Lysine (K)-Specific Demethylase 1A (KDM1A) antibody

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Antigen
  • KDM1
  • AOF2
  • KDM1A
  • DKFZp459N2450
  • aof2
  • kdm1
  • lsd1
  • xLSD1
  • BHC110
  • LSD1
  • 1810043O07Rik
  • AA408884
  • Aof2
  • D4Ertd478e
  • Kdm1
  • Lsd1
  • mKIAA0601
  • RGD1562975
  • wu:fb82e06
  • wu:fc51a02
  • wu:fj36a05
  • wu:fj66b06
  • ARABIDOPSIS LYSINE-SPECIFIC HISTONE DEMETHYLASE
  • ATLSD1
  • ATSWP1
  • F23N19.21
  • F23N19_21
  • LSD1-like 1
  • LYSINE-SPECIFIC HISTONE DEMETHYLASE
  • SWP1
  • amine oxidase (flavin containing) domain 2
  • lysine (K)-specific demethylase 1
  • lysine (K)-specific demethylase 1A
  • lysine (K)-specific demethylase 1a
  • Lysine-specific histone demethylase 1-1
  • AOF2
  • KDM1
  • KDM1A
  • kdm1a
  • Kdm1a
  • LDL1
Alternatives
anti-Human Lysine (K)-Specific Demethylase 1A antibody for ChIP DNA-Sequencing
Reactivity
Human
210
123
96
24
24
11
10
7
5
4
3
3
2
2
1
1
1
1
1
Host
162
50
3
Clonality
Monoclonal
Conjugate
Un-conjugated
2
2
2
2
2
2
2
2
2
2
2
2
2
2
Application
Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
177
61
60
48
31
26
16
14
10
8
6
6
3
3
1
1
1
1
Options
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Isotype IgG1
Specificity Ni-NTA purified truncated recombinant human LSD1 expressed in E. Coli strain BL21 (DE3)
Purification Crude Asites are purified by protein A affinity chromatography.
Alternative Name LSD1/AOF2 (KDM1A Antibody Abstract)
Background The amine oxidase domain 2(AOF2)gene encodes a nuclear protein(LSD1,~95kDa) containing a Swirm domain, a FAD-binding motif, and an amine oxidase domain. This protein is a component of several histone deacetylase complexes, though it silences genes by functioning as a histone demethylase. LSD1 is a chromatin-modifying enzyme, which serve as a docking module for the stabilization of the associated corepressor complex(es) on chromatin.
Gene ID 23028
Pathways Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Negative Regulation of intrinsic apoptotic Signaling
Application Notes Western Blot: 1: 500- 1: 2,000
IHC(P): 1: 500- 1: 2,000
IHC(F): 1: 500- 1: 2,000
ELISA: Propose dilution 1: 10,000.
Determining optimal working dilutions by titration test.
Restrictions For Research Use only
Storage -20 °C
Product cited in: Metzger, Wissmann, Yin, Müller, Schneider, Peters, Günther, Buettner, Schüle: "LSD1 demethylates repressive histone marks to promote androgen-receptor-dependent transcription." in: Nature, Vol. 437, Issue 7057, pp. 436-9, 2005 (PubMed).