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anti-Cow (Bovine) KRT18 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended KRT18 Antibody (supplied by: Log in to see )

Antigen
Keratin 18 (KRT18) Antibodies
  • cb83
  • CK18
  • CYK18
  • dapk1
  • DreK18
  • K18
  • Krt1-18
  • krt18
  • KRT18
  • krtt1c6
  • MGC64569
  • MGC75922
  • sb:cb83
  • wu:fa13f02
  • wu:fb36b04
  • zgc:66015
Reactivity
Cow (Bovine), Dog (Canine), Hamster, Human, Mouse (Murine), Pig (Porcine), Rat (Rattus), Sheep (Ovine), Trout
582
110
97
29
18
17
16
13
10
8
8
6
5
5
3
3
3
3
3
3
3
1
1
1
Host
Mouse
358
258
10
9
6
2
Clonality
Monoclonal
Conjugate
This KRT18 antibody is conjugated to Biotin
39
38
10
4
4
4
3
3
3
3
3
3
3
2
2
1
1
1
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
424
245
200
173
150
121
96
91
62
34
18
11
11
3
2
2
1
1
1
Supplier
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Catalog No. ABIN111181
$ 445.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.00089715846 ABIN111183 IHC (fro) IHC (p) WB Mouse IgG1 Log in to see Ks18-04 12
0.00089715846 ABIN111182 FACS IHC (fro) IF IHC (p) FITC Mouse IgG1 Log in to see Ks18-04 9
0.00089715846 ABIN126072 IHC (fro) IHC (p) WB Guinea Pig Log in to see Polyclonal 1
0.00089715846 ABIN288568 IHC (fro) IHC (p) ELISA WB Biotin Mouse IgG1 Log in to see Ks18-04
0.00089715846 ABIN302712 IHC (p) WB Rabbit Log in to see Polyclonal
0.00089715846 ABIN452377 IHC (fro) IHC (p) WB Mouse IgG1 multi Epitope Log in to see Ks18-04-18-27-18-5-9B1-18-174
0.00089715846 ABIN1736285 IHC (p) WB Rabbit IgG Log in to see Polyclonal
0.00089715846 ABIN3026966 FACS IF IHC (p) Mouse IgG1, kappa Log in to see C-04 or Ks18-04
0.00089715846 ABIN3026968 FACS IF IHC (p) Mouse IgG1, kappa Log in to see C-04 or Ks18-04

Top referenced anti-KRT18 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Similar anti-KRT18 Antibodies

Application / Reactivity Human Cow (Bovine) Dog (Canine) Hamster Mouse (Murine) Pig (Porcine) Rat (Rattus) Sheep (Ovine) Trout
Western Blotting (WB) 392 Antibodies 13 Antibodies 19 Antibodies 7 Antibodies 79 Antibodies 12 Antibodies 64 Antibodies 4 Antibodies 3 Antibodies
Light Microscopy (LM) 3 Antibodies
Immunoprecipitation (IP) 55 Antibodies 2 Antibodies 5 Antibodies 8 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 193 Antibodies 10 Antibodies

General

Antigen Keratin 18 (KRT18) Antibodies
Reactivity Cow (Bovine), Dog (Canine), Hamster, Human, Mouse (Murine), Pig (Porcine), Rat (Rattus), Sheep (Ovine), Trout
(582), (110), (97), (29), (18), (17), (16), (13), (10), (8), (8), (6), (5), (5), (3), (3), (3), (3), (3), (3), (3), (1), (1), (1)
Host Mouse
(358), (258), (10), (9), (6), (2)
Clonality (Clone)
Monoclonal   ( )
Conjugate This KRT18 antibody is conjugated to Biotin
(39), (38), (10), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (2), (2), (1), (1), (1)
Application Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(424), (245), (200), (173), (150), (121), (96), (91), (62), (34), (18), (11), (11), (3), (2), (2), (1), (1), (1)
Pubmed 9 references available
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Product Details anti-KRT18 Antibody

Target Details KRT18 Application Details Handling References for anti-KRT18 Antibody (ABIN111181) Images
Specificity This Monoclonal antibody Ks 18.04 represents an excellent marker to discriminate simple epithelia from those of different origin. Tumors Specifically Detected: all adenocarcinoma, mammary carcinoma, urinary bladder carcinoma, undifferentiated carcinoma, cervix carcinoma, hepatocellular carcinoma. Polypeptide Reacting: Mr 45 000 polypeptide (Human keratin K18, formerly also designated cytokeratin 18) of all simple type epithelia and basal cells of many squamous, nonepidermal epithelia. Tested Reactivities on Cultured Cell Lines: HeLa and MCF-7.
Purification Affinity Chromatography on Protein A
Immunogen Cytokeratin 18 of molecular weight 45kDa. Purified from a HeLa cytoskeletal preparation.
Clone Ks18-04
Isotype IgG1

