 3, pp. 635-48, 2006 (PubMed).

Alternatives for antigen "Chromobox Homolog 1 (CBX1)", type "Antibodies"
Hosts (27), (13), (12), (4)
Reactivities (51), (27), (22), (15), (14), (8), (6), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Applications (46), (23), (10), (9), (7), (6), (6), (4), (3), (2), (1), (1), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (6), (5), (2), (2), (2), (1), (1), (1), (1), (1)
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