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anti-Mouse (Murine) DFFB antibody for Immunocytochemistry

Recommended DFFB Antibody (supplied by: Log in to see )

Antigen
DNA Fragmentation Factor, 40kDa, beta Polypeptide (Caspase-Activated DNase) (DFFB) Antibodies
  • 40kDa
  • 5730477D02Rik
  • CAD
  • Cad
  • CPAN
  • DFF-40
  • DFF2
  • DFF40
  • Didff
  • LOC100223514
Reactivity
Human, Mouse (Murine), Rat (Rattus)
126
71
51
1
Host
Rabbit
131
29
Clonality
Polyclonal
Conjugate
This DFFB antibody is un-conjugated
6
5
5
3
3
3
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunocytochemistry (ICC), ELISA, Western Blotting (WB)
131
41
25
22
21
21
17
8
5
3
3
1
Supplier
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Catalog No. ABIN2156250
$ 535.71
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.6663565 ABIN2156249 ICC WB Rabbit AA 203-218 Log in to see Polyclonal
0.0009962841 ABIN1733625 ICC IHC (p) WB Rabbit IgG Internal Region Log in to see Polyclonal
0.0009962841 ABIN1030918 ICC ELISA WB Rabbit Middle Region Log in to see Polyclonal
0.0009962841 ABIN1030919 ICC ELISA WB Rabbit Middle Region Log in to see Polyclonal
0.0009962841 ABIN1886855 ICC ELISA WB Rabbit AA 203-218 Log in to see Polyclonal
0.0009962841 ABIN1887769 ICC ELISA WB Rabbit Center Log in to see Polyclonal
0.0009962841 ABIN1584351 ICC ELISA WB Rabbit Log in to see Polyclonal
0.0009962841 ABIN1584350 ICC ELISA WB Rabbit Log in to see Polyclonal
0.0009962841 ABIN4305068 ELISA ICC IF WB Rabbit Log in to see Polyclonal
0.0009962841 ABIN4305065 ELISA ICC IF WB Rabbit Log in to see Polyclonal
0.0009962841 ABIN4305067 ELISA ICC IF WB Rabbit Log in to see Polyclonal

Similar anti-DFFB Antibodies

Application / Reactivity Rat (Rattus) Mouse (Murine) Human
ELISA 11 Antibodies 13 Antibodies 39 Antibodies
Enzyme Immunoassay (EIA) 3 Antibodies 4 Antibodies
Immunocytochemistry (ICC) 12 Antibodies 12 Antibodies
Immunofluorescence (IF) 6 Antibodies 6 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 22 Antibodies 22 Antibodies
Immunohistochemistry (IHC) 1 Antibodies 7 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 9 Antibodies 12 Antibodies
Western Blotting (WB) 31 Antibodies 51 Antibodies
Dot Blot (DB) 3 Antibodies

General

Antigen DNA Fragmentation Factor, 40kDa, beta Polypeptide (Caspase-Activated DNase) (DFFB) Antibodies
Reactivity Human, Mouse (Murine), Rat (Rattus)
(126), (71), (51), (1)
Host Rabbit
(131), (29)
Clonality
Polyclonal
Conjugate This DFFB antibody is un-conjugated
(6), (5), (5), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunocytochemistry (ICC), ELISA, Western Blotting (WB)
(131), (41), (25), (22), (21), (21), (17), (8), (5), (3), (3), (1)
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Product Details anti-DFFB Antibody

Target Details DFFB Application Details Handling Images
Predicted Reactivity Human Mouse Rat
Characteristics Apoptosis Is Related To Many Diseases And Induced By A Family Of Cell Death Receptors And Their Ligands. Cell Death Signals Are Transduced By Death Domain Containing Adapter Molecules And Members Of The Caspase Family Of Proteases. These Death Signals Finally Cause The Degradation Of Chromosomal Dna By Activated Dnase. A Mouse Dnase That Causes Dna Fragmentation Was Identified Recently And Designated Cad (for Caspase Activated Deoxyribonuclease). The Human Homologue Of Mouse Cad Was More Recently Identified By Three Groups Independently And Termed Cpan, Dff40, And Human Cad, Respectively. Dff45/Icad Is The Inhibitory Protein Of Dff40/Cad And Forms Complex With Dff40/Cad. Upon Cleavage Of Dff45/Icad By Activated Caspase, Dff40/Cad Is Released And Activated And Eventually Causes The Degradation Of Dna In The Nuclei. Activation Of Dff40/Cad, Which Causes Dna Degradation, Is The Hallmark Of Apoptotic Cell Death.
Purification Affinity chromatography purified via peptide column
Immunogen The immunogen for anti-DFF40 antibody: antibody was raised against a peptide corresponding to amino acids near the center of murine CAD. The sequence differs from human DFF40 by two amino acids (3,4).

Target Details DFFB

Product Details anti-DFFB Antibody Application Details Handling Images back to top
Antigen
Alternative Name DFF40 (DFFB Antibody Abstract)
Background Caspase Activated Dnase
Gene ID 1677
NCBI Accession NP_031885
Research Area Apoptosis/Necrosis, DNA/RNA
Pathways Apoptosis, Caspase Cascade in Apoptosis

Application Details

Product Details anti-DFFB Antibody Target Details DFFB Handling Images back to top
Application Notes DFF40 antibody can be used for detection of DFF40 by Western blot at 1:500 to 1:1000 dilution. A 40 kDa band can be detected
Restrictions For Research Use only

Handling

Product Details anti-DFFB Antibody Target Details DFFB Application Details Images back to top
Handling Advice As with all antibodies care should be taken to avoid repeated freeze thaw cycles.
Antibodies should not be exposed to prolonged high temperatures.
Storage 4 °C
Storage Comment DFF40 antibody can be stored at 4 °C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Expiry Date 12 months

Images

Product Details anti-DFFB Antibody Target Details DFFB Application Details Handling back to top
Supplier Images
Western Blotting (WB) image for anti-DFFB antibody (DNA Fragmentation Factor, 40kDa, beta Polypeptide (Caspase-Activated DNase)) (ABIN2156250) anti-DNA Fragmentation Factor, 40kDa, beta Polypeptide (Caspase-Activated DNase) (DFFB) antibody
Immunocytochemistry (ICC) image for anti-DFFB antibody (DNA Fragmentation Factor, 40kDa, beta Polypeptide (Caspase-Activated DNase)) (ABIN2156250) anti-DNA Fragmentation Factor, 40kDa, beta Polypeptide (Caspase-Activated DNase) (DFFB) antibody (Image 2)