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Retinoblastoma 1 antibody (RB1)

Details for Product anti-RB1 Antibody No. ABIN966953, Supplier: Login to see New
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Antigen
Synonyms RB1, OSRC, RB, p105-Rb, pRb, pp110, Rb, Rb-1, zgc:154147, P105-RB, PP110, RB11
Alternatives
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Reactivity
Human, Mouse (Murine), Rat (Rattus)
(526), (253), (229), (11), (8), (7), (5), (5), (4), (4), (3), (3), (2), (2)
Host
Rabbit
(467), (68), (3)
Clonality
Polyclonal
Conjugate
This Retinoblastoma 1 antibody is un-conjugated
(22), (20), (20), (15), (13), (13), (10), (9), (9), (7), (7), (7), (7), (7), (7)
Application
Immunohistochemistry (IHC)
(323), (215), (184), (83), (74), (73), (45), (35), (15), (13), (10), (8), (6), (5), (2), (2), (2), (1), (1)
Pubmed 2 references available
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Quantity 100 μg
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Availability Will be delivered in 5 to 7 Business Days
Immunogen The antiserum was produced against synthesized non-phosphopeptide derived from human Rb around the phosphorylation site of serine 780 (T-L-SP-P-I).
Specificity Rb (Ab-780) antibody detects endogenous levels of taotal Rb protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Alternative Name Rb (RB1 Antibody Abstract)
Pathways Cell Division Cycle
Application Notes WB: 1:500~1:1000
IHC: 1:50~1:100.
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Product cited in: Roesch, Becker, Meyer et al.: "Overexpression and hyperphosphorylation of retinoblastoma protein in the progression of malignant melanoma." in: Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, Vol. 18, Issue 4, pp. 565-72, 2005 (PubMed).

Background publications Kitagawa, Higashi, Jung et al.: "The consensus motif for phosphorylation by cyclin D1-Cdk4 is different from that for phosphorylation by cyclin A/E-Cdk2." in: The EMBO journal, Vol. 15, Issue 24, pp. 7060-9, 1997 (PubMed).

Catalog No. ABIN966953
$398.75
Plus shipping costs $45.00

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