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anti-Cow (Bovine) Caspase 8 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended Caspase 8 Antibody (supplied by: Log in to see )

Antigen
Caspase 8, Apoptosis-Related Cysteine Peptidase (CASP8) Antibodies
  • ALPS2B
  • CAP4
  • Casp-8
  • CASP-8
  • casp8
  • CASP8
  • casp8-A
  • caspase-8
  • FLICE
  • MACH
  • Mch5
  • MCH5
  • xCaspase-8
  • zgc:92075
Reactivity
Cow (Bovine), Human, Monkey, Mouse (Murine)
290
90
64
16
12
4
1
1
1
Host
Rabbit
258
65
11
2
Clonality
Polyclonal
Conjugate
This Caspase 8 antibody is un-conjugated
16
11
6
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Western Blotting (WB)
275
111
71
43
38
26
19
16
11
10
8
5
2
2
1
1
1
1
1
Supplier
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Catalog No. ABIN372513
$ 500.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.00089488085 ABIN1077918 ICC IHC (fro) IHC (p) ELISA WB Rabbit IgG AA 25-175 Log in to see Polyclonal
0.00089488085 ABIN3201520 ICC IHC (fro) IHC (p) ELISA WB Mouse IgG AA 25-175 Log in to see
0.00089488085 ABIN1732676 IHC (p) IP WB Rabbit IgG Log in to see Polyclonal

Similar anti-Caspase 8 Antibodies

Application / Reactivity Human Monkey Cow (Bovine) Mouse (Murine)
Western Blotting (WB) 248 Antibodies 11 Antibodies 12 Antibodies 73 Antibodies
Immunostaining (ISt) 1 Antibodies
Immunoprecipitation (IP) 41 Antibodies 5 Antibodies 3 Antibodies 3 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 42 Antibodies 3 Antibodies 4 Antibodies 13 Antibodies
Immunohistochemistry (IHC) 67 Antibodies 5 Antibodies 4 Antibodies 26 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 4 Antibodies 3 Antibodies 2 Antibodies

General

Antigen Caspase 8, Apoptosis-Related Cysteine Peptidase (CASP8) Antibodies
Reactivity Cow (Bovine), Human, Monkey, Mouse (Murine)
(290), (90), (64), (16), (12), (4), (1), (1), (1)
Host Rabbit
(258), (65), (11), (2)
Clonality
Polyclonal
Conjugate This Caspase 8 antibody is un-conjugated
(16), (11), (6), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Western Blotting (WB)
(275), (111), (71), (43), (38), (26), (19), (16), (11), (10), (8), (5), (2), (2), (1), (1), (1), (1), (1)
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Product Details anti-Caspase 8 Antibody

Target Details Caspase 8 Application Details Handling Images
Specificity Detects the processed forms (42/44 kDa, 24 kDaA and 14 kDa) of Caspase 8. It is the antibody of choice for Immunoprecipitation.
Cross-Reactivity (Details) Species reactivity (expected):Bovine, Monkey, Mouse and Rat.
Species reactivity (tested):Human.
Purification Protein A Chromatography.
Immunogen Recombinant full length Human Caspase 8 protein.
Isotype IgG

Target Details Caspase 8

Product Details anti-Caspase 8 Antibody Application Details Handling Images back to top
Antigen
Alternative Name Caspase-8 (CASP8 Antibody Abstract)
Background Caspases are cysteine proteases, expressed as inactive precursors, that mediate apoptosis by proteolysis of specific substrates. Caspases have the ability to cleave after aspartic acid residues. There are two classes of caspases involved in apoptosis, initiators (activation by receptor cluster) and effectors (activation by mitochondrial permeability transition). Proapoptotic signals autocatalytically activate initiator caspases, such as Caspase 8 and Caspase 9. Activated initiator caspases then process effector caspases, such as Caspase 3 and Caspase 7, which in turn cause cell collapse.Synonyms: Apoptotic cysteine protease, Apoptotic protease Mch-5, CAP4, CASP-8, CASP8, FADD-homologous ICE/CED-3-like protease, FADD-like ICE, ICE-like apoptotic protease 5, MCH5, MORT1-associated CED-3 homolog
Gene ID 841
NCBI Accession NP_001073593
UniProt Q14790
Research Area Apoptosis/Necrosis
Pathways Apoptosis, Caspase Cascade in Apoptosis, TLR Signaling

Application Details

Product Details anti-Caspase 8 Antibody Target Details Caspase 8 Handling Images back to top
Application Notes Western blot. Immunoprecipitation. Immunohistochemistry on Paraffin Sections: 5 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-Caspase 8 Antibody Target Details Caspase 8 Application Details Images back to top
Format Liquid
Buffer 10 mM PBS, pH 7.4 without additives.
Preservative Without preservative
Handling Advice Avoid repeated freezing and thawing.
Storage -20 °C
Storage Comment Store the antibody (in aliquots) at-20 °C for Short term or (Add 40-50% Glycerol) at -70 °C for Long term.

Images

Product Details anti-Caspase 8 Antibody Target Details Caspase 8 Application Details Handling back to top
Supplier Images
 image for anti-Caspase 8 antibody (Caspase 8, Apoptosis-Related Cysteine Peptidase) (ABIN372513) anti-Caspase 8, Apoptosis-Related Cysteine Peptidase (CASP8) antibody