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anti-Human Caspase 10 antibody for ELISA

Recommended Caspase 10 Antibody (supplied by: Log in to see )

Antigen
Caspase 10, Apoptosis-Related Cysteine Peptidase (CASP10) Antibodies
  • alps2
  • ALPS2
  • caspace-10
  • caspase-10
  • FLICE2
  • flice2
  • MCH4
  • mch4
  • xCaspace-10
  • xCaspase-10
Epitope
AA 1-111
28
8
5
5
5
4
4
4
3
3
3
3
3
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human
138
20
18
1
Host
Mouse
124
8
3
2
1
Clonality
Monoclonal
Conjugate
This Caspase 10 antibody is un-conjugated
1
1
1
1
1
1
1
1
1
1
1
1
Application
ELISA
110
44
32
21
19
11
8
7
3
2
2
1
1
Supplier
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Catalog No. ABIN393206
$ 450.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.30628014 ABIN514026 IF ELISA WB Mouse IgG2a kappa AA 1-110, partial Log in to see 2E7
0.30628014 ABIN560178 PLA ELISA Mouse IgG1 kappa AA 1-110, partial Log in to see 1D8
0.0012155735 ABIN1533218 IF IHC ELISA WB Rabbit IgG Log in to see Polyclonal
0.0012155735 ABIN1001994 ELISA WB Rabbit IgG C-Term Log in to see Polyclonal 3
0.0012155735 ABIN2879118 IF IHC (p) ELISA WB Rabbit IgG AA 430-479 Log in to see Polyclonal
0.0012155735 ABIN1584152 IHC ELISA WB Rabbit C-Term Log in to see Polyclonal
0.0012155735 ABIN205220 ELISA WB Rabbit IgG N-Term Log in to see Polyclonal
0.0012155735 ABIN219293 ELISA WB Rabbit IgG Asp219 Log in to see Polyclonal
0.0012155735 ABIN2163235 IF IHC ELISA WB Rabbit IgG Log in to see Polyclonal
0.0012155735 ABIN352118 ELISA WB Rabbit IgG AA 169-219 Log in to see Polyclonal
0.0012155735 ABIN352119 ELISA WB Rabbit IgG AA 280-330 Log in to see Polyclonal
0.0012155735 ABIN1838621 ELISA WB Rabbit AA 280-330 Log in to see Polyclonal
0.0012155735 ABIN3187650 ELISA WB Rabbit IgG Internal Region Log in to see Polyclonal
0.0012155735 ABIN514027 IF ELISA WB Mouse IgG2a kappa AA 19-187, partial Log in to see 3C9
0.0012155735 ABIN2156126 ELISA WB Rabbit AA 505-521 Log in to see Polyclonal
0.0012155735 ABIN1584151 IP IHC ELISA WB Rabbit C-Term Log in to see Polyclonal
0.0012155735 ABIN1574050 ELISA WB Rabbit IgG AA 280-330 Log in to see Polyclonal
0.0012155735 ABIN1574071 ELISA WB Rabbit IgG AA 169-219 Log in to see Polyclonal
0.0012155735 ABIN1817070 ELISA WB Rabbit Log in to see Polyclonal
0.0012155735 ABIN560177 ELISA WB Mouse AA 1-110, partial Log in to see Polyclonal

Top referenced anti-Caspase 10 antibody for ELISA

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Application / Reactivity Human
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Enzyme Immunoassay (EIA) 2 Antibodies
Flow Cytometry (FACS) 1 Antibodies
Immunochromatography (IC) 2 Antibodies
Immunocytochemistry (ICC) 10 Antibodies
Immunofluorescence (IF) 23 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 11 Antibodies
Immunohistochemistry (IHC) 34 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 3 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 21 Antibodies
Immunoprecipitation (IP) 8 Antibodies
Intracellular Flow Cytometry (ICFC) 1 Antibodies
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General

