XPA antibody (C-Term)
-
- Target See all XPA Antibodies
- XPA (Xeroderma Pigmentosum, Complementation Group A (XPA))
-
Binding Specificity
- C-Term
-
Reactivity
- Human, Mouse, Rat, Dog, Cow, Pig, Guinea Pig, Horse
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This XPA antibody is un-conjugated
-
Application
- Western Blotting (WB)
- Sequence
- MKQKKFDKKV KELRRAVRSS VWKRETIVHQ HEYGPEENLE DDMYRKTCTM
- Predicted Reactivity
- Cow: 86%, Dog: 100%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%
- Characteristics
- This is a rabbit polyclonal antibody against XPA. It was validated on Western Blot.
- Purification
- Affinity Purified
- Top Product
- Discover our top product XPA Primary Antibody
-
-
- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
-
Antigen size: 273 AA
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
- Target
- XPA (Xeroderma Pigmentosum, Complementation Group A (XPA))
- Alternative Name
- XPA (XPA Products)
- Synonyms
- CG6358 antibody, DhR14 antibody, DhXPA antibody, DmXPA antibody, Dmel\\CG6358 antibody, Dxpa antibody, EG:EG0007.8 antibody, XPAC antibody, XPA_DROME antibody, Xpa antibody, dmXPA antibody, dxpa antibody, XP1 antibody, AI573865 antibody, Xpac antibody, xpac antibody, xxpa antibody, Xeroderma pigmentosum group A-like antibody, XPA, DNA damage recognition and repair factor antibody, xeroderma pigmentosum, complementation group A antibody, xeroderma pigmentosum, complementation group A L homeolog antibody, Xpac antibody, XPA antibody, Xpa antibody, xpa.L antibody
- Background
-
This gene encodes a zinc finger protein involved in DNA excision repair. The encoded protein is part of the NER (nucleotide excision repair) complext which is responsible for repair of UV radiation-induced photoproducts and DNA adducts induced by chemical carcinogens. Mutations in this gene are associated with xeroderma pigmentosum complementation group A. Alternatively spliced transcript variants have been found for this gene.
Alias Symbols: XP1, XPAC
Protein Interaction Partner: NDEL1, TRIM27, HERC2, ATR, PRKDC, ATM, HMGB1, ERCC1, DDB2, DDB1, RPA1, XPC, POLR2A, HHV8GK18_gp81, GTF2H1, ERCC6, RPA2, MSH3, MSH2, XAB2, GPN1, RPA4, RASSF1, GTF2E2, EP300,
Protein Size: 273 - Molecular Weight
- 31 kDa
- Gene ID
- 7507
- NCBI Accession
- NM_000380, NP_000371
- UniProt
- P23025
- Pathways
- DNA Damage Repair
-