Tumor Protein P53 (TP53) antibody

Details for Product No. ABIN966758
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Antigen
Synonyms tp53, p53, TP53, Tp53, bbl, bfy, bhy, p44, TpMs, BCC7, LFS1, P53, TRP53, Trp53, Xp53, brp53, drp53, etID22686.5, fb40d06, wu:fb40d06, zgc:111919
Reactivity
Human
(1340), (311), (266), (78), (76), (66), (48), (24), (15), (12), (8), (6), (5), (5), (4), (3), (3), (2), (2), (2), (1)
Host
Rabbit
(990), (426), (7), (5), (3), (2), (1)
Clonality
Polyclonal
Conjugate
Un-conjugated
(36), (31), (22), (16), (16), (16), (16), (16), (16), (16), (16), (11), (11), (11), (5), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Immunohistochemistry (IHC)
(1064), (487), (354), (332), (264), (215), (160), (150), (111), (85), (22), (22), (14), (7), (5), (4), (3), (3), (2), (2), (2), (1), (1), (1)
Pubmed 4 references available
Quantity 100 µg
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Catalog No. ABIN966758
385.00 $
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Immunogen The antiserum was produced against synthesized non-phosphopeptide derived from human p53 around the phosphorylation site of serine15 (P-L-SP-Q-E).
Specificity P53 (Ab-15) antibody detects endogenous levels of total p53 protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Alternative Name P53
Application Notes WB: 1:500~1:1000
IHC: 1:50~1:100.
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Product cited in: Wang, Wiltshire, Wang et al.: "ATM-dependent CHK2 activation induced by anticancer agent, irofulven." in: The Journal of biological chemistry, Vol. 279, Issue 38, pp. 39584-92, 2004 (PubMed).

Li, Zhang, Sejas et al.: "Hypoxia-induced nucleophosmin protects cell death through inhibition of p53." in: The Journal of biological chemistry, Vol. 279, Issue 40, pp. 41275-9, 2004 (PubMed).

Vega, Sevilla, Lazo: "p53 Stabilization and accumulation induced by human vaccinia-related kinase 1." in: Molecular and cellular biology, Vol. 24, Issue 23, pp. 10366-80, 2004 (PubMed).

Lin, Chao, Saito et al.: "p53 induces differentiation of mouse embryonic stem cells by suppressing Nanog expression." in: Nature cell biology, Vol. 7, Issue 2, pp. 165-71, 2005 (PubMed).

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