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Browse our Caspase 8 (CASP8) ELISA Kits

Full name:
Caspase 8, Apoptosis-Related Cysteine Peptidase ELISA Kits (CASP8)
On are 64 Caspase 8, Apoptosis-Related Cysteine Peptidase (CASP8) ELISA Kits from 17 different suppliers available. Additionally we are shipping Caspase 8 Antibodies (337) and Caspase 8 Proteins (24) and many more products for this protein. A total of 447 Caspase 8 products are currently listed.
ALPS2B, CAP4, Casp-8, CASP8, casp8-A, caspase-8, FLICE, MACH, MCH5, xCaspase-8, zgc:92075
list all ELISA KIts Gene Name GeneID UniProt
CASP8 12370 O89110
CASP8 64044  
CASP8 841 Q14790

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Top referenced Caspase 8 ELISA Kits

  1. ABIN411865 : Patil, Kim, Jayaprakasha: Berberine induces apoptosis in breast cancer cells (MCF-7) through mitochondrial-dependent pathway. in European journal of pharmacology 2010 (PubMed)
    Show all 35 references for ABIN411865

  2. ABIN412031 : Anginot, Espeli, Chasson, Mancini, Schiff: Galectin 1 modulates plasma cell homeostasis and regulates the humoral immune response. in Journal of immunology (Baltimore, Md. : 1950) 2013 (PubMed)
    Show all 16 references for ABIN412031

  3. ABIN411861 : Patel, Wilson, ODea, Takata: TNF-induced death signaling triggers alveolar epithelial dysfunction in acute lung injury. in Journal of immunology (Baltimore, Md. : 1950) 2013 (PubMed)
    Show all 11 references for ABIN411861

  4. Rat (Rattus) Caspase 8 ELISA Kit for Sandwich ELISA - ABIN416145 : Abdelkader, Safar, Salem: Ursodeoxycholic Acid Ameliorates Apoptotic Cascade in the Rotenone Model of Parkinson's Disease: Modulation of Mitochondrial Perturbations. in Molecular neurobiology 2015 (PubMed)

More ELISA Kits for Caspase 8 Interaction Partners

Xenopus laevis Caspase 8, Apoptosis-Related Cysteine Peptidase (CASP8) interaction partners

  1. Furthermore, while activities to process procaspase-8 and procaspase-9 appeared in SAMDC (show AMD1 ELISA Kits)-overexpressed apoptotic embryos, the activity to process procaspase-8 did not appear in p53 (show TP53 ELISA Kits)-overexpressed apoptotic embryos.

  2. tail regression at metamorphosis implicates an apoptotic pathway inducible by T(3) hormone in an organ autonomous manner and involving the cell death executioners BH3 interacting domain death agonist (show BID ELISA Kits) and Caspases-2 and -8

Mouse (Murine) Caspase 8, Apoptosis-Related Cysteine Peptidase (CASP8) interaction partners

  1. studies have uncovered the combined actions of the NLRP3 inflammasome and caspase 8 leading to IL-1beta maturation and the directionality of IL-1beta in driving disease inPstpip2(cmo)mice.

  2. Chronic TLR Stimulation Controls NLRP3 (show NLRP3 ELISA Kits) Inflammasome Activation through IL-10 (show IL10 ELISA Kits) Mediated Regulation of NLRP3 (show NLRP3 ELISA Kits) Expression and Caspase-8 Activation

  3. A20 targets caspase-8 and FADD to protect HTLV-I-infected cells.

  4. Data indicate that receptor-interacting serine-threonine kinase 3 (RIPK3 (show RIPK3 ELISA Kits)) deletion prevents inflammatory phenotypes in CreLysM (lysozyme (show LYZ ELISA Kits) M) Casp8fl/fl (caspase 8) mice.

