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Cyclin-Dependent Kinase Inhibitor 1B (p27, Kip1) (CDKN1B) antibody

Details for Product No. ABIN966734
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Antigen
Synonyms
P27, ISG12, FAM14D, ISG12A, KIP1, MEN4, CDKN4, MEN1B, P27KIP1, AA408329, AI843786, Kip1, p27, p27Kip1, 1500011J20Rik, 2610202L11Rik, Bridge-1, Cdki1b, cdkn1b, sb:cb611, wu:fb63g10, wu:fb64g10, wu:fe18 ... show more
P27, ISG12, FAM14D, ISG12A, KIP1, MEN4, CDKN4, MEN1B, P27KIP1, AA408329, AI843786, Kip1, p27, p27Kip1, 1500011J20Rik, 2610202L11Rik, Bridge-1, Cdki1b, cdkn1b, sb:cb611, wu:fb63g10, wu:fb64g10, wu:fe18e03, CDKN1B show less
Reactivity
Human, Mouse (Murine), Rat (Rattus)
(408), (178), (146), (81), (61), (54), (36), (13), (8), (3), (3), (1), (1), (1), (1)
Host
Rabbit
(379), (65), (14), (1), (1)
Clonality
Polyclonal
Conjugate
Un-conjugated
(21), (19), (17), (11), (11), (11), (6), (6), (6), (6), (6), (6), (6), (6), (2), (2)
Application
Immunohistochemistry (IHC)
(300), (197), (92), (84), (61), (60), (51), (29), (12), (10), (6), (5), (1)
Pubmed 5 references available
Quantity 100 µg
Options
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Availability Will be delivered in 5 to 7 Business Days
Catalog No. ABIN966734
385.00 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen The antiserum was produced against synthesized non-phosphopeptide derived from human p27Kip1 around the phosphorylation site of serine 10 (N-G-SP-P-S).
Specificity P27Kip1 (Ab-10) antibody detects endogenous levels of total p27Kip1 protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Alternative Name p27Kip1
Application Notes WB: 1:500~1:1000
IHC: 1:50~1:100.
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Product cited in: Boehm, Yoshimoto, Crook et al.: "A growth factor-dependent nuclear kinase phosphorylates p27(Kip1) and regulates cell cycle progression." in: The EMBO journal, Vol. 21, Issue 13, pp. 3390-401, 2002 (PubMed).

Chopra, Fernandez De Mattos, Lam et al.: "Jab1 co-activation of c-Jun is abrogated by the serine 10-phosphorylated form of p27Kip1." in: The Journal of biological chemistry, Vol. 277, Issue 36, pp. 32413-6, 2002 (PubMed).

McAllister, Becker-Hapak, Pintucci et al.: "Novel p27(kip1) C-terminal scatter domain mediates Rac-dependent cell migration independent of cell cycle arrest functions." in: Molecular and cellular biology, Vol. 23, Issue 1, pp. 216-28, 2002 (PubMed).

Connor, Kotchetkov, Cariou et al.: "CRM1/Ran-mediated nuclear export of p27(Kip1) involves a nuclear export signal and links p27 export and proteolysis." in: Molecular biology of the cell, Vol. 14, Issue 1, pp. 201-13, 2003 (PubMed).

Le, Claret, Lammayot et al.: "The role of cyclin-dependent kinase inhibitor p27Kip1 in anti-HER2 antibody-induced G1 cell cycle arrest and tumor growth inhibition." in: The Journal of biological chemistry, Vol. 278, Issue 26, pp. 23441-50, 2003 (PubMed).

Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN966734
385.00 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
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