Target Details KRT18

Product Details anti-KRT18 Antibody Application Details Handling References for anti-KRT18 Antibody (ABIN111181) Images back to top
Antigen
Alternative Name Cytokeratin 18 (KRT18 Antibody Abstract)
Background Cytokeratin 18 is an acidic keratin which is found primarily in non squamous epithelia and is present in a majority of adenocarcinomas and ductal carcinomas but not in squamous cell carcinomas. Cytokeratin 18 exists in combination with Cytokeratin 8, a basic keratin. Hepatocellular carcinomas have been reportedly defined by the use of antibodies that recognize only Cytokeratins 8 and 18.Synonyms: CK18, CYK18, Cell proliferation-inducing gene 46 protein, Cytokeratin-18, K18, KRT18, Keratin 18, Keratin type I cytoskeletal 18, Keratin-18
Gene ID 3875
NCBI Accession NP_000215
UniProt P05783
Research Area Signaling, Cytoskeleton, Extracellular Matrix
Pathways Apoptosis, Caspase Cascade in Apoptosis

Application Details

Product Details anti-KRT18 Antibody Target Details KRT18 Handling References for anti-KRT18 Antibody (ABIN111181) Images back to top
Application Notes Immunohistochemistry on frozen and paraffin sections. ELISA. Immunoblotting.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-KRT18 Antibody Target Details KRT18 Application Details References for anti-KRT18 Antibody (ABIN111181) Images back to top
Format Liquid
Buffer 0.09 % Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

References for anti-KRT18 Antibody (ABIN111181)

Product Details anti-KRT18 Antibody Target Details KRT18 Application Details Handling Images back to top
Product cited in:

Trowe, Airik, Weiss, Farin, Foik, Bettenhausen, Schuster-Gossler, Taketo, Kispert: "Canonical Wnt signaling regulates smooth muscle precursor development in the mouse ureter." in: Development (Cambridge, England), Vol. 139, Issue 17, pp. 3099-108, 2012

Hantel, Lewrick, Schneider, Zwermann, Perren, Reincke, Süss, Beuschlein: "Anti insulin-like growth factor I receptor immunoliposomes: a single formulation combining two anticancer treatments with enhanced therapeutic efficiency." in: The Journal of clinical endocrinology and metabolism, Vol. 95, Issue 2, pp. 943-52, 2010

Stumptner, Fuchsbichler, Heid, Zatloukal, Denk: "Mallory body--a disease-associated type of sequestosome." in: Hepatology (Baltimore, Md.), Vol. 35, Issue 5, pp. 1053-62, 2002

Bantel, Ruck, Gregor, Schulze-Osthoff: "Detection of elevated caspase activation and early apoptosis in liver diseases." in: European journal of cell biology, Vol. 80, Issue 3, pp. 230-9, 2001

Gomi, Yokoyama, Fujimoto, Ikeda, Katoh, Itoh, Itohara: "Mice devoid of the glial fibrillary acidic protein develop normally and are susceptible to scrapie prions." in: Neuron, Vol. 14, Issue 1, pp. 29-41, 1995

Bártek, Vojt?sek, Stasková, Bártková, Kerekés, Rejthar, Kovarík: "A series of 14 new monoclonal antibodies to keratins: characterization and value in diagnostic histopathology." in: The Journal of pathology, Vol. 164, Issue 3, pp. 215-24, 1991

Lauerová, Kovarik, Bártek, Rejthar, Vojt?sek: "Novel monoclonal antibodies defining epitope of human cytokeratin 18 molecule." in: Hybridoma, Vol. 7, Issue 5, pp. 495-504, 1989

Background publications

Ikenouchi, Matsuda, Furuse, Tsukita: "Regulation of tight junctions during the epithelium-mesenchyme transition: direct repression of the gene expression of claudins/occludin by Snail." in: Journal of cell science, Vol. 116, Issue Pt 10, pp. 1959-67, 2003

Moll, Franke, Schiller, Geiger, Krepler: "The catalog of human cytokeratins: patterns of expression in normal epithelia, tumors and cultured cells." in: Cell, Vol. 31, Issue 1, pp. 11-24, 1983