Browse our anti-RAN Binding Protein 2 (RANBP2) Antibodies

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anti-RAN Binding Protein 2 Antibodies (RANBP2)
On are 47 RAN Binding Protein 2 (RANBP2) Antibodies from 8 different suppliers available. A total of 47 RAN Binding Protein 2 products are currently listed.
A430087B05Rik, AI256741, ANE1, IIAE3, MGC76028, NUP358, RANBP2, RGD1560047, TRP1, TRP2
list all antibodies Gene Name GeneID UniProt
RANBP2 5903 P49792
RANBP2 19386 Q9ERU9
RANBP2 294429  

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Top referenced anti-RAN Binding Protein 2 Antibodies

  1. Human Polyclonal RANBP2 Primary Antibody for ICC, IF - ABIN3201003 : Yokoyama, Hayashi, Seki, Panté, Ohba, Nishii, Kuma, Hayashida, Miyata, Aebi: A giant nucleopore protein that binds Ran/TC4. in Nature 1995 (PubMed)

  2. Cow (Bovine) Polyclonal RANBP2 Primary Antibody for IHC (p), IHC - ABIN266970 : Hamard, Boyer-Guittaut, Camuzeaux, Dujardin, Hauss, Oelgeschläger, Vigneron, Kedinger, Chatton: Sumoylation delays the ATF7 transcription factor subcellular localization and inhibits its transcriptional activity. in Nucleic acids research 2007 (PubMed)

More Antibodies against RAN Binding Protein 2 Interaction Partners

Human RAN Binding Protein 2 (RANBP2) interaction partners

  1. Nup358-AGO interaction is important for miRNA-mediated gene silencing and identifies SIM (show SIM2 Antibodies) as a new interacting motif for the AGO family of proteins.

  2. recurrent or familial ANE without the RANBP2 mutation has a more severe outcome and greater predilection for male sex than that with the RANBP2 mutation. This suggests that there are unknown gene mutations linked to ANE.

  3. Based on the literature review of ANE1 with RANBP2 mutation, we propose a threshold for RANBP2 mutation tes (show TES Antibodies)

  4. findings indicate that RanGDP and not RanGTP is the physiological target for the RanBP2 SUMO E3 ligase (show PIAS1 Antibodies) complex

  5. Taken together, topographic and functional interactions between dynactin (show DCTN1 Antibodies), importin-beta (show KPNB1 Antibodies) and RanBP2 are involved in nuclear translocation of IGF-1R (show IGF1R Antibodies).

  6. analysis of the RANBP2-ALK (show ALK Antibodies) gene fusion identified in ALK (show ALK Antibodies)-positive diffuse large B-cell lymphoma with a unique nuclear membrane staining of ALK (show ALK Antibodies) protein

  7. Nup358, a nucleoporin that forms the cytoplasmic filaments of the nuclear pore complex, plays an important role in the nuclear import of hTERT.

  8. Our data show that Nup358 supports nuclear transport functions important for cellular homeostasis and for HIV-1 nuclear import

  9. Case Report/Review: RANBP2-ALK (show ALK Antibodies) gene rearrangement in inflammatory myofibroblastic tumors.

  10. RANBP2-ALK (show ALK Antibodies) fusion combined with monosomy 7 may be related to a unique clonal hematologic disorder of childhood and adolescence, characterized by myelomonocytic leukemia and a poor prognosis [case report/ review]

Cow (Bovine) RAN Binding Protein 2 (RANBP2) interaction partners

  1. reports identification of the cyclophilin-related protein (show PPID Antibodies), RanBP2 (note at the time the protein was not designated RanBP2), and the cis (show CISH Antibodies)-trans prolyl isomerase activity of its cyclophilin (show PPIE Antibodies) domain

  2. reports interaction of the RBD4 and CY domains of RanBP2 with red/green opsin (show OPN1MW Antibodies) and the chaperone activity of these domains toward red/green opsin (show OPN1MW Antibodies).

  3. reports interaction of the RBD4 and CY domains of RanBP2 with red/green opsin (show OPN1MW Antibodies) and the chaperone activity of these domains toward red/green opsin (show OPN1MW Antibodies).

