ASPSCR1 antibody (Alveolar Soft Part Sarcoma Chromosome Region, Candidate 1)

Details for Product anti-ASPSCR1 Antibody No. ABIN967214, Supplier: Log in to see
Antigen
  • tug
  • aspl
  • asps
  • rcc17
  • ubxd9
  • aspcr1
  • ASPCR1
  • ASPL
  • ASPS
  • RCC17
  • TUG
  • UBXD9
  • UBXN9
  • 1190006K01Rik
  • ASPC
  • alveolar soft part sarcoma chromosome region, candidate 1
  • alveolar soft part sarcoma chromosome region, candidate 1 (human)
  • ASPSCR1
  • aspscr1
  • Aspscr1
  • Bm1_55980
Reactivity
Mouse (Murine)
80
50
17
6
1
Host
73
42
Clonality
Monoclonal
Conjugate
This ASPSCR1 antibody is un-conjugated
6
6
6
5
4
4
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
ELISA, Western Blotting (WB)
95
64
13
9
6
4
4
4
2
1
1
1
Options
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Isotype IgG1
Specificity Ni-NTA purified truncated recombinant TUG expressed in E. Coli strain BL21 (DE3)
Purification Antibodies are purified by protein A affinity chromatography
Alternative Name TUG (ASPSCR1 Antibody Abstract)
Background The TUG protein contains a UBX domain, for GLUT4. In truncated form, TUG acts in a dominantnegative manner to inhibit insulin-stimulated GLUT4 redistribution in Chinese hamster ovary cells and 3T3-L1 adipocytes. Full-length TUG forms a complex specifically with GLUT4. In 3T3-L1 adipocytes, this complex is present in unstimulated cells and is largely disassembled by insulin. Endogenous TUG is localized with the insulin-mobilizable pool of GLUT4 in unstimulated 3T3-L1 adipocytes, and is not mobilized to the plasma membrane by insulin.
Gene ID 68938
Research Area Signaling, Metabolism
Application Notes Western Blot: 1: 500- 1: 2,000
ELISA: Propose dilution 1: 10,000.
Determining optimal working dilutions by titration test.
Restrictions For Research Use only
Buffer PBS with 0.2%BSA
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Product cited in: Bogan, Hendon, McKee, Tsao, Lodish: "Functional cloning of TUG as a regulator of GLUT4 glucose transporter trafficking." in: Nature, Vol. 425, Issue 6959, pp. 727-33, 2003 (PubMed).