You are viewing an incomplete version of our website. Please click to reload the website as full version.

anti-Dog (Canine) Caspase 8 antibody for ELISA

Recommended Caspase 8 Antibody (supplied by: Log in to see )

Antigen
Caspase 8, Apoptosis-Related Cysteine Peptidase (CASP8) Antibodies
  • ALPS2B
  • CAP4
  • Casp-8
  • CASP-8
  • casp8
  • CASP8
  • casp8-A
  • caspase-8
  • FLICE
  • MACH
  • Mch5
  • MCH5
  • xCaspase-8
  • zgc:92075
Epitope
C-Term
47
18
17
17
13
10
10
8
8
7
7
6
6
5
5
5
4
4
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus), Hamster, Dog (Canine), Cow (Bovine)
339
95
68
18
17
14
4
1
Host
Rabbit
271
101
11
2
Clonality
Polyclonal
Conjugate
This Caspase 8 antibody is un-conjugated
17
12
8
4
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
323
112
80
70
42
34
31
24
12
11
8
5
2
2
1
1
1
1
1
1
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

It's quick and easy to submit your validation proposal. I want to validate this product

Learn more

Catalog No. ABIN1585723
$ 359.70
Plus shipping costs $45.00

Similar anti-Caspase 8 Antibodies

Application / Reactivity Human Cow (Bovine) Mouse (Murine) Rat (Rattus) Hamster Dog (Canine)
Western Blotting (WB) 296 Antibodies 12 Antibodies 77 Antibodies 55 Antibodies 1 Antibodies 1 Antibodies
Immunostaining (ISt) 1 Antibodies
Immunoprecipitation (IP) 44 Antibodies 7 Antibodies 3 Antibodies 6 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 68 Antibodies 5 Antibodies 17 Antibodies 14 Antibodies
Immunohistochemistry (IHC) 77 Antibodies 6 Antibodies 31 Antibodies 29 Antibodies 1 Antibodies

General

Antigen Caspase 8, Apoptosis-Related Cysteine Peptidase (CASP8) Antibodies
Epitope C-Term
(47), (18), (17), (17), (13), (10), (10), (8), (8), (7), (7), (6), (6), (5), (5), (5), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus), Hamster, Dog (Canine), Cow (Bovine)
(339), (95), (68), (18), (17), (14), (4), (1)
Host Rabbit
(271), (101), (11), (2)
Clonality
Polyclonal
Conjugate This Caspase 8 antibody is un-conjugated
(17), (12), (8), (4), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
(323), (112), (80), (70), (42), (34), (31), (24), (12), (11), (8), (5), (2), (2), (1), (1), (1), (1), (1), (1)
Supplier Log in to see

Product Details anti-Caspase 8 Antibody

Target Details Caspase 8 Application Details Handling Images
Cross-Reactivity Mouse (Murine), Rat (Rattus), Hamster, Dog (Canine), Cow (Bovine)
Purification Antibody was purified by Protein-G affinity chromatography.
Immunogen KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of rodent Caspase-8.

Target Details Caspase 8

Product Details anti-Caspase 8 Antibody Application Details Handling Images back to top
Antigen
Alternative Name Caspase-8 (CASP8 Antibody Abstract)
Background Caspase-8 is the most upstream protease of the activation cascade of caspases responsible for the TNFRSF6/FAS mediated and TNFRSF1A induced cell death. Caspase-8 binding to the adapter molecule FADD recruits the complex to either receptor. The resulting aggregate called death-inducing signaling complex (DISC) triggers caspase-8 proteolytic activation. The active dimeric enzyme is then liberated from the DISC and free to activate downstream apoptotic proteases. The enzyme then cleaves and activates caspase-3, caspase-4, caspase-6, caspase-7, caspase-9 and caspase-10. Granzyme B and CPP32 cleave caspase-8 at Asp 315 and Asp 330 respectively to generate the two active subunits.
UniProt Q14790
Research Area Apoptosis/Necrosis
Pathways Apoptosis, Caspase Cascade in Apoptosis, TLR Signaling

Application Details

Product Details anti-Caspase 8 Antibody Target Details Caspase 8 Handling Images back to top
Application Notes ELISA: 1:500-1:1.000, WB: 1:200-1:500, IHC: 1:200-1:500
Restrictions For Research Use only

Handling

Product Details anti-Caspase 8 Antibody Target Details Caspase 8 Application Details Images back to top
Format Liquid
Concentration 1 mg/mL
Buffer Each vial contains 0.1 mg IgG in 0.1 mL of PBS pH7.4 with 0.09% sodium azide.
Preservative Sodium azide
Precaution of Use Warning: This product contains sodium azide, which has been classified as Xn (Harmful), in European Directive 67/548/EEC in the concentration range of 0.1 - 1.0 %. When disposing of this reagent through lead or copper plumbing, flush with copious volumes of water to prevent azide build-up in drains.
Handling Advice Minimize freeze-thaw cycles.
Storage -20°C
Expiry Date 12 months