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p53 antibody (Tumor Protein P53)

Details for Product anti-TP53 Antibody No. ABIN966758, Supplier: Login to see
Antigen
  • tp53
  • p53
  • TP53
  • Tp53
  • bbl
  • bfy
  • bhy
  • p44
  • TpMs
  • BCC7
  • LFS1
  • P53
  • TRP53
  • Trp53
  • Xp53
  • brp53
  • drp53
  • etID22686.5
  • fb40d06
  • wu:fb40d06
  • zgc:111919
Alternatives
anti-Human p53 antibody for Immunohistochemistry (Paraffin-embedded Sections)
Reactivity
Human
1740
312
256
71
30
11
11
10
10
10
9
7
5
4
4
4
4
3
3
2
2
2
1
Host
Rabbit
1223
606
8
4
3
1
1
Clonality
Polyclonal
Conjugate
This p53 antibody is un-conjugated
58
49
32
31
21
21
17
15
15
14
14
14
14
14
14
3
3
3
3
3
3
3
3
3
3
2
1
1
Application
Immunohistochemistry (IHC)
1358
565
511
333
330
303
225
160
106
94
54
35
33
18
16
13
11
11
11
9
4
3
3
3
2
2
2
2
1
1
1
1
Supplier
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Immunogen The antiserum was produced against synthesized non-phosphopeptide derived from human p53 around the phosphorylation site of serine15 (P-L-SP-Q-E).
Specificity P53 (Ab-15) antibody detects endogenous levels of total p53 protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Alternative Name P53 (TP53 Antibody Abstract)
Pathways p53 Signaling, MAPK Signaling, PI3K-Akt Signaling, Apoptosis, AMPK Signaling
Application Notes WB: 1:500~1:1000
IHC: 1:50~1:100.
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Product cited in: Lin, Chao, Saito et al.: "p53 induces differentiation of mouse embryonic stem cells by suppressing Nanog expression." in: Nature cell biology, Vol. 7, Issue 2, pp. 165-71, 2005 (PubMed).

Vega, Sevilla, Lazo: "p53 Stabilization and accumulation induced by human vaccinia-related kinase 1." in: Molecular and cellular biology, Vol. 24, Issue 23, pp. 10366-80, 2004 (PubMed).

Li, Zhang, Sejas et al.: "Hypoxia-induced nucleophosmin protects cell death through inhibition of p53." in: The Journal of biological chemistry, Vol. 279, Issue 40, pp. 41275-9, 2004 (PubMed).

Background publications Wang, Wiltshire, Wang et al.: "ATM-dependent CHK2 activation induced by anticancer agent, irofulven." in: The Journal of biological chemistry, Vol. 279, Issue 38, pp. 39584-92, 2004 (PubMed).