anti-Human TNFRSF10C antibody for Functional Studies

Recommended TNFRSF10C Antibody (supplied by: Log in to see )

Antigen
Tumor Necrosis Factor Receptor Superfamily, Member 10c, Decoy Without An Intracellular Domain (TNFRSF10C) Antibodies
  • CD263
  • DCR1
  • DCR1-TNFR
  • LIT
  • TRAIL-R3
  • TRAILR3
  • TRID
  • TNFRSF10C
  • tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain
  • TNFRSF10C
Reactivity
Human
153
18
15
7
Host
Mouse
110
47
3
3
Clonality
Monoclonal
Conjugate
This TNFRSF10C antibody is un-conjugated
19
14
5
5
4
4
3
3
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
Application
Functional Studies (Func)
92
75
31
23
17
12
7
6
2
2
2
1
1
1
Supplier
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Catalog No. ABIN1106169
$ 308.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN1722627 Func Mouse IgG1 Log in to see B-D44

General

Antigen Tumor Necrosis Factor Receptor Superfamily, Member 10c, Decoy Without An Intracellular Domain (TNFRSF10C) Antibodies
Reactivity Human
(153), (18), (15), (7)
Host Mouse
(110), (47), (3), (3)
Clonality (Clone)
Monoclonal   ( )
Conjugate This TNFRSF10C antibody is un-conjugated
(19), (14), (5), (5), (4), (4), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1)
Application Functional Studies (Func)
(92), (75), (31), (23), (17), (12), (7), (6), (2), (2), (2), (1), (1), (1)
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Product Details anti-TNFRSF10C Antibody

Target Details TNFRSF10C Application Details Handling Images
Specificity Recognizes the soluble antigen. Recognizes the 75-90 kDa protein.
Cross-Reactivity (Details) Species reactivity (tested):Human.
Purification Ion Exchange Chromatography.
Sterility 0.22 μm filtered
Immunogen Recombinant Human TRAIL R3/Fc chimera. Hybridoma: Myeloma X63/AG.8653 x Balb/c spleen cells.
Clone B-D44
Isotype IgG1

Target Details TNFRSF10C

Product Details anti-TNFRSF10C Antibody Application Details Handling Images back to top
Antigen
Alternative Name CD263 / TRAILR3 (TNFRSF10C Antibody Abstract)
Background TRAIL-R3 (CD263, TR3, DcR1, LIT, TRID), expressed mainly on neutrophils, belongs to receptors of TRAIL, a TNF-like membrane cytotoxic protein that induces apoptosis in many tumour cells, but not in normal cells. TRAIL-R3, however, is a GPI-anchored protein that lacks cytoplasmic death domain, thus it is unable to induce apoptosis and serves as a negative regulator of apoptotic signaling by competing for binding of TRAIL with death receptor 5 (DR5).Synonyms: Antagonist decoy receptor for TRAIL/Apo-2L, DCR1, Decoy TRAIL receptor without death domain, Decoy receptor 1, LIT, Lymphocyte inhibitor of TRAIL, TNF-related apoptosis-inducing ligand receptor 3, TNFRSF10C, TRAIL receptor 3, TRAIL-R3, TRID, Trail receptor without an intracellular domain, Tumor necrosis factor receptor superfamily member 10C
Gene ID 8794
NCBI Accession NP_003832
UniProt O14798
Research Area Signaling, Apoptosis/Necrosis
Pathways Apoptosis

Application Details

Product Details anti-TNFRSF10C Antibody Target Details TNFRSF10C Handling Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-TNFRSF10C Antibody Target Details TNFRSF10C Application Details Images back to top
Buffer Phosphate-buffered saline without Carrier and preservatives. This prodcut is sterile-filtered through 0.22 μm and treated to remove Endotoxins.
Preservative Without preservative
Storage 4 °C
Storage Comment Store the antibody undiluted at 2-8 °C.