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anti-Mouse (Murine) Caspase 6 antibody for Enzyme Immunoassay

Recommended Caspase 6 Antibody (supplied by: Log in to see )

Antigen
Caspase 6, Apoptosis-Related Cysteine Peptidase (CASP6) Antibodies
  • casp6
  • CASP6
  • caspase-6
  • mCASP-6
  • MCH2
  • Mch2
  • mch2
  • xCaspase-6
  • zgc:112960
Epitope
C-Term
56
38
34
17
16
15
13
13
11
6
6
5
5
4
4
3
3
3
3
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine)
268
82
77
15
3
2
1
Host
Rabbit
265
19
16
Clonality
Polyclonal
Conjugate
This Caspase 6 antibody is un-conjugated
18
17
13
10
10
10
3
3
3
3
3
3
3
3
3
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
245
146
111
56
34
27
25
13
10
6
4
1
1
Supplier
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Catalog No. ABIN356823
$ 401.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0008870071 ABIN372895 EIA IHC (p) WB Rabbit IgG Cleavage Site Log in to see Polyclonal

Top referenced anti-Caspase 6 antibody for Enzyme Immunoassay

Similar anti-Caspase 6 Antibodies

Application / Reactivity Mouse (Murine) Human
ELISA 26 Antibodies 127 Antibodies
Enzyme Immunoassay (EIA) 2 Antibodies 5 Antibodies
Flow Cytometry (FACS) 2 Antibodies 2 Antibodies
Immunochromatography (IC) 1 Antibodies 6 Antibodies
Immunocytochemistry (ICC) 5 Antibodies 24 Antibodies
Immunofluorescence (IF) 14 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 22 Antibodies
Immunohistochemistry (IHC) 35 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 3 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 19 Antibodies
Immunoprecipitation (IP) 5 Antibodies
Western Blotting (WB) 56 Antibodies

General

Antigen Caspase 6, Apoptosis-Related Cysteine Peptidase (CASP6) Antibodies
Epitope C-Term
(56), (38), (34), (17), (16), (15), (13), (13), (11), (6), (6), (5), (5), (4), (4), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine)
(268), (82), (77), (15), (3), (2), (1)
Host Rabbit
(265), (19), (16)
Clonality
Polyclonal
Conjugate This Caspase 6 antibody is un-conjugated
(18), (17), (13), (10), (10), (10), (3), (3), (3), (3), (3), (3), (3), (3), (3)
Application Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(245), (146), (111), (56), (34), (27), (25), (13), (10), (6), (4), (1), (1)
Pubmed 5 references available
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Product Details anti-Caspase 6 Antibody

Target Details Caspase 6 Application Details Handling References for anti-Caspase 6 Antibody (ABIN356823) Images
Specificity This antibody is specific to Caspase-6 (C-term).
Purification Protein A Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Immunogen This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human CASP6.
Isotype Ig

Target Details Caspase 6

Product Details anti-Caspase 6 Antibody Application Details Handling References for anti-Caspase 6 Antibody (ABIN356823) Images back to top
Antigen
Alternative Name Caspase-6 (CASP6 Antibody Abstract)
Background CASP6 is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme. This protein could be processed by caspases 7, 8 and 10, and is thought to function as a downstream enzyme in the caspase activation cascade.Synonyms: Apoptotic protease Mch-2, CASP-6, CASP6, MCH-2, MCH2
Gene ID 839, 9606
UniProt P55212
Research Area Apoptosis/Necrosis
Pathways Apoptosis, Caspase Cascade in Apoptosis

Application Details

Product Details anti-Caspase 6 Antibody Target Details Caspase 6 Handling References for anti-Caspase 6 Antibody (ABIN356823) Images back to top
Application Notes ELISA: 1/1,000. Western blot: 1/50-1/100. Immunohistochemistry: 1/10-1/50.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-Caspase 6 Antibody Target Details Caspase 6 Application Details References for anti-Caspase 6 Antibody (ABIN356823) Images back to top
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09 % (W/V) Sodium Azide as preservative.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

References for anti-Caspase 6 Antibody (ABIN356823)

Product Details anti-Caspase 6 Antibody Target Details Caspase 6 Application Details Handling Images back to top
Background publications

Schmeck, Gross, NGuessan, Hocke, Hammerschmidt, Mitchell, Rosseau, Suttorp, Hippenstiel: "Streptococcus pneumoniae-induced caspase 6-dependent apoptosis in lung epithelium." in: Infection and immunity, Vol. 72, Issue 9, pp. 4940-7, 2004

Méndez, Salas-Ocampo, Arias: "Caspases mediate processing of the capsid precursor and cell release of human astroviruses." in: Journal of virology, Vol. 78, Issue 16, pp. 8601-8, 2004

MacLachlan, El-Deiry: "Apoptotic threshold is lowered by p53 transactivation of caspase-6." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 14, pp. 9492-7, 2002

Sordet, Rébé, Dubrez-Daloz, Boudard, Solary: "Intracellular redistribution of procaspases during TPA-induced differentiation of U937 human leukemic cells." in: Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K, Vol. 16, Issue 8, pp. 1569-70, 2002

LeBlanc, Liu, Goodyer, Bergeron, Hammond: "Caspase-6 role in apoptosis of human neurons, amyloidogenesis, and Alzheimer's disease." in: The Journal of biological chemistry, Vol. 274, Issue 33, pp. 23426-36, 1999

Images

Product Details anti-Caspase 6 Antibody Target Details Caspase 6 Application Details Handling References for anti-Caspase 6 Antibody (ABIN356823) back to top
Supplier Images
 image for anti-Caspase 6 antibody (Caspase 6, Apoptosis-Related Cysteine Peptidase) (C-Term) (ABIN356823) anti-Caspase 6, Apoptosis-Related Cysteine Peptidase (CASP6) (C-Term) antibody
 image for anti-Caspase 6 antibody (Caspase 6, Apoptosis-Related Cysteine Peptidase) (C-Term) (ABIN356823) anti-Caspase 6, Apoptosis-Related Cysteine Peptidase (CASP6) (C-Term) antibody (Image 2)