MELK antibody (Maternal Embryonic Leucine Zipper Kinase) (AA 637-651)

Details for Product anti-MELK Antibody No. ABIN969538, Supplier: Log in to see
Antigen
  • MELK
  • xmelk
  • Melk
  • HPK38
  • AI327312
  • MPK38
  • mKIAA0175
  • fb71b01
  • fe01f04
  • wu:fb71b01
  • wu:fe01f04
  • maternal embryonic leucine zipper kinase
  • MELK
  • melk
  • cgd5_2270
  • Melk
Epitope
AA 637-651
37
18
15
14
13
6
6
4
3
2
2
2
1
1
1
1
1
1
1
1
1
Reactivity
Human
135
33
24
7
5
5
5
4
4
3
1
1
1
Host
Mouse
96
26
19
Clonality (Clone)
Monoclonal ()
Conjugate
This MELK antibody is un-conjugated
7
7
7
6
5
5
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunohistochemistry (IHC), ELISA
87
74
26
24
21
19
13
12
4
2
2
1
1
Options
Supplier
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Supplier Product No.
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Immunogen Synthesized peptide of human MELK(AA 637-651C-VYKRLVEDILSSCKV).
Sequence VYKRLVEDIL SSCKV
Clone 2G2
Isotype IgG2a
Purification Purified
Alternative Name MELK (MELK Antibody Abstract)
Background Maternal embryonic leucine-zipper kinase (MELK) is a key regulator of survival of stemlike GBM cells in vitro. MELK expression is increased in breast cancer tissue and this increase is also associated with poor patient survival, as predicted for a candidate oncogene.
Molecular Weight 74.6 kDa
Gene ID 9833
HGNC 9833
Research Area Embryogenesis, Embryonic stem cells, Hormones, Receptors
Application Notes ELISA: 1:10000, IHC: 1:200 - 1:1000, ICC: 1:200 - 1:1000, FCM: 1:200 - 1:400
Restrictions For Research Use only
Format Liquid
Buffer PBS with 0.05 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C,-20 °C
Storage Comment 4°C, -20°C for long term storage
Supplier Images
ELISA image for anti-Maternal Embryonic Leucine Zipper Kinase (MELK) (AA 637-651) antibody (ABIN969538) Figure 1: Red: Control Antigen (100 ng), Purple: Antigen (10ng), Green: Antigen (50 n...
Flow Cytometry (FACS) image for anti-Maternal Embryonic Leucine Zipper Kinase (MELK) (AA 637-651) antibody (ABIN969538) Figure 2: Flow cytometric analysis of MCF-7 cells using MELK mouse mAb (green) and ne...
Immunocytochemistry (ICC) image for anti-Maternal Embryonic Leucine Zipper Kinase (MELK) (AA 637-651) antibody (ABIN969538) Figure 3: Immunofluorescence analysis of HepG2 cells using MELK mouse mAb (green) . B...
Immunohistochemistry (IHC) image for anti-Maternal Embryonic Leucine Zipper Kinase (MELK) (AA 637-651) antibody (ABIN969538) Figure 4: Immunohistochemical analysis of paraffin-embedded liver cancer tissues usin...
Immunohistochemistry (IHC) image for anti-Maternal Embryonic Leucine Zipper Kinase (MELK) (AA 637-651) antibody (ABIN969538) Figure 5: Immunohistochemical analysis of paraffin-embedded rectum cancer tissues usi...
Product cited in: Nakano, Joshi, Visnyei, Hu, Watanabe, Lam, Wexler, Saigusa, Nakamura, Laks, Mischel, Viapiano, Kornblum: "Siomycin A targets brain tumor stem cells partially through a MELK-mediated pathway." in: Neuro-oncology, Vol. 13, Issue 6, pp. 622-34, 2011 (PubMed).

Pickard, Green, Ellis, Caldas, Hedge, Mourtada-Maarabouni, Williams: "Dysregulated expression of Fau and MELK is associated with poor prognosis in breast cancer." in: Breast cancer research : BCR, Vol. 11, Issue 4, pp. R60, 2009 (PubMed).

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