You are viewing an incomplete version of our website. Please click to reload the website as full version.

anti-Mouse (Murine) Caspase 2 antibody for Immunofluorescence

Recommended Caspase 2 Antibody (supplied by: Log in to see )

Antigen
Caspase 2, Apoptosis-Related Cysteine Peptidase (CASP2) Antibodies
  • CASP-2
  • Caspase-2
  • ICH-1
  • ICH-1L/1S
  • ICH1
  • ICH1L1S
  • NEDD-2
  • Nedd2
  • NEDD2
  • PPP1R57
  • xCaspase-2
Epitope
N-Term
27
25
15
12
6
6
4
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine)
202
63
46
6
2
2
Host
Rabbit
159
53
11
Clonality
Polyclonal
Conjugate
This Caspase 2 antibody is un-conjugated
6
6
3
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Immunofluorescence (IF), Western Blotting (WB)
178
102
41
30
13
11
11
10
9
7
4
3
1
1
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

It's quick and easy to submit your validation proposal. I want to validate this product

Learn more

Available images

Catalog No. ABIN499559
$ 401.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0010838193 ABIN303201 IF IHC (p) WB Rabbit N-Term Log in to see Polyclonal
0.0010838193 ABIN187543 FACS IHC (fro) IF Rat IgG2a Log in to see 10C6
0.0010838193 ABIN4288071 ELISA ICC IF WB Rabbit N-Term Log in to see Polyclonal

Top referenced anti-Caspase 2 antibody for Immunofluorescence

Similar anti-Caspase 2 Antibodies

Application / Reactivity Mouse (Murine) Human
ELISA 18 Antibodies 94 Antibodies
Enzyme Immunoassay (EIA) 2 Antibodies 3 Antibodies
Flow Cytometry (FACS) 1 Antibodies 10 Antibodies
Immunocytochemistry (ICC) 7 Antibodies 12 Antibodies
Immunofluorescence (IF) 4 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 11 Antibodies
Immunohistochemistry (IHC) 6 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 3 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 12 Antibodies
Immunoprecipitation (IP) 4 Antibodies
Western Blotting (WB) 48 Antibodies
BioImaging (BI) 1 Antibodies
Immunochromatography (IC) 4 Antibodies

General

Antigen Caspase 2, Apoptosis-Related Cysteine Peptidase (CASP2) Antibodies
Epitope N-Term
(27), (25), (15), (12), (6), (6), (4), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine)
(202), (63), (46), (6), (2), (2)
Host Rabbit
(159), (53), (11)
Clonality
Polyclonal
Conjugate This Caspase 2 antibody is un-conjugated
(6), (6), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Enzyme Immunoassay (EIA), Immunofluorescence (IF), Western Blotting (WB)
(178), (102), (41), (30), (13), (11), (11), (10), (9), (7), (4), (3), (1), (1)
Pubmed 4 references available
Supplier Log in to see

Product Details anti-Caspase 2 Antibody

Target Details Caspase 2 Application Details Handling References for anti-Caspase 2 Antibody (ABIN499559) Images
Specificity Caspase-2 antibody was raised against a 16 amino acid peptide from the amino-terminus of human Caspase-2.
Purification Affinity chromatography purified via peptide column
Immunogen Murine Casp-2 / ICH-1 / Nedd2 (N-Terminus) Peptide
Isotype IgG

Target Details Caspase 2

Product Details anti-Caspase 2 Antibody Application Details Handling References for anti-Caspase 2 Antibody (ABIN499559) Images back to top
Antigen
Alternative Name Caspase-2 (CASP2 Antibody Abstract)
Background Caspases are a family of cysteine proteases that can be divided into the apoptotic and inflammatory caspase subfamilies. Unlike the apoptotic caspases, members of the inflammatory subfamily are generally not involved in cell death but are associated with the immune response to microbial pathogens (reviewed in 1 and 2). Members of this subfamily include caspase-1, -4, -5, and -12 and can activate proinflammatory cytokines such as IL-1beta and IL-18 (3,4). Although phylogenetically similar to this subfamily, Caspase-2 is thought to be involved in stress-induced apoptosis (5). Caspase-2 has two major isoforms, overexpression on the long form results in apoptosis while that of the short form suppresses cell death (6).Synonyms: CASP-2, CASP2, ICH-1 protease, ICH1, NEDD2, Neural precursor cell expressed developmentally down-regulated protein 2
Gene ID 835
UniProt P42575
Research Area Apoptosis/Necrosis, Cancer, Autophagy
Pathways Apoptosis, Caspase Cascade in Apoptosis, Neurotrophin Signaling Pathway

Application Details

Product Details anti-Caspase 2 Antibody Target Details Caspase 2 Handling References for anti-Caspase 2 Antibody (ABIN499559) Images back to top
Application Notes ELISA. Western Blot: Caspase-2 antibody can be used for the detection of caspase-2 at 1 μg/mL. Depending on cell lines or tissues used, other cleavage products may be observed. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-Caspase 2 Antibody Target Details Caspase 2 Application Details References for anti-Caspase 2 Antibody (ABIN499559) Images back to top
Buffer PBS containing 0.02 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment Store the antibody undiluted at 2-8 °C.

References for anti-Caspase 2 Antibody (ABIN499559)

Product Details anti-Caspase 2 Antibody Target Details Caspase 2 Application Details Handling Images back to top
Background publications

Zhivotovsky, Orrenius: "Caspase-2 function in response to DNA damage." in: Biochemical and biophysical research communications, Vol. 331, Issue 3, pp. 859-67, 2005

Martinon, Tschopp: "Inflammatory caspases: linking an intracellular innate immune system to autoinflammatory diseases." in: Cell, Vol. 117, Issue 5, pp. 561-74, 2004

Gracie, Robertson, McInnes: "Interleukin-18." in: Journal of leukocyte biology, Vol. 73, Issue 2, pp. 213-24, 2003

Kuida, Lippke, Ku, Harding, Livingston, Su, Flavell: "Altered cytokine export and apoptosis in mice deficient in interleukin-1 beta converting enzyme." in: Science (New York, N.Y.), Vol. 267, Issue 5206, pp. 2000-3, 1995

Images

Product Details anti-Caspase 2 Antibody Target Details Caspase 2 Application Details Handling References for anti-Caspase 2 Antibody (ABIN499559) back to top
Supplier Images
Immunofluorescence (IF) image for anti-Caspase 2 antibody (Caspase 2, Apoptosis-Related Cysteine Peptidase) (N-Term) (ABIN499559) Immunocytochemistry of caspase-2 in A-20 cells with AP30196PU-N caspase-2 antibody at...
Western Blotting (WB) image for anti-Caspase 2 antibody (Caspase 2, Apoptosis-Related Cysteine Peptidase) (N-Term) (ABIN499559) Western blot analysis of caspase-2 in Ramos cells with AP30196PU-N caspase-2 antibody...