Antigen Caspase 10, Apoptosis-Related Cysteine Peptidase (CASP10) Antibodies
Epitope AA 1-111
(28), (8), (5), (5), (5), (4), (4), (4), (3), (3), (3), (3), (3), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human
(138), (20), (18), (1)
Host Mouse
(124), (8), (3), (2), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This Caspase 10 antibody is un-conjugated
(1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application ELISA
(110), (44), (32), (21), (19), (11), (8), (7), (3), (2), (2), (1), (1)
Pubmed 5 references available
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Product Details anti-Caspase 10 Antibody

Target Details Caspase 10 Application Details Handling References for anti-Caspase 10 Antibody (ABIN393206) Images
Specificity CASP10 (NP_116756, 1 a.a. ~ 111 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Immunogen CASP10 (NP_116756, 1 a.a. ~ 111 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 1D8
Isotype IgG1 kappa

Target Details Caspase 10

Product Details anti-Caspase 10 Antibody Application Details Handling References for anti-Caspase 10 Antibody (ABIN393206) Images back to top
Antigen
Alternative Name CASP10 (CASP10 Antibody Abstract)
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight 58951 DA
Gene ID 12406
NCBI Accession NP_116756
Research Area Apoptosis/Necrosis, Cell Structure
Pathways Apoptosis, Caspase Cascade in Apoptosis

Application Details

Product Details anti-Caspase 10 Antibody Target Details Caspase 10 Handling References for anti-Caspase 10 Antibody (ABIN393206) Images back to top
Application Notes ELISA ~~ 1ug/ml~3ng/ml
Comment

Background: This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 3 and 7, and the protein itself is processed by caspase 8. Mutations in this gene are associated with apoptosis defects seen in type II autoimmune lymphoproliferative syndrome. Three alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Restrictions For Research Use only

Handling

Product Details anti-Caspase 10 Antibody Target Details Caspase 10 Application Details References for anti-Caspase 10 Antibody (ABIN393206) Images back to top
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months

References for anti-Caspase 10 Antibody (ABIN393206)

Product Details anti-Caspase 10 Antibody Target Details Caspase 10 Application Details Handling Images back to top
Background publications

Ho-Pun-Cheung, Assenat, Bascoul-Mollevi, Bibeau, Boissière-Michot, Thezenas, Cellier, Azria, Rouanet, Senesse, Ychou, Lopez-Crapez: "A large-scale candidate gene approach identifies SNPs in SOD2 and IL13 as predictive markers of response to preoperative chemoradiation in rectal cancer." in: The pharmacogenomics journal, Vol. 11, Issue 6, pp. 437-43, 2011

Lee, Choi, Choi, Kim, Kim, Jung, Kang, Jeon, Lee, Jin, Cha, Kim, Jung, Park: "Polymorphisms in the caspase genes and the risk of lung cancer." in: Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, Vol. 5, Issue 8, pp. 1152-8, 2010

Liu, Wu, Chen, Ter-Minassian, Asomaning, Zhai, Wang, Su, Heist, Kulke, Lin, Liu, Christiani: "A Large-scale genetic association study of esophageal adenocarcinoma risk." in: Carcinogenesis, Vol. 31, Issue 7, pp. 1259-63, 2010

Kim, Park, Kim, Lee, Lim, Song, Yoo, Lee: "Mutational analysis of caspase genes in prostate carcinomas." in: APMIS : acta pathologica, microbiologica, et immunologica Scandinavica, Vol. 118, Issue 4, pp. 308-12, 2010

Oh, Kim, Ahn, Kim, Han, Lee, Yoo: "Mutational analysis of CASP10 gene in colon, breast, lung and hepatocellular carcinomas." in: Pathology, Vol. 42, Issue 1, pp. 73-6, 2009

Images

Product Details anti-Caspase 10 Antibody Target Details Caspase 10 Application Details Handling References for anti-Caspase 10 Antibody (ABIN393206) back to top
Supplier Images
ELISA image for anti-Caspase 10 antibody (Caspase 10, Apoptosis-Related Cysteine Peptidase) (AA 1-111) (ABIN393206) Detection limit for recombinant GST tagged CASP10 is approximately 0.03 ng/mL as a ca...