Dopamine Receptor d1 antibody (N-Term)

Catalog No. ABIN970558

Product Details anti-Dopamine Receptor d1 Antibody

Target: Dopamine Receptor d1 (DRD1) (Dopamine Receptor D1 (DRD1))

Binding Specificity: N-Term

Reactivity: Human, Rat, Pig, Cow, Rabbit, Dog, Horse, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Dopamine Receptor d1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: AAFILISVAW TLSVLISFIP VQLSWHKAKP TSPSDGNATS LAETIDNCDS

Predicted Reactivity: Cow: 86%, Dog: 93%, Guinea Pig: 92%, Horse: 86%, Human: 100%, Pig: 93%, Rabbit: 93%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against DRD1. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 446 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Dopamine Receptor d1

Target: Dopamine Receptor d1 (DRD1) (Dopamine Receptor D1 (DRD1))

Alternative Name: DRD1 (DRD1 Products)

Synonyms: DRD1 antibody, Dop1 antibody, D1A antibody, DADR antibody, DRD1A antibody, drd1 antibody, C030036C15Rik antibody, Drd-1 antibody, Drd1 antibody, Gpcr15 antibody, D1a antibody, Drd1a antibody, dopamine receptor D1 antibody, dopamine receptor, D1 antibody, dopamine receptor D1b antibody, DRD1 antibody, Dop1 antibody, drd1b antibody, Drd1 antibody

Background: This gene encodes the D1 subtype of the dopamine receptor. The D1 subtype is the most abundant dopamine receptor in the central nervous system. This G-protein coupled receptor stimulates adenylyl cyclase and activates cyclic AMP-dependent protein kinases. D1 receptors regulate neuronal growth and development, mediate some behavioral responses, and modulate dopamine receptor D2-mediated events.
Alias Symbols: DADR, DRD1A
Protein Interaction Partner: RANBP10, RANBP9, HRH3, GRIN1, DNAJC14, COPG1, EPB41L2, CALY, COPG2, CAV2, FLNA, ADORA1, ADA,
Protein Size: 446

Molecular Weight: 49 kDa

Gene ID: 1812

NCBI Accession: NM_000794, NP_000785

UniProt: P21728

Pathways: cAMP Metabolic Process, Inositol Metabolic Process, Protein targeting to Nucleus, Feeding Behaviour, Smooth Muscle Cell Migration, Regulation of long-term Neuronal Synaptic Plasticity