  5. CASP8 deletion did not affect the overall number of microglia expressing the pan specific microglia marker, Iba1 (show AIF1 ELISA Kits)

  6. We observed that NDMP generation was dependent on the extrinsic caspase (show CASP3 ELISA Kits) apoptotic pathway (caspase 3 (show CASP3 ELISA Kits) and caspase 8), cAMP activation of PKA but not of Epac (show RAPGEF3 ELISA Kits), and on activation of MLCK (show MYLK ELISA Kits).

  7. Internalized Cryptococcus neoformans Activates the Canonical Caspase-1 (show CASP1 ELISA Kits) and the Noncanonical Caspase-8 Inflammasomes.

  8. Casp8-dependent migration of enterocytes is likely involved in intestinal physiology and inflammation-related pathophysiology.

  9. NLRP3 (show NLRP3 ELISA Kits) inflammasomes directly utilize caspase-8 as both a pro-apoptotic initiator and major IL-1beta (show IL1B ELISA Kits)-converting protease

  10. The non-receptor tyrosine kinase (show TNK1 ELISA Kits) Tec (show NR4A3 ELISA Kits) controls assembly and activity of the noncanonical caspase-8 inflammasome.

Human Caspase 8, Apoptosis-Related Cysteine Peptidase (CASP8) interaction partners

  1. Frequencies of SNPs rs2234978 and rs1045487 of FAS (show FAS ELISA Kits) and CASP8 genes were significantly higher in Autoimmune Lymphoproliferative Syndrome patients.

  2. procaspase-8:c-FLIPL (show CFLAR ELISA Kits) exhibits localized enzymatic activity and is preferentially an activator, promoting DED (show AATF ELISA Kits)-mediated procaspase-8 oligomer assembly, whereas procaspase-8:c-FLIPS (show CFLAR ELISA Kits) lacks activity and potently blocks procaspase-8 activation

  3. A20 targets caspase-8 and FADD to protect HTLV-I-infected cells.

  4. HER2 (show ERBB2 ELISA Kits) promotes tumor cell survival by inhibiting apoptosis i.e. by downregulating CASP-3 (show CASP3 ELISA Kits) and CASP-8.

  5. Studied the mechanism of Artemisinin (ARTE)-induced human lung adenocarcinoma (ASTC-a-1) cell apoptosis; results showed ARTE induced the activation of caspase-3 (show CASP3 ELISA Kits), -8 and -9.

  6. ASC (show PYCARD ELISA Kits) induces procaspase-8 death effector domain filaments

  7. A frame-shift and a novel missense mutation in CASP8 gene is associated with oral Squamous Cell Carcinoma.

  8. in the absence of caspase-8 activity, 24(S)-Hydroxycholesterol induces a necroptosis-like cell death which is RIPK1-dependent but MLKL-independent.

  9. a novel small molecule that not only stimulates TRAIL-induced apoptosis in cancer cells, but may also provide insights into the structure-function relationship of caspase 8 homodimers as putative targets in cancer.

  10. The phylogenetic distribution of caspase-8, the initiator caspase (show CASP3 ELISA Kits) of the extrinsic apoptotic pathway. [Review]

Cow (Bovine) Caspase 8, Apoptosis-Related Cysteine Peptidase (CASP8) interaction partners

  1. S. aureus-induced apoptosis in bovine mammary epithelial cells apoptosis was mitigated by caspase-3 (show CASP3 ELISA Kits) and caspase-8 inhibitors, suggesting that apoptosis is initiated via caspase-8 activation.

  2. Endothelial cell apoptosis by H. somnus-activated platelets required activation of both caspase-8 and caspase-9 (show CASP9 ELISA Kits).

Pig (Porcine) Caspase 8, Apoptosis-Related Cysteine Peptidase (CASP8) interaction partners

  1. Nitric oxide-dependent increase in caspase-8 mRNA levels is associated with phosphorylation of STAT-1 (show STAT1 ELISA Kits) at Ser (show SIGLEC1 ELISA Kits)-727 and STAT1 (show STAT1 ELISA Kits) binding to the caspase-8 promoter in cultured lung endothelial cells.

