MME antibody (Membrane Metallo-Endopeptidase)

Details for Product anti-MME Antibody No. ABIN965761, Supplier: Log in to see
Antigen
  • MME
  • NEP
  • CD10
  • CALLA
  • CAK
  • CD167
  • DDR
  • EDDR1
  • HGK2
  • MCK10
  • NTRK4
  • PTK3
  • PTK3A
  • RTK6
  • TRKE
  • AV378681
  • Mmel
  • 6030454K05Rik
  • C85356
  • SFE
  • Nep
  • membrane metallo-endopeptidase
  • discoidin domain receptor tyrosine kinase 1
  • matrix metallopeptidase 12
  • membrane metallo endopeptidase
  • MME
  • DDR1
  • Mmp12
  • Mme
Alternatives
anti-Human MME antibody for Complement Mediated Cell Depletion
Reactivity
Human
620
97
83
16
14
4
3
3
2
2
2
2
1
1
1
1
Host
Mouse
437
196
4
3
Clonality (Clone)
Monoclonal ()
Conjugate
This MME antibody is un-conjugated
61
48
43
23
11
10
10
10
9
8
6
6
6
6
6
5
5
5
5
3
3
3
3
3
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Acetone-fixed) (IHC (af)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Flow Cytometry (FACS)
313
305
212
178
130
83
83
49
49
21
13
10
5
4
3
2
2
2
1
1
1
1
1
Options
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Immunogen RAJI (Burkitt's lymphoma) cells.
Clone B396 (FR4D11)
Isotype IgG1
Specificity This antibody reacts with human common acute lymphoblastic leukemia antigen, a 100 kD glycoprotein.
Purification Purified.
Alternative Name CD10,CALLA (MME Antibody Abstract)
Gene ID 4311
Pathways RTK Signaling, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Smooth Muscle Cell Migration
Application Notes Immunofluorescence: 5-20 ug/mL.
Flow cytometry: 1-5 ug/10^6 cells.
Immunohistochemistry: 5-20 ug/mL on frozen sections using avidin-biotin system. This antibody was not quality controlled in flow cytometry.
Staining Procedure: This antibody can be used on acetone fixed frozen cryostat sections.
Comment

Recommended Positive Control: Tonsil, Lymph Node, and Small Intestine

Restrictions For Research Use only
Format Liquid
Concentration 0.4 mg/ml.
Buffer 50 mM Sodium Borate, 150 mM Sodium Chloride, 20% Glycerol, pH 8.0
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Background publications Lavabre-Bertrand, Janossy, Ivory, Peters, Secker-Walker, Porwit-MacDonald: "Leukemia-associated changes identified by quantitative flow cytometry: I. CD10 expression." in: Cytometry, Vol. 18, Issue 4, pp. 209-17, 1995 (PubMed).

Tran-Paterson, Boileau, Giguère, Letarte: "Comparative levels of CALLA/neutral endopeptidase on normal granulocytes, leukemic cells, and transfected COS-1 cells." in: Blood, Vol. 76, Issue 4, pp. 775-82, 1990 (PubMed).

LeBien, McCormack: "The common acute lymphoblastic leukemia antigen (CD10)--emancipation from a functional enigma." in: Blood, Vol. 73, Issue 3, pp. 625-35, 1989 (PubMed).

Brown, Capellaro, Greaves: "Leukemia-associated antigens in man." in: Journal of the National Cancer Institute, Vol. 55, Issue 6, pp. 1281-9, 1976 (PubMed).

Product cited in: Mizoguchi: "[Diagnosis and therapy of megakaryoblastic leukemia]." in: Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, Vol. 82, Issue 7, pp. 1053-7, 1993 (PubMed).

Pezzutto, Dörken, Rabinovitch, Ledbetter, Moldenhauer, Clark: "CD19 monoclonal antibody HD37 inhibits anti-immunoglobulin-induced B cell activation and proliferation." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 138, Issue 9, pp. 2793-9, 1987 (PubMed).