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anti-Human Caspase 2 antibody for Flow Cytometry

Recommended Caspase 2 Antibody (supplied by: Log in to see )

Antigen
Caspase 2, Apoptosis-Related Cysteine Peptidase (CASP2) Antibodies
  • CASP-2
  • Caspase-2
  • ICH-1
  • ICH-1L/1S
  • ICH1
  • ICH1L1S
  • NEDD-2
  • Nedd2
  • NEDD2
  • PPP1R57
  • xCaspase-2
Epitope
AA 198-226, Center
24
15
12
9
6
5
4
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
Reactivity
Human
178
61
44
6
2
2
Host
Rabbit
154
33
11
Clonality
Polyclonal
Conjugate
This Caspase 2 antibody is un-conjugated
5
5
2
1
1
1
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
154
81
40
28
11
11
10
10
8
7
4
4
1
1
Supplier
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Catalog No. ABIN388122
$ 324.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.3068567 ABIN2158050 FACS IHC ELISA WB Rabbit Ig Fraction Log in to see Polyclonal
0.0010666476 ABIN189199 FACS WB Rabbit IgG N-Term Log in to see Y61
0.0010666476 ABIN187543 FACS IHC (fro) IF Rat IgG2a Log in to see 10C6
0.0010666476 ABIN198454 ICC FACS IHC (fro) ELISA Rat IgG2a Log in to see
0.0010666476 ABIN2617929 ICC IHC (fro) FACS ELISA Rat IgG2a, kappa Log in to see 10C6
0.0010666476 ABIN1841065 FACS IHC (p) WB Rabbit Internal Region Log in to see Polyclonal
0.0010666476 ABIN2218995 IC FACS IHC ELISA Rat IgG2a Log in to see 6D216
0.0010666476 ABIN3030295 FACS IHC ELISA WB Rabbit Ig Fraction AA 198-226 Log in to see Polyclonal
0.0010666476 ABIN2798097 FACS IHC WB Rabbit Ig Fraction Center Log in to see Polyclonal

Top referenced anti-Caspase 2 antibody for Flow Cytometry

Similar anti-Caspase 2 Antibodies

Application / Reactivity Human
BioImaging (BI) 1 Antibodies
ELISA 74 Antibodies
Enzyme Immunoassay (EIA) 3 Antibodies
Flow Cytometry (FACS) 10 Antibodies
Immunochromatography (IC) 4 Antibodies
Immunocytochemistry (ICC) 10 Antibodies
Immunofluorescence (IF) 10 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 11 Antibodies
Immunohistochemistry (IHC) 40 Antibodies
Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp)) 1 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 6 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 26 Antibodies
Immunoprecipitation (IP) 10 Antibodies
Western Blotting (WB) 139 Antibodies

General

Antigen Caspase 2, Apoptosis-Related Cysteine Peptidase (CASP2) Antibodies
Epitope AA 198-226, Center
(24), (15), (12), (9), (6), (5), (4), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human
(178), (61), (44), (6), (2), (2)
Host Rabbit
(154), (33), (11)
Clonality (Clone)
Polyclonal   ( )
Conjugate This Caspase 2 antibody is un-conjugated
(5), (5), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(154), (81), (40), (28), (11), (11), (10), (10), (8), (7), (4), (4), (1), (1)
Pubmed 3 references available
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Product Details anti-Caspase 2 Antibody

Target Details Caspase 2 Application Details Handling References for anti-Caspase 2 Antibody (ABIN388122) Images
Specificity This CASP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 205~234 amino acids from the Center region of human CASP2.
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Immunogen This CASP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 198-226 AA from the Central region of human CASP2.
Clone RB18402
Isotype Ig

Target Details Caspase 2

Product Details anti-Caspase 2 Antibody Application Details Handling References for anti-Caspase 2 Antibody (ABIN388122) Images back to top
Antigen
Alternative Name CASP2 (CASP2 Antibody Abstract)
Background CASP2 is a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. The protein exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The proteolytic cleavage of this protein is induced by a variety of apoptotic stimuli.
Synonyms: Caspase-2, CASP-2, ICH-1 protease, Neural precursor cell expressed developmentally down-regulated protein 2, NEDD-2, Caspase-2 subunit p18, Caspase-2 subunit p13, Caspase-2 subunit p12
Molecular Weight 50685 DA
Gene ID 835
UniProt P42575
Research Area Apoptosis/Necrosis
Pathways Apoptosis, Caspase Cascade in Apoptosis, Neurotrophin Signaling Pathway

Application Details

Product Details anti-Caspase 2 Antibody Target Details Caspase 2 Handling References for anti-Caspase 2 Antibody (ABIN388122) Images back to top
Application Notes WB = 1:1000, IHC (p) = 1:10-50, FACS = 1:10-50
Restrictions For Research Use only

Handling

Product Details anti-Caspase 2 Antibody Target Details Caspase 2 Application Details References for anti-Caspase 2 Antibody (ABIN388122) Images back to top
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months

References for anti-Caspase 2 Antibody (ABIN388122)

Product Details anti-Caspase 2 Antibody Target Details Caspase 2 Application Details Handling Images back to top
Background publications

Shi, Vivian, Lee, Ge, Morotomi-Yano, Manzl, Bock, Sato, Tomomori-Sato, Zhu, Haug, Swanson, Washburn, Chen, Chen, Villunger, Florens, Du: "DNA-PKcs-PIDDosome: a nuclear caspase-2-activating complex with role in G2/M checkpoint maintenance." in: Cell, Vol. 136, Issue 3, pp. 508-20, 2009

Paroni, Henderson, Schneider, Brancolini: "Caspase-2-induced apoptosis is dependent on caspase-9, but its processing during UV- or tumor necrosis factor-dependent cell death requires caspase-3." in: The Journal of biological chemistry, Vol. 276, Issue 24, pp. 21907-15, 2001

Tiso, Pallavicini, Muraro, Zimbello, Apolloni, Valle, Lanfranchi, Danieli: "Chromosomal localization of the human genes, CPP32, Mch2, Mch3, and Ich-1, involved in cellular apoptosis." in: Biochemical and biophysical research communications, Vol. 225, Issue 3, pp. 983-9, 1996

Images

Product Details anti-Caspase 2 Antibody Target Details Caspase 2 Application Details Handling References for anti-Caspase 2 Antibody (ABIN388122) back to top
Supplier Images
Western Blotting (WB) image for anti-Caspase 2 antibody (Caspase 2, Apoptosis-Related Cysteine Peptidase) (AA 198-226) (ABIN388122) Western blot analysis of CASP2 antibody (Center) (ABIN388122) in HL60, K562, Ramos an...
Immunohistochemistry (IHC) image for anti-Caspase 2 antibody (Caspase 2, Apoptosis-Related Cysteine Peptidase) (AA 198-226) (ABIN388122) Formalin-fixed and paraffin-embedded human lung with CASP2 Antibody (Center), which w...
Flow Cytometry (FACS) image for anti-Caspase 2 antibody (Caspase 2, Apoptosis-Related Cysteine Peptidase) (AA 198-226) (ABIN388122) CASP2 Antibody (Center) (ABIN388122) flow cytometric analysis of HL60 cells (bottom h...