SYK antibody (Middle Region)
-
- Target See all SYK Antibodies
- SYK (Spleen tyrosine Kinase (SYK))
-
Binding Specificity
- Middle Region
-
Reactivity
- Human, Pig, Horse
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This SYK antibody is un-conjugated
-
Application
- Western Blotting (WB)
- Sequence
- RIKSYSFPKP GHRKSSPAQG NRQESTVSFN PYEPELAPWA ADKGPQREAL
- Predicted Reactivity
- Horse: 85%, Human: 100%, Pig: 79%
- Characteristics
- This is a rabbit polyclonal antibody against SYK. It was validated on Western Blot.
- Purification
- Affinity Purified
- Top Product
- Discover our top product SYK Primary Antibody
-
-
- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
-
Antigen size: 635 AA
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
- Target
- SYK (Spleen tyrosine Kinase (SYK))
- Alternative Name
- SYK (SYK Products)
- Synonyms
- p72-Syk antibody, Sykb antibody, p72syk antibody, spleen associated tyrosine kinase antibody, spleen tyrosine kinase antibody, syk antibody, SYK antibody, Syk antibody
- Background
-
This gene encodes a member of the family of non-receptor type Tyr protein kinases. This protein is widely expressed in hematopoietic cells and is involved in coupling activated immunoreceptors to downstream signaling events that mediate diverse cellular responses, including proliferation, differentiation, and phagocytosis. It is thought to be a modulator of epithelial cell growth and a potential tumour suppressor in human breast carcinomas. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: DKFZp313N1010, FLJ25043, FLJ37489, p72-Syk
Protein Interaction Partner: SH2D2A, TRAF6, STAT3, USP25, IL17RA, TRAF3IP2, PTPRO, UBC, FCGR3A, TICAM1, TLR9, TBK1, TRAF3, TLR4, TLR3, MAP3K7, MYD88, SRC, SYK, UBASH3B, VCAM1, ITGA4, ERBB4, ERBB3, ERBB2, EGFR, APP, SH3BP2, MAPT, TUBB, VAV2, VAV1, PIK3CG, BLNK, CBL, BTK, PIK3R1, TRAIP
Protein Size: 635 - Molecular Weight
- 72 kDa
- Gene ID
- 6850
- NCBI Accession
- NM_003177, NP_003168
- UniProt
- P43405
- Pathways
- Fc-epsilon Receptor Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Thromboxane A2 Receptor Signaling, BCR Signaling
-