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anti-Human KRT18 antibody for Biochemical Assay

Recommended KRT18 Antibody (supplied by: Log in to see )

Antigen
Keratin 18 (KRT18) Antibodies
  • cb83
  • CK18
  • CYK18
  • dapk1
  • DreK18
  • K18
  • Krt1-18
  • krt18
  • KRT18
  • krtt1c6
  • MGC64569
  • MGC75922
  • sb:cb83
  • wu:fa13f02
  • wu:fb36b04
  • zgc:66015
Reactivity
Human
900
168
143
57
55
34
29
25
20
19
19
18
13
12
7
7
7
5
4
3
3
3
1
1
1
Host
Mouse
666
268
10
9
6
2
Clonality
Monoclonal
Conjugate
This KRT18 antibody is un-conjugated
51
47
21
18
18
17
14
14
14
14
14
14
14
14
14
14
11
11
4
3
3
3
3
3
3
2
2
1
1
1
Application
Biochemical Assay (BCA)
627
448
379
340
312
273
252
194
165
34
18
12
11
9
3
2
1
1
1
1
Supplier
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Catalog No. ABIN2664917
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Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.00088717224 ABIN2664918 BCA Mouse IgG1 kappa Log in to see DA-7 5

Top referenced anti-KRT18 antibody for Biochemical Assay

Similar anti-KRT18 Antibodies

Application / Reactivity Human
Biochemical Assay (BCA) 2 Antibodies
ELISA 249 Antibodies
Enzyme Immunoassay (EIA) 10 Antibodies
FLISA 1 Antibodies
Flow Cytometry (FACS) 369 Antibodies
Immunochromatography (IC) 18 Antibodies
Immunocytochemistry (ICC) 240 Antibodies
Immunofluorescence (IF) 338 Antibodies
Immunofluorescence (Cultured Cells) (IF (cc)) 11 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 23 Antibodies
Immunohistochemistry (IHC) 301 Antibodies
Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) 2 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 190 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 438 Antibodies
Immunoprecipitation (IP) 156 Antibodies

General

Antigen Keratin 18 (KRT18) Antibodies
Reactivity Human
(900), (168), (143), (57), (55), (34), (29), (25), (20), (19), (19), (18), (13), (12), (7), (7), (7), (5), (4), (3), (3), (3), (1), (1), (1)
Host Mouse
(666), (268), (10), (9), (6), (2)
Clonality (Clone)
Monoclonal   ( )
Conjugate This KRT18 antibody is un-conjugated
(51), (47), (21), (18), (18), (17), (14), (14), (14), (14), (14), (14), (14), (14), (14), (14), (11), (11), (4), (3), (3), (3), (3), (3), (3), (2), (2), (1), (1), (1)
Application Biochemical Assay (BCA)
(627), (448), (379), (340), (312), (273), (252), (194), (165), (34), (18), (12), (11), (9), (3), (2), (1), (1), (1), (1)
Pubmed 5 references available
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Product Details anti-KRT18 Antibody

Target Details KRT18 Application Details Handling References for anti-KRT18 Antibody (ABIN2664917) Images
Purification The antibody was purified by affinity chromatography.
Clone DA-7
Isotype IgG1 kappa

Target Details KRT18

Product Details anti-KRT18 Antibody Application Details Handling References for anti-KRT18 Antibody (ABIN2664917) Images back to top
Antigen
Alternative Name Cytokeratin 18 (KRT18 Antibody Abstract)
Background Cytokeratin 18, also known as keratin 18, is a type I intermediate filament protein with a molecular weight of approximately 48 kD. Cytokeratin 18 is a heterotetramer composed of two type I and two type II keratins. Cytokeratin 18 associates with cytokeratin 8 and is widely expressed in simple epithelial tissues in adults, where it is found in the cytoplasm, nucleus, and nucleolus. Cytokeratin 18 is associated with the cytoskeleton and mutations in this protein have been associated with liver disease after environmental insult. Cytokeratin 18 can be modified by glycosylation, phosphorylation (Ser34 and Ser53), acetylation (Ser2), and proteolytic cleavage at amino acids 238 and 397 by caspase family members. The cytokeratin 18 protein interacts with a number of proteins including caspase 3, 14-3-3 gamma, 14-3-3 zeta, 14-3-3 sigma 14-3-3 beta, 14-3-3 eta, keratin 5, keratin 8, TNF receptor II, plakophilin 2, EGF receptor, and usherin, among others.
Research Area Signaling, Cytoskeleton, Extracellular Matrix
Pathways Apoptosis, Caspase Cascade in Apoptosis

Application Details

Product Details anti-KRT18 Antibody Target Details KRT18 Handling References for anti-KRT18 Antibody (ABIN2664917) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-KRT18 Antibody Target Details KRT18 Application Details References for anti-KRT18 Antibody (ABIN2664917) Images back to top
Concentration 0.5 mg/mL
Buffer phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide at 0.5 mg/mL.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment The antibody solution should be stored undiluted between 2°C and 8°C.

References for anti-KRT18 Antibody (ABIN2664917)

Product Details anti-KRT18 Antibody Target Details KRT18 Application Details Handling Images back to top
Background publications

Ku, Darling, Krams, Esquivel, Keeffe, Sibley, Lee, Wright, Omary: "Keratin 8 and 18 mutations are risk factors for developing liver disease of multiple etiologies." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 100, Issue 10, pp. 6063-8, 2003

Taylor-Papadimitriou, Stampfer, Bartek, Lewis, Boshell, Lane, Leigh: "Keratin expression in human mammary epithelial cells cultured from normal and malignant tissue: relation to in vivo phenotypes and influence of medium." in: Journal of cell science, Vol. 94 ( Pt 3), pp. 403-13, 1990

Kulesh, Oshima: "Complete structure of the gene for human keratin 18." in: Genomics, Vol. 4, Issue 3, pp. 339-47, 1989

Lauerová, Kovarik, Bártek, Rejthar, Vojt?sek: "Novel monoclonal antibodies defining epitope of human cytokeratin 18 molecule." in: Hybridoma, Vol. 7, Issue 5, pp. 495-504, 1989

Steinert, Roop: "Molecular and cellular biology of intermediate filaments." in: Annual review of biochemistry, Vol. 57, pp. 593-625, 1988

Images

Product Details anti-KRT18 Antibody Target Details KRT18 Application Details Handling References for anti-KRT18 Antibody (ABIN2664917) back to top
Supplier Images
Immunofluorescence (IF) image for anti-KRT18 antibody (Keratin 18) (ABIN2664917) anti-Keratin 18 (KRT18) antibody
Immunofluorescence (IF) image for anti-KRT18 antibody (Keratin 18) (ABIN2664917) anti-Keratin 18 (KRT18) antibody (Image 2)
Western Blotting (WB) image for anti-KRT18 antibody (Keratin 18) (ABIN2664917) anti-Keratin 18 (KRT18) antibody (Image 3)