Membrane Metallo-Endopeptidase (MME) antibody

Details for Product No. ABIN965761
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Antigen
Synonyms MME, NEP, CD10, CALLA, CAK, CD167, DDR, EDDR1, HGK2, MCK10, NTRK4, PTK3, PTK3A, RTK6, TRKE, AV378681, Mmel, 6030454K05Rik, C85356, SFE, Nep
Reactivity
Human
(484), (46), (44), (1)
Host
Mouse
(335), (164), (2)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(50), (48), (41), (24), (6), (5), (4), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Application
Immunohistochemistry (Frozen Sections) (IHC (fro)), Flow Cytometry (FACS), Immunohistochemistry (Acetone-fixed) (IHC (af))
(255), (203), (111), (94), (90), (63), (51), (27), (16), (10), (7), (6), (4), (4), (4), (3), (3), (2), (2), (1), (1)
Pubmed 6 references available
Quantity 0.2 mg
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Immunogen RAJI (Burkitt's lymphoma) cells.
Clone B396 (FR4D11)
Isotype IgG1
Specificity This antibody reacts with human common acute lymphoblastic leukemia antigen, a 100 kD glycoprotein.
Purification Purified.
Alternative Name CD10,CALLA (MME Antibody Abstract)
Gene ID 4311
Application Notes Immunofluorescence: 5-20 ug/mL.
Flow cytometry: 1-5 ug/10^6 cells.
Immunohistochemistry: 5-20 ug/mL on frozen sections using avidin-biotin system. This antibody was not quality controlled in flow cytometry.
Staining Procedure: This antibody can be used on acetone fixed frozen cryostat sections.
Comment

Recommended Positive Control: Tonsil, Lymph Node, and Small Intestine

Restrictions For Research Use only
Format Liquid
Concentration 0.4 mg/ml.
Buffer 50 mM Sodium Borate, 150 mM Sodium Chloride, 20% Glycerol, pH 8.0
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Product cited in: Mizoguchi: "[Diagnosis and therapy of megakaryoblastic leukemia]." in: Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, Vol. 82, Issue 7, pp. 1053-7, 1993 (PubMed).

Pezzutto, Dörken, Rabinovitch et al.: "CD19 monoclonal antibody HD37 inhibits anti-immunoglobulin-induced B cell activation and proliferation." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 138, Issue 9, pp. 2793-9, 1987 (PubMed).

Background publications Lavabre-Bertrand, Janossy, Ivory et al.: "Leukemia-associated changes identified by quantitative flow cytometry: I. CD10 expression." in: Cytometry, Vol. 18, Issue 4, pp. 209-17, 1995 (PubMed).

LeBien, McCormack: "The common acute lymphoblastic leukemia antigen (CD10)--emancipation from a functional enigma." in: Blood, Vol. 73, Issue 3, pp. 625-35, 1989 (PubMed).

Tran-Paterson, Boileau, Giguère et al.: "Comparative levels of CALLA/neutral endopeptidase on normal granulocytes, leukemic cells, and transfected COS-1 cells." in: Blood, Vol. 76, Issue 4, pp. 775-82, 1990 (PubMed).

Brown, Capellaro, Greaves: "Leukemia-associated antigens in man." in: Journal of the National Cancer Institute, Vol. 55, Issue 6, pp. 1281-9, 1976 (PubMed).

Validation Images
Catalog No. ABIN965761
295.63 $
Plus shipping costs $45.00
Quantity
Price
0.2 mg
295.63 $

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