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TAF2 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 150kDa (TAF2) (C-Term) antibody
Yeast (Saccharomyces cerevisiae)
Alternatives Immunohistochemistry (IHC)
|10 references available|
|Price||452.38 $ Plus shipping costs $45.00|
|Availability||Will be delivered in 5 to 7 Business Days|
|Immunogen||Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to C-terminal residues of Baker's yeast (Saccharomyces cerevisiae) TAF2(TBP-associated factor 2, Transcription initiation factor TFIID subunit 2)|
TAF2(TBP-associated factor 2, Transcription initiation factor TFIID subunit 2) functions as a component of the DNA-binding general transcription factor complex TFIID. Binding of TFIID to a promoter (with or without TATA element) is the initial step in pre-initiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modification (histone acetylation by TAF1), facilitation of DNA opening and initiation of transcription. The 1.2 MDa TFIID complex is composed of TATA binding protein (TBP) and the 14 TBP-associated factors. One copy of each TAF1, TAF2, TAF3, TAF7, TAF8, TAF11, TAF13, two copies of each TAF4, TAF5, TAF6, TAF9, TAF10, TAF12, and three copies of TAF14.
Synonyms: TAF150(TBP-associated factor 150), TAFII-150, TSM1, YCR42C, YCR724
|Research Area||Chromatin and Nuclear Signaling, Transcription Factors|
|Restrictions||For Research Use only|
Jacquet, Buhler, Iborra et al.: "The MAT locus revisited within a 9.8 kb fragment of chromosome III containing BUD5 and two new open reading frames." in: Yeast (Chichester, England), Vol. 7, Issue 8, pp. 881-8, 1992 (PubMed).
Ray, White, Haber: "The TSM1 gene of Saccharomyces cerevisiae overlaps the MAT locus." in: Current genetics, Vol. 20, Issue 1-2, pp. 25-31, 1991 (PubMed).
Poon, Bai, Campbell et al.: "Identification and characterization of a TFIID-like multiprotein complex from Saccharomyces cerevisiae." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 92, Issue 18, pp. 8224-8, 1995 (PubMed).
Sanders, Weil: "Identification of two novel TAF subunits of the yeast Saccharomyces cerevisiae TFIID complex." in: The Journal of biological chemistry, Vol. 275, Issue 18, pp. 13895-900, 2000 (PubMed).
Leurent, Sanders, Ruhlmann et al.: "Mapping histone fold TAFs within yeast TFIID." in: The EMBO journal, Vol. 21, Issue 13, pp. 3424-33, 2002 (PubMed).
Sanders, Garbett, Weil: "Molecular characterization of Saccharomyces cerevisiae TFIID." in: Molecular and cellular biology, Vol. 22, Issue 16, pp. 6000-13, 2002 (PubMed).
Martinez: "Multi-protein complexes in eukaryotic gene transcription." in: Plant molecular biology, Vol. 50, Issue 6, pp. 925-47, 2003 (PubMed).
Ghaemmaghami, Huh, Bower et al.: "Global analysis of protein expression in yeast." in: Nature, Vol. 425, Issue 6959, pp. 737-41, 2003 (PubMed).
Chi, Huttenhower, Geer et al.: "Analysis of phosphorylation sites on proteins from Saccharomyces cerevisiae by electron transfer dissociation (ETD) mass spectrometry." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Issue 7, pp. 2193-8, 2007 (PubMed).
Li, Gerber, Rudner et al.: "Large-scale phosphorylation analysis of alpha-factor-arrested Saccharomyces cerevisiae." in: Journal of proteome research, Vol. 6, Issue 3, pp. 1190-7, 2007 (PubMed).
|Hosts||Rabbit (10), Mouse (2)|
|Reactivities||Human (7), Yeast (Saccharomyces cerevisiae) (5), Mouse (Murine) (2), Chicken (1), Dog (Canine) (1), Rat (Rattus) (1), Xenopus laevis (1), Zebrafish (1)|
|Applications||Immunohistochemistry (IHC) (7), Western Blotting (WB) (7), ELISA (4), Flow Cytometry (FACS) (2), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (1)|
|Epitopes||C-Term (4), AA 782-1121 (1), C-Term,AA 1159-1188 (1), Internal Region (1), N-Term (1), N-Term,Middle Region (1)|