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Details for Product No. ABIN966954

Retinoblastoma 1 (RB1) antibody

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Antigen
Synonyms RB, pRb, OSRC, pp110, p105-Rb, Rb, Rb-1, P105-RB, PP110, RB11, zgc:154147, RB1
Reactivity
»Alternatives Human, Mouse (Murine), Rat (Rattus)
Host
»Alternatives Rabbit
Clonality Polyclonal
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Immunohistochemistry (IHC)
Pubmed 3 references available
Catalog no. ABIN966954
Quantity 100 µg
Price
385.00 $   Plus shipping costs $45.00
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Availability Will be delivered in 5 to 7 Business Days
Immunogen The antiserum was produced against synthesized non-phosphopeptide derived from human Rb around the phosphorylation site of serine 795 (P-S-SP-P-L).
Specificity Rb (Ab-795) antibody detects endogenous levels of total Rb protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Alternative Name Rb
Application Notes WB: 1:500~1:1000.
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative Sodium azide
Storage -20 °C
Product cited in: Knudsen, Wang: "Differential regulation of retinoblastoma protein function by specific Cdk phosphorylation sites." in: The Journal of biological chemistry, Vol. 271, Issue 14, pp. 8313-20, 1996 (PubMed).

Knudsen, Wang: "Dual mechanisms for the inhibition of E2F binding to RB by cyclin-dependent kinase-mediated RB phosphorylation." in: Molecular and cellular biology, Vol. 17, Issue 10, pp. 5771-83, 1997 (PubMed).

Roesch, Becker, Meyer et al.: "Overexpression and hyperphosphorylation of retinoblastoma protein in the progression of malignant melanoma." in: Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, Vol. 18, Issue 4, pp. 565-72, 2005 (PubMed).

Alternatives for antigen "Retinoblastoma 1 (RB1)", type "Antibodies"
Hosts (356), (106), (2)
Reactivities (446), (238), (222), (109), (87), (76), (48), (3), (2), (1), (1), (1), (1)
Applications (302), (134), (132), (100), (100), (74), (45), (20), (19), (16), (13), (2), (1)
Conjugates (13), (10), (10), (10), (10), (10), (10), (10), (10), (10), (10)
Epitopes (41), (36), (33), (24), (23), (21), (20), (20), (18), (18), (17), (7), (7), (6), (5), (4), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
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