  2. Data show that cysteine significantly reduced the expression of pro-inflammatory cytokines, including TNF-alpha (show TNF ELISA Kits), IL-6 (show IL6 ELISA Kits), IL-12p40, IL-1beta (show IL1B ELISA Kits), and resulted in increased expression of the apoptosis initiator caspase-8 and bcl2L1 (show BCL2L1 ELISA Kits).

Zebrafish Caspase 8, Apoptosis-Related Cysteine Peptidase (CASP8) interaction partners

  1. Targeted gene knockdown of TNFRSF1B (show TNFRSF1B ELISA Kits) in zebrafish embryos results in the induction of a caspase-8, caspase-2 (show CASP2 ELISA Kits) and P53 (show TP53 ELISA Kits)-dependent apoptotic program in endothelial cells that bypasses caspase-3 (show CASP3 ELISA Kits).

  2. These results show that zebrafish casp8 has a structure and function similar to mammalian CASP8 orthologs and the role of caspase-8 in the apoptotic signal pathway has been conserved over at least 450 million years of vertebrate evolution.

Caspase 8 (CASP8) Antigen Profile

Antigen Summary

This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain, a large protease subunit, and a small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This protein is involved in the programmed cell death induced by Fas and various apoptotic stimuli. The N-terminal FADD-like death effector domain of this protein suggests that it may interact with Fas-interacting protein FADD. This protein was detected in the insoluble fraction of the affected brain region from Huntington disease patients but not in those from normal controls, which implicated the role in neurodegenerative diseases. Many alternatively spliced transcript variants encoding different isoforms have been described, although not all variants have had their full-length sequences determined.

Alternative names and synonyms associated with Caspase 8 (CASP8)

  • caspase 8, apoptosis-related cysteine peptidase (casp8) Elisa Kit
  • death related ced-3/Nedd2-like protein (Dredd) Elisa Kit
  • caspase 8, apoptosis-related cysteine peptidase (CASP8) Elisa Kit
  • caspase-8 (AaeL_AAEL014148) Elisa Kit
  • caspase-8 (casp8) Elisa Kit
  • caspase 8 (LOC100222284) Elisa Kit
  • caspase 8 (Casp8) Elisa Kit
  • caspase 8 (LOC100348477) Elisa Kit
  • ALPS2B Elisa Kit
  • CAP4 Elisa Kit
  • Casp-8 Elisa Kit
  • CASP8 Elisa Kit
  • casp8-A Elisa Kit
  • caspase-8 Elisa Kit
  • FLICE Elisa Kit
  • MACH Elisa Kit
  • MCH5 Elisa Kit
  • xCaspase-8 Elisa Kit
  • zgc:92075 Elisa Kit

Protein level used designations for CASP8

caspase-8 , xcaspase 8 , death related ced-3/Nedd2-like protein , GLEAN_14026 , caspase 8, apoptosis-related cysteine peptidase , caspase 8 , caspase-8-like , DEATH effector domain caspase , Fas-linked ICE-like protease , FADD-homologous ICE/CED-3-like protease , FADD-like ICE , ICE-like apoptotic protease 5 , MACH-alpha-1/2/3 protein , MACH-beta-1/2/3/4 protein , MORT1-associated ced-3 homolog , apoptotic cysteine protease , apoptotic protease Mch-5 , caspase 8, apoptosis-related cysteine protease , caspase-8a , cysteine protease

373559 Xenopus laevis
661095 Tribolium castaneum
702781 Macaca mulatta
5563818 Aedes aegypti
100049400 Oryzias latipes
100066502 Equus caballus
100142684 Felis catus
100172115 Pongo abelii
100222284 Taeniopygia guttata
100472842 Ailuropoda melanoleuca
100579132 Hydra magnipapillata
100586183 Nomascus leucogenys
12370 Mus musculus
64044 Rattus norvegicus
100348477 Oryctolagus cuniculus
841 Homo sapiens
746477 Pan troglodytes
507481 Bos taurus
395284 Gallus gallus
488473 Canis lupus familiaris
595105 Sus scrofa
101107334 Ovis aries
58022 Danio rerio
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