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VCAM1 antibody

VCAM1 Reactivity: Rat FACS, IP, IHC (fro) Host: Mouse Monoclonal MR106 unconjugated
Catalog No. ABIN967640
  • Target See all VCAM1 Antibodies
    VCAM1 (Vascular Cell Adhesion Molecule 1 (VCAM1))
    Reactivity
    • 106
    • 57
    • 21
    • 11
    • 8
    • 8
    • 4
    • 3
    • 1
    • 1
    Rat
    Host
    • 71
    • 61
    • 28
    • 5
    • 1
    • 1
    Mouse
    Clonality
    • 106
    • 59
    • 1
    Monoclonal
    Conjugate
    • 90
    • 24
    • 21
    • 8
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This VCAM1 antibody is un-conjugated
    Application
    • 80
    • 73
    • 50
    • 39
    • 31
    • 26
    • 16
    • 15
    • 15
    • 8
    • 7
    • 7
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Brand
    BD Pharmingen™
    Characteristics
    1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
    2. Please refer to us for technical protocols.
    3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
    Purification
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    Immunogen
    Rat VCAM-1-transfected L5178Y Cells
    Clone
    MR106
    Isotype
    IgG1 kappa
    Top Product
    Discover our top product VCAM1 Primary Antibody
  • Application Notes
    Caution: Sodium azide is a reversible inhibitor of oxidative metabolism, therefore, antibody preparations containing this preservative agent must not be used in cell cultures nor injected into animals. Sodium azide may be removed by washing stained cells or plate-bound antibody or dialyzing soluble antibody in sodium azide-free buffer. Since endotoxin may also affect the results of functional studies, we recommend the NA/LE™ (No Azide/Low Endotoxin) antibody format for in vitro and in vivo use.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 mg/mL
    Buffer
    Aqueous buffered solution containing ≤0.09 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
    Storage Comment
    Store undiluted at 4°C.
  • Bevilacqua: "Endothelial-leukocyte adhesion molecules." in: Annual review of immunology, Vol. 11, Issue 4, pp. 767-804, (1993) (PubMed).

  • Target
    VCAM1 (Vascular Cell Adhesion Molecule 1 (VCAM1))
    Alternative Name
    CD106 (VCAM1 Products)
    Synonyms
    CD106 antibody, INCAM-100 antibody, Vcam-1 antibody, VCAM1B antibody, fi76d06 antibody, wu:fi76d06 antibody, zgc:158875 antibody, VCAM1 antibody, vascular cell adhesion molecule 1 antibody, vascular cell adhesion molecule 1b antibody, VCAM1 antibody, Vcam1 antibody, vcam1b antibody, VCAM-1 antibody
    Background
    The MR106 antibody reacts with CD106, the ~110 kDa transmembrane vascular cell adhesion molecule-1 (VCAM-1). Expression of CD106 on endothelial cells is induced by inflammatory cytokines and in certain pathologic conditions. In the rat bone marrow, CD106 has been reported to be expressed on dendritic cells and subsets of the myeloid lineage, but not detectable on peripheral leukocytes. CD106 has been reported to be a counter-receptor for VLA-4 (alpha4beta1 integrin) and alpha4beta7 integrin, and it plays an important role in leukocyte extravasation, particularly at sites of inflammation. This antibody is routinely tested by flow cytometric analysis.
    Synonyms: VCAM-1
    Pathways
    Carbohydrate Homeostasis
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