TLR9 antibody (AA 268-300)

Catalog No. ABIN531988

Product Details anti-TLR9 Antibody

Target: TLR9 (Toll-Like Receptor 9 (TLR9))

Binding Specificity: AA 268-300

Reactivity: Human, Mouse, Rat, Monkey

Host: Mouse

Clonality: Monoclonal

Conjugate: This TLR9 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunoprecipitation (IP), Immunofluorescence (IF)

Purpose: Mouse monoclonal antibody raised against synthetic peptide of TLR9.

Cross-Reactivity: Human, Monkey, Mouse, Rat

Immunogen: A synthetic peptide (conjugated with KLH) corresponding to amino acids 268-300 of human TLR9 isoform A.

Clone: 26C593-2

Isotype: IgG1

Application Details

Application Notes: ELISA (1:100-1:2000)
Flow Cytometry
Immunocytochemistry (1:10-1:500)
Immunofluorescence (1:10-1:500)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (5 μg/mL)
Immunoprecipitation (1:10-1:500)
Western Blot (2-5 μg/mL)

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In PBS (0.05 % sodium azide).

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for short term. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.

References for anti-TLR9 antibody (ABIN531988)

Shi, Yu, Xie, Wang, Zhang, Zheng: "Activation of TLR9-dependent p38MAPK pathway in the pathogenesis of primary Sjögren's syndrome in NOD/Ltj mouse." in: Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, Vol. 43, Issue 10, pp. 785-91, (2014) (PubMed).

Nakano, Morimoto, Suzuki, Nozawa, Amano, Tokano, Takasaki: "Role of pathogenic auto-antibody production by Toll-like receptor 9 of B cells in active systemic lupus erythematosus." in: Rheumatology (Oxford, England), Vol. 47, Issue 2, pp. 145-9, (2008) (PubMed).

Meng, Kujas, Marie, Paris, Thillet, Delattre, Carpentier: "Expression of TLR9 within human glioblastoma." in: Journal of neuro-oncology, Vol. 88, Issue 1, pp. 19-25, (2008) (PubMed).

Selleri, Palazzo, Deola, Wang, Balsari, Marincola, Rumio: "Induction of pro-inflammatory programs in enteroendocrine cells by the Toll-like receptor agonists flagellin and bacterial LPS." in: International immunology, Vol. 20, Issue 8, pp. 961-70, (2008) (PubMed).

Meneghin, Choi, Evanoff, Kunkel, Martinez, Flaherty, Toews, Hogaboam: "TLR9 is expressed in idiopathic interstitial pneumonia and its activation promotes in vitro myofibroblast differentiation." in: Histochemistry and cell biology, Vol. 130, Issue 5, pp. 979-92, (2008) (PubMed).

Tran, Koch, Berkels, Boehm, Zacharowski, Baumgarten, Knuefermann, Schott, Kanczkowski, Bornstein, Lightman, Zacharowski: "Toll-like receptor 9 expression in murine and human adrenal glands and possible implications during inflammation." in: The Journal of clinical endocrinology and metabolism, Vol. 92, Issue 7, pp. 2773-83, (2007) (PubMed).

Target Details for TLR9

Target: TLR9 (Toll-Like Receptor 9 (TLR9))

Alternative Name: CD289 / TLR9 (TLR9 Products)

Synonyms: CD289 antibody, toll like receptor 9 antibody, toll-like receptor 9 antibody, TLR9 antibody, Tlr9 antibody

Gene ID: 54106

Pathways: TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades