HFE antibody
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- Target See all HFE Antibodies
- HFE (Hemochromatosis (HFE))
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This HFE antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunocytochemistry (ICC)
- Purification
- purified
- Immunogen
- Purified recombinant fragment of human HFE expressed in E. coli.
- Clone
- 3F1
- Isotype
- IgG1
- Top Product
- Discover our top product HFE Primary Antibody
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- Application Notes
- ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: 1:200 - 1:1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Ascitic fluid containing 0.03 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C/-20 °C
- Storage Comment
- 4°C, -20°C for long term storage
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PTEN identified as important risk factor of chronic obstructive pulmonary disease." in: Respiratory medicine, Vol. 103, Issue 12, pp. 1866-70, (2009) (PubMed).
: "HFE mutations modulate the effect of iron on serum hepcidin-25 in chronic hemodialysis patients." in: Clinical journal of the American Society of Nephrology : CJASN, Vol. 4, Issue 8, pp. 1331-7, (2009) (PubMed).
: "
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PTEN identified as important risk factor of chronic obstructive pulmonary disease." in: Respiratory medicine, Vol. 103, Issue 12, pp. 1866-70, (2009) (PubMed).
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- Target
- HFE (Hemochromatosis (HFE))
- Alternative Name
- HFE (HFE Products)
- Synonyms
- HFE1 antibody, HH antibody, HLA-H antibody, MVCD7 antibody, TFQTL2 antibody, MR2 antibody, hemochromatosis antibody, HFE antibody, Hfe antibody
- Background
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Description: The protein encoded by this gene is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in this gene. At least nine alternatively spliced variants have been described for this gene. Additional variants have been found but their full-length nature has not been determined.
Aliases: HH, HFE1, HLA-H, MVCD7, TFQTL2, MGC103790, dJ221C16.10.1
- Molecular Weight
- 40 kDa
- Gene ID
- 3077
- HGNC
- 3077
- Pathways
- Transition Metal Ion Homeostasis, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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