  4. reports identification of a binding domain in RanBP2, the cyclophilin (show PPIE Antibodies)-like domain, toward components of the 19S cap of the proteasome

  5. reports identification of a binding domain in RanBP2, the zinc-finger rich domain, toward CRM1/exportin-1 (show XPO1 Antibodies)

  6. reports identification of a novel domain in RanBP2 located between RBD2 and RBD3 with specific binding activity against the conventional heavy chain kinesins, KIF5B (show KIF5B Antibodies) and KIF5C (show KIF5C Antibodies)

  7. reports the novel subcellular localizations of RanBP2 in retinal neurons of human and bovine

  8. the cyclophilin-like domain of Ran-binding protein-2 modulates selectively the activity of the ubiquitin-proteasome system and protein biogenesis

Mouse (Murine) RAN Binding Protein 2 (RANBP2) interaction partners

  1. Data (including data from studies in transgenic/knockout mice) suggest that Ranbp2 in photoreceptor neurons participates in coupling of photoreceptor degeneration (neural dysmorphology) and apoptosis (neural death) caused by toxic exposure to light.

  2. These studies unravel selective roles of Ranbp2 and its RBD2 and RBD3 in retinal pigment epithelium survival and functions.

  3. These results unveil distinct mechanistic and biological links between prolyl isomerase and chaperone activities of Ranbp2 cyclophilin (show PPIE Antibodies) toward proteostasis.

  4. Novel roles in Ran GTPase (show RAN Antibodies)-independent subdomains of RBD2 and RBD3, and KBD of RanBP2, confer antagonizing and multi-modal mechanisms of kinesin-1 activation and regulation of mitochondrial motility.

  5. Ranbp2 haploinsufficiency is associated with metabolic imbalances leading to parkinson's disease.

  6. Knockdown of RANBP2 specifically affected the late step of nuclear entry, inducing cytoplasmic granules enriched with phosphorylated components. This suggests a novel regulatory mechanism for nuclear speckle formation involving RANBP2 and phosphorylation.

  7. A critical function of RanBP2 is to capture recycling RanGTP-importin-beta (show KPNB1 Antibodies) complexes at cytoplasmic fibrils to allow for adequate classical nuclear localization signal-mediated cargo import.

  8. findings indicate that the nuclear pore complex undergoes dynamic remodeling during muscle cell differentiation and that Nup358 is prominently involved in the remodeling process

  9. These results provide a rationale for the neuroprotection from light damage of photosensory neurons by RANBP2 insufficiency.

  10. RanBP2 associates in vitro and in vivo and colocalizes with the mitochondrial metallochaperone, Cox11 (show COX11 Antibodies), and the pacemaker of glycolysis, hexokinase type I (HKI (show HK1 Antibodies)) via its leucine-rich domain.

RAN Binding Protein 2 (RANBP2) Antigen Profile

Antigen Summary

RAN is a small GTP-binding protein of the RAS superfamily that is associated with the nuclear membrane and is thought to control a variety of cellular functions through its interactions with other proteins. This gene encodes a very large RAN-binding protein that immunolocalizes to the nuclear pore complex. The protein is a giant scaffold and mosaic cyclophilin-related nucleoporin implicated in the Ran-GTPase cycle. The encoded protein directly interacts with the E2 enzyme UBC9 and strongly enhances SUMO1 transfer from UBC9 to the SUMO1 target SP100. These findings place sumoylation at the cytoplasmic filaments of the nuclear pore complex and suggest that, for some substrates, modification and nuclear import are linked events. This gene is partially duplicated in a gene cluster that lies in a hot spot for recombination on chromosome 2q.

Alternative names and synonyms associated with RAN Binding Protein 2 (RANBP2)

  • RAN binding protein 1 (ranbp1) antibody
  • RAN binding protein 2 (RANBP2) antibody
  • RAN binding protein 2 (ranbp2) antibody
  • RAN binding protein 2 (Ranbp2) antibody
  • A430087B05Rik antibody
  • AI256741 antibody
  • ANE1 antibody
  • IIAE3 antibody
  • MGC76028 antibody
  • NUP358 antibody
  • RANBP2 antibody
  • RGD1560047 antibody
  • TRP1 antibody
  • TRP2 antibody

Protein level used designations for RANBP2

RAN binding protein 1 , RAN binding protein 2 , e3 SUMO-protein ligase RanBP2-like , 358 kDa nucleoporin , E3 SUMO-protein ligase RanBP2 , P270 , nuclear pore complex protein Nup358 , nucleoporin 358 , nucleoporin Nup358 , ran-binding protein 2 , transformation-related protein 2 , p270

394616 Xenopus (Silurana) tropicalis
474539 Canis lupus familiaris
100060826 Equus caballus
100134999 Xenopus (Silurana) tropicalis
100511376 Sus scrofa
735654 Pan troglodytes
100020173 Monodelphis domestica
5903 Homo sapiens
785768 Bos taurus
19386 Mus musculus
294429 Rattus norvegicus
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