MAP4K4 antibody (AA 400-500)
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- Target See all MAP4K4 Antibodies
- MAP4K4 (Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4))
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Binding Specificity
- AA 400-500
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This MAP4K4 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA
- Purification
- Ascitic fluid
- Immunogen
- Purified recombinant fragment of MAP4K4 (aa400-500) expressed in E. Coli.
- Clone
- 3C7B5
- Isotype
- IgG1
- Top Product
- Discover our top product MAP4K4 Primary Antibody
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- Application Notes
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Western Bloting: 1/500 - 1/2000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test. - Restrictions
- For Research Use only
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- Format
- Liquid
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C
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A conserved interaction between beta1 integrin/PAT-3 and Nck-interacting kinase/MIG-15 that mediates commissural axon navigation in C. elegans." in: Current biology : CB, Vol. 12, Issue 8, pp. 622-31, (2002) (PubMed).
: "Nck-interacting Ste20 kinase couples Eph receptors to c-Jun N-terminal kinase and integrin activation." in: Molecular and cellular biology, Vol. 20, Issue 5, pp. 1537-45, (2000) (PubMed).
: "Growth hormone gene expression in normal lymph nodes and lymphomas of the dog." in: Anticancer research, Vol. 20, Issue 4, pp. 2371-6, (2000) (PubMed).
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A conserved interaction between beta1 integrin/PAT-3 and Nck-interacting kinase/MIG-15 that mediates commissural axon navigation in C. elegans." in: Current biology : CB, Vol. 12, Issue 8, pp. 622-31, (2002) (PubMed).
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- Target
- MAP4K4 (Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4))
- Alternative Name
- MAP4K4 (MAP4K4 Products)
- Synonyms
- FLH21957 antibody, HGK antibody, MEKKK4 antibody, NIK antibody, 9430080K19Rik antibody, AU043147 antibody, AU045934 antibody, AW046177 antibody, Nik antibody, mitogen-activated protein kinase kinase kinase kinase 4 antibody, MAP4K4 antibody, Map4k4 antibody
- Background
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MAP4K4: mitogen-activated protein kinase kinase kinase kinase 4. The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase has been shown to specifically activate MAPK8/JNK. The activation of MAPK8 by this kinase is found to be inhibited by the dominant-negative mutants of MAP3K7/TAK1, MAP2K4/MKK4, and MAP2K7/MKK7, which suggests that this kinase may function through the MAP3K7-MAP2K4-MAP2K7 kinase cascade, and mediate the TNF-alpha signaling pathway. Alternatively spliced transcript variants encoding different isoforms have been identified.
Synonyms: HGK, NIK - Gene ID
- 9448
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