Toll-Like Receptor 9 (TLR9) (N-Term) antibody

Details for Product No. ABIN967190
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Antigen
Synonyms CD289
Epitope
N-Term
(47), (29), (19), (14), (11), (9), (7), (6), (6), (6), (5), (4), (4), (4), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Mouse (Murine)
(211), (104), (38), (5), (4), (2), (1), (1), (1), (1), (1), (1)
Host
Rabbit
(134), (80), (22), (15), (4), (2)
Clonality
Polyclonal
Conjugate
Un-conjugated
(27), (22), (14), (6), (6), (5), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Immunohistochemistry (IHC)
(198), (108), (75), (66), (56), (39), (17), (13), (10), (10), (7), (6), (4), (4), (3), (3), (2), (2), (1), (1)
Pubmed 5 references available
Quantity 0.1 mg
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Immunogen Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to N-terminal residues of mouse Tlr9 (Toll-like receptor 9)
Alternative Name Tlr9 (TLR9 Antibody Abstract)
Background Tlr9 (Toll-like receptor 9) participates in the innate immune response to microbial agents. Tlr9 (Toll-like receptor 9) detects the unmethylated cytidine-phosphate-guanosine (CpG) motifs present in bacterial DNA. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Tlr9 (Toll-like receptor 9) plays a role in defense against sytemic mouse cytomegalovirus infection. Tlr9 (Toll-like receptor 9) binds MYD88 via their respective TIR domains and interacts with CNPY3. Tlr9 (Toll-like receptor 9) belongs to the Toll-like receptor family and contains 26 LRR (leucine-rich) repeats and 1 TIR domain.
Restrictions For Research Use only
Product cited in: Kiyokawa, Akashi-Takamura, Shibata et al.: "A single base mutation in the PRAT4A gene reveals differential interaction of PRAT4A with Toll-like receptors." in: International immunology, Vol. 20, Issue 11, pp. 1407-15, 2008 (PubMed).

Tabeta, Georgel, Janssen et al.: "Toll-like receptors 9 and 3 as essential components of innate immune defense against mouse cytomegalovirus infection." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 10, pp. 3516-21, 2004 (PubMed).

Chuang, Lee, Kline et al.: "Toll-like receptor 9 mediates CpG-DNA signaling." in: Journal of leukocyte biology, Vol. 71, Issue 3, pp. 538-44, 2002 (PubMed).

Bauer, Kirschning, Häcker et al.: "Human TLR9 confers responsiveness to bacterial DNA via species-specific CpG motif recognition." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 98, Issue 16, pp. 9237-42, 2001 (PubMed).

Hemmi, Takeuchi, Kawai et al.: "A Toll-like receptor recognizes bacterial DNA." in: Nature, Vol. 408, Issue 6813, pp. 740-5, 2000 (PubMed).

Validation Images
Catalog No. ABIN967190
466.13 $
Plus shipping costs $45.00
Quantity
Price
0.1 mg
466.13 $

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