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CDKN1B antibody (Cyclin-Dependent Kinase Inhibitor 1B (p27, Kip1))

Details for Product anti-CDKN1B Antibody No. ABIN966734, Supplier: Login to see New
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Antigen
Synonyms
CDKN1B, CIB, CIBP, KIP1, PRKDCIP, SIP2-28, p27Kip1, AA408329, AI843786, Kip1, p27, CDKN4, Cdki1b, P27KIP1, MEN1B, MEN4, cdkn1bl, cdkn1b, sb:cb611, wu:fb63g10, wu:fb64g10, wu:fe18e03, FAM14D, ISG12, IS ... show more
CDKN1B, CIB, CIBP, KIP1, PRKDCIP, SIP2-28, p27Kip1, AA408329, AI843786, Kip1, p27, CDKN4, Cdki1b, P27KIP1, MEN1B, MEN4, cdkn1bl, cdkn1b, sb:cb611, wu:fb63g10, wu:fb64g10, wu:fe18e03, FAM14D, ISG12, ISG12A, P27, 1500011J20Rik, 2610202L11Rik, Bridge-1 show less
Alternatives
Reactivity
Human, Mouse (Murine), Rat (Rattus)
(601), (211), (149), (21), (21), (16), (10), (7), (6), (5), (3), (2), (2), (2), (2), (1), (1)
Host
Rabbit
(513), (105), (37), (4), (2), (1)
Clonality
Polyclonal
Conjugate
This CDKN1B antibody is un-conjugated
(31), (31), (27), (25), (25), (25), (6), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Application
Immunohistochemistry (IHC)
(451), (305), (184), (103), (102), (87), (52), (30), (30), (16), (15), (9), (3), (1), (1), (1)
Pubmed 5 references available
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Quantity 100 μg
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Immunogen The antiserum was produced against synthesized non-phosphopeptide derived from human p27Kip1 around the phosphorylation site of serine 10 (N-G-SP-P-S).
Specificity P27Kip1 (Ab-10) antibody detects endogenous levels of total p27Kip1 protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Alternative Name p27Kip1 (CDKN1B Antibody Abstract)
Pathways Cell Division Cycle, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
Application Notes WB: 1:500~1:1000
IHC: 1:50~1:100.
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Product cited in: Le, Claret, Lammayot et al.: "The role of cyclin-dependent kinase inhibitor p27Kip1 in anti-HER2 antibody-induced G1 cell cycle arrest and tumor growth inhibition." in: The Journal of biological chemistry, Vol. 278, Issue 26, pp. 23441-50, 2003 (PubMed).

Connor, Kotchetkov, Cariou et al.: "CRM1/Ran-mediated nuclear export of p27(Kip1) involves a nuclear export signal and links p27 export and proteolysis." in: Molecular biology of the cell, Vol. 14, Issue 1, pp. 201-13, 2003 (PubMed).

Chopra, Fernandez De Mattos, Lam et al.: "Jab1 co-activation of c-Jun is abrogated by the serine 10-phosphorylated form of p27Kip1." in: The Journal of biological chemistry, Vol. 277, Issue 36, pp. 32413-6, 2002 (PubMed).

Boehm, Yoshimoto, Crook et al.: "A growth factor-dependent nuclear kinase phosphorylates p27(Kip1) and regulates cell cycle progression." in: The EMBO journal, Vol. 21, Issue 13, pp. 3390-401, 2002 (PubMed).

Background publications McAllister, Becker-Hapak, Pintucci et al.: "Novel p27(kip1) C-terminal scatter domain mediates Rac-dependent cell migration independent of cell cycle arrest functions." in: Molecular and cellular biology, Vol. 23, Issue 1, pp. 216-28, 2002 (PubMed).

Catalog No. ABIN966734
$398.75
Plus shipping costs $45.00

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