Browse our Prostacyclin Receptor Proteins (PTGIR)

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Prostacyclin Receptor Proteins (PTGIR)
On www.antibodies-online.com are 5 Prostacyclin Receptor (PTGIR) Proteins from 2 different suppliers available. Additionally we are shipping Prostacyclin Receptor Antibodies (68) and Prostacyclin Receptor Kits (5) and many more products for this protein. A total of 80 Prostacyclin Receptor products are currently listed.
Synonyms:
IP, PGI2, PRIPR
list all proteins Gene Name GeneID UniProt
PTGIR 19222 P43252
PTGIR 5739 P43119
Rat PTGIR PTGIR 292661 P43253

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Prostacyclin Receptor Proteins (PTGIR) by Origin

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More Proteins for Prostacyclin Receptor Interaction Partners

Mouse (Murine) Prostacyclin Receptor (PTGIR) interaction partners

  1. results provide evidence that PGI2/IP signaling suppresses the STAT6 (show STAT6 Proteins)-independent pathway of allergic airway inflammation

  2. Data (including data from studies using transgenic mice, an murine experimental model of diabetes, and mouse/human cell lines) suggest prostaglandin I2 receptor (Ptgir) is involved in insulin (show INS Proteins) secretion in pancreatic beta-cells and in permselectivity in glomerular podocytes; the mechanism appears to involve regulation of post-translational phosphorylation of nephrin (show NPHS1 Proteins).

  3. Deletion of the I prostanoid receptor had no effect on the attenuation of atherogenesis by mPGES-1 (show PTGES Proteins) deletion in the low-density lipoprotein receptor (show LDLR Proteins) knockout mice.

  4. Prostacyclin promotes the up-regulation of Nox4 (show NOX4 Proteins) in endothelial cells, which opens up a novel strategy that protects and enhances endothelial cell functions in cardiovascular disease, such as repair after myocardial infarction or other ischemic conditions.

  5. Its signaling increase cAMP concentration, which prototes sysnesis of HGF (show HGF Proteins), causing angiogenesis.

  6. an essential role of the COX-2/PGI2 receptor axis in the cardioprotection afforded by the late ischemic preconditioning

  7. findings suggest the IP receptor might maintain an angiogenic switch in the "on" state in tumor endothelial cells (TEC); suggest that the IP receptor is a TEC-specific marker and might be a useful therapeutic target

  8. PGI2-induced PPAR delta (show PPARD Proteins) activation accelerates blastocyst hatching in mice

  9. For the first time these results show that activation of prostaglandin I2 receptor can attenuate damage following cerebral ischemia.

  10. identify PGI(2)-prostaglandin I2 receptor as an important pathway for inhibiting allergic pulmonary inflammation by controlling recruitment of CD4 (show CD4 Proteins)(+) Th2 cells into the inflammatory site

Human Prostacyclin Receptor (PTGIR) interaction partners

  1. role of IP-PPARdelta (show PPARD Proteins) signal transduction pathway in the production of sAPPalpha in cerebral microvasculature.

  2. Data (including data from studies using transgenic mice, an murine experimental model of diabetes, and mouse/human cell lines) suggest prostaglandin I2 receptor (PTGIR) is involved in insulin (show INS Proteins) secretion in pancreatic beta-cells and in permselectivity in glomerular podocytes; the mechanism appears to involve regulation of post-translational phosphorylation of nephrin (show NPHS1 Proteins).

  3. The human prostacyclin receptor gene is under the transcriptional regulation of dihydrotestosterone, where this regulation is further influenced by serum-cholesterol levels.

  4. these findings suggest that reduced IPR expression in DM2 (show CNBP Proteins) platelets may contribute to platelet hyperactivity in humans with type 2 diabetes.

  5. Prostaglandin I2- Prostaglandin I2 receptor signaling regulates human Th17 and Treg cell differentiation.

  6. these data provide critical insights into the transcriptional regulation of the human prostacyclin receptor gene within the vasculature, including during megakaryocytic differentiation

  7. IP receptor heteridimerization with thromboxane receptor (show TBXA2R Proteins) facilitates receptor trafficking to membrane lipid rafts.

  8. Prostacyclin receptor-dependent inhibition of human erythroleukemia cell differentiation is STAT3 (show STAT3 Proteins)-dependent

  9. IKEPP (show PDZD3 Proteins) was also found to be expressed in vascular endothelial cells where it co-localizes and complexes with the hIP

  10. the IP receptor was expressed in blood vessels of renal cell carcinoma specimens, but not in glomerular vessels of normal renal tissue; findings suggest the IP receptor might maintain an angiogenic switch in the "on" state in tumor endothelial cells (TEC); suggest that the IP receptor is a TEC-specific marker and might be a useful therapeutic target

Prostacyclin Receptor (PTGIR) Protein Profile

Protein Summary

The protein encoded by this gene is a member of the G-protein coupled receptor family 1 and has been shown to be a receptor for prostacyclin. Prostacyclin, the major product of cyclooxygenase in macrovascular endothelium, elicits a potent vasodilation and inhibition of platelet aggregation through binding to this receptor.

Alternative names and synonyms associated with Prostacyclin Receptor (PTGIR)

  • prostaglandin I receptor (IP) (Ptgir)
  • prostaglandin I2 (prostacyclin) receptor (IP) (PTGIR)
  • prostaglandin I2 (prostacyclin) receptor (IP) (Ptgir)
  • IP protein
  • PGI2 protein
  • PRIPR protein

Protein level used designations for Prostacyclin Receptor Proteins (PTGIR)

PGI receptor , PGI2 receptor , prostacyclin receptor , prostaglandin I2 receptor , prostanoid IP receptor , prostaglandin I receptor (IP)

GENE ID SPECIES
19222 Mus musculus
5739 Homo sapiens
292661 Rattus norvegicus
520278 Bos taurus
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