anti-Human Caspase 2 antibody for Enzyme Immunoassay

Recommended Caspase 2 Antibody (supplied by: Log in to see )

Antigen
Caspase 2, Apoptosis-Related Cysteine Peptidase (CASP2) Antibodies
  • xCaspase-2
  • Caspase-2
  • ICH-1
  • Nedd2
  • CASP-2
  • ICH1
  • NEDD-2
  • NEDD2
  • PPP1R57
  • ICH-1L/1S
  • ICH1L1S
  • caspase-2-like
  • caspase-2
  • caspase 2
  • caspase 2, apoptosis-related cysteine peptidase
  • LOC100050611
  • xCaspase-2
  • CpipJ_CPIJ008254
  • Casp2
  • LOC100101590
  • CASP2
  • LOC100521118
Epitope
AA 32-169
26
21
14
9
7
5
5
4
4
4
3
3
3
3
3
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human
206
90
69
10
8
2
2
2
2
2
1
1
1
1
1
1
Host
Mouse
154
50
12
Clonality
Monoclonal
Conjugate
This Caspase 2 antibody is un-conjugated
6
6
3
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
176
97
47
33
17
14
13
12
12
4
4
3
2
1
Supplier
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Catalog No. ABIN180742
$ 643.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN5554658 EIA IF WB Rabbit IgG N-Term Log in to see Polyclonal
1 ABIN317792 EIA IHC (p) WB Rabbit Log in to see Polyclonal

Similar anti-Caspase 2 Antibodies

Application / Reactivity Human
BioImaging (BI) 1 Antibodies
ELISA 93 Antibodies
Enzyme Immunoassay (EIA) 3 Antibodies
Flow Cytometry (FACS) 12 Antibodies
Immunochromatography (IC) 4 Antibodies
Immunocytochemistry (ICC) 16 Antibodies
Immunofluorescence (IF) 14 Antibodies
Immunofluorescence (fixed cells) (IF/ICC) 1 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 13 Antibodies
Immunohistochemistry (IHC) 45 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 4 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 32 Antibodies
Immunoprecipitation (IP) 11 Antibodies
Western Blotting (WB) 167 Antibodies

General

Antigen Caspase 2, Apoptosis-Related Cysteine Peptidase (CASP2) Antibodies
Epitope AA 32-169
(26), (21), (14), (9), (7), (5), (5), (4), (4), (4), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human
(206), (90), (69), (10), (8), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Host Mouse
(154), (50), (12)
Clonality (Clone)
Monoclonal   ( )
Conjugate This Caspase 2 antibody is un-conjugated
(6), (6), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Enzyme Immunoassay (EIA), Western Blotting (WB)
(176), (97), (47), (33), (17), (14), (13), (12), (12), (4), (4), (3), (2), (1)
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Product Details anti-Caspase 2 Antibody

Target Details Caspase 2 Application Details Handling Images
Specificity The antibody recognizes human caspase-2. Other specis not tested.
Characteristics Synonyms: CASP-2, CASP2, ICH1, ICH-1 protease, NEDD2, Neural precursor cell expresseddevelopmentally down-regulated protein 2
Purification Protein-G affinity chromatography
Immunogen Recombinant human caspase-2 (32-169 aa) purified from E. coli. Spleen cells from immunised Balb/c mice were fused with cells of the mouse SP2/0myeloma cell line
Clone 1C10
Isotype IgG2b

Target Details Caspase 2

Product Details anti-Caspase 2 Antibody Application Details Handling Images back to top
Antigen
Alternative Name Caspase-2 (CASP2 Antibody Abstract)
Background The caspase family of cystein proteases functions as fundamental effectors in apoptosis. Caspase-2 is required for the permeabilisation of the mitochondria and the resulting amplification of caspase activity, in response to cytotoxic stress. Cytotoxic stress induced proteolytic cleavage of the caspase-2 proenzyme forms an active caspase which cleaves other caspases in a cascade. This leads to the release of cytochrome c and Smac from mitochondria and the translocation of Bax from the cytoplasm to the mitochondria, leading to apoptosis. In adults, caspase-2 is expressed in the placenta, lung, kidney, pancreas and at lower levels in the heart, brain, liver and skeletal muscle.Synonyms: CASP-2, CASP2, ICH-1 protease, ICH1, NEDD2, Neural precursor cell expressed developmentally down-regulated protein 2
Gene ID 835
UniProt P42575
Research Area Apoptosis/Necrosis, Cancer, Autophagy
Pathways Apoptosis, Caspase Cascade in Apoptosis, Neurotrophin Signaling Pathway

Application Details

Product Details anti-Caspase 2 Antibody Target Details Caspase 2 Handling Images back to top
Application Notes ELISA. Western Blot: 1/500 - 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-Caspase 2 Antibody Target Details Caspase 2 Application Details Images back to top
Format Liquid
Concentration 1.0 mg/mL
Buffer PBS, pH 7.4, containing 0.09 % Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment Store at +4 °C or at -20 °C if preferred. This product should be stored undiluted. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf life: one year from despatch.
Expiry Date 12 months

Images

Product Details anti-Caspase 2 Antibody Target Details Caspase 2 Application Details Handling back to top
Supplier Images
Western Blotting (WB) image for anti-Caspase 2 antibody (Caspase 2, Apoptosis-Related Cysteine Peptidase) (AA 32-169) (ABIN180742) anti-Caspase 2, Apoptosis-Related Cysteine Peptidase (CASP2) (AA 32-169) antibody
Western Blotting (WB) image for anti-Caspase 2 antibody (Caspase 2, Apoptosis-Related Cysteine Peptidase) (AA 32-169) (ABIN180742) anti-Caspase 2, Apoptosis-Related Cysteine Peptidase (CASP2) (AA 32-169) antibody (Image 2)