SHMT1 antibody (N-Term)

Catalog No. ABIN971697

Product Details anti-SHMT1 Antibody

Target: SHMT1 (serine Hydroxymethyltransferase 1 (Soluble) (SHMT1))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Rabbit, Cow, Sheep, Horse, Zebrafish (Danio rerio), Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SHMT1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: NIIKKESNRQ RVGLELIASE NFASRAVLEA LGSCLNNKYS EGYPGQRYYG

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Yeast: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against SHMT1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SHMT1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 483 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SHMT1

Target: SHMT1 (serine Hydroxymethyltransferase 1 (Soluble) (SHMT1))

Alternative Name: SHMT1 (SHMT1 Products)

Synonyms: Shmt antibody, mShmt antibody, LRRGT00032 antibody, shmt1 antibody, MGC53442 antibody, zgc:66171 antibody, zgc:77524 antibody, SHMT1 antibody, Shmt1 antibody, CSHMT antibody, SHMT antibody, AI324848 antibody, AI385541 antibody, C81125 antibody, mshmt antibody, mshmt1 antibody, mshmt2 antibody, MEL-32 antibody, SHMT2 antibody, F20D10.50 antibody, F20D10_50 antibody, SERINE HYDROXYMETHYLTRANSFERASE 1 antibody, SERINE TRANSHYDROXYMETHYLASE antibody, SERINE TRANSHYDROXYMETHYLTRANSFERASE antibody, STM antibody, serine transhydroxymethyltransferase 1 antibody, serine hydroxymethyltransferase 1 antibody, serine hydroxymethyltransferase 1 (soluble) L homeolog antibody, serine hydroxymethyltransferase 1 (soluble) antibody, microRNA 6778 antibody, serine transhydroxymethyltransferase 1 antibody, Shmt1 antibody, shmt1.L antibody, shmt1 antibody, MIR6778 antibody, SHMT1 antibody, SHM1 antibody

Background: This gene encodes the cellular form of serine hydroxymethyltransferase, a pyridoxal phosphate-containing enzyme that catalyzes the reversible conversion of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. This reaction provides one carbon units for synthesis of methionine, thymidylate, and purines in the cytoplasm. This gene is located within the Smith-Magenis syndrome region on chromosome 17. Alternative splicing of this gene results in 2 transcript variants encoding 2 different isoforms. Additional transcript variants have been described, but their biological validity has not been determined.
Alias Symbols: CSHMT, MGC15229, MGC24556, SHMT
Protein Interaction Partner: UBC, SULT1A3, SHMT1, MAPK9, C18orf25, FAM129B, SNX6, XPO5, VPS29, PBDC1, GSPT2, HIST1H4A, CARS, ATP6V1C1, APEH, CTTN, TTC1, TSN, STAT1, SNX2, SHMT2, PAWR, IDE, HARS, GTF2F2, GARS, DEDD, MCAT, ZC3H4, HSPA1L, SUMO1, SUMO2, SUMO3, PRSS23, PIM1, CSNK2B, DLEU1
Protein Size: 483

Molecular Weight: 53 kDa

Gene ID: 6470

NCBI Accession: NM_004169, NP_004160

UniProt: Q5RFK5