SRY (Sex Determining Region Y)-Box 2 (SOX2) antibody

Details for Product No. ABIN967072
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Antigen
Synonyms Qscn6, Qsox, Sox-2, rSOx, ANOP3, MCOPS3, RGD1565646, SRY-box2, Xsox-2, anop3, mcops3, sox-2, lcc, ysb, cb236, wu:fb83g04, wu:fc14d07, zgc:65860, zgc:77389
Reactivity
Human
(196), (66), (45), (21), (20), (20), (16), (12), (5), (4), (4), (3), (2), (2), (1), (1), (1)
Host
Mouse
(160), (42), (5)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(11), (6), (6), (6), (5), (5), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA
(144), (73), (39), (33), (31), (28), (26), (24), (10), (10), (8), (3), (1)
Pubmed 3 references available
Quantity 0.1 mL
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Catalog No. ABIN967072
426.25 $
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Immunogen Purified recombinant fragment of human SOX2 expressed in E. Coli.
Clone 10F10
Isotype IgG1
Purification Ascitic fluid
Alternative Name SOX2
Background Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency.
Synonyms: lcc, ysb, Sox-2, Sox2
Molecular Weight 34kDa
Gene ID 20674
Research Area Embryogenesis, Embryonic stem cells, Reproduction, Transcription Factors, Neural Stem Cell marker
Application Notes Western Bloting: 1/500 - 1/2000.
Immunohistochemistry: 1/200 - 1/1000.
Immunofluorescence: 1/200 - 1/1000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.
Restrictions For Research Use only
Format Liquid
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Product cited in: Tay, Zhang, Thomson et al.: "MicroRNAs to Nanog, Oct4 and Sox2 coding regions modulate embryonic stem cell differentiation." in: Nature, Vol. 455, Issue 7216, pp. 1124-8, 2008 (PubMed).

Qin, Gan, Shao et al.: "Mouse meningiocytes express Sox2 and yield high efficiency of chimeras after nuclear reprogramming with exogenous factors." in: The Journal of biological chemistry, Vol. 283, Issue 48, pp. 33730-5, 2008 (PubMed).

Dabdoub, Puligilla, Jones et al.: "Sox2 signaling in prosensory domain specification and subsequent hair cell differentiation in the developing cochlea." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 47, pp. 18396-401, 2008 (PubMed).

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