Browse our anti-Desmoplakin (DSP) Antibodies

On www.antibodies-online.com are 50 Desmoplakin (DSP) Antibodies from 16 different suppliers available. Additionally we are shipping Desmoplakin Kits (23) and and many more products for this protein. A total of 79 Desmoplakin products are currently listed.
Synonyms:
2300002E22Rik, 5730453H04Rik, AA407887, AA407888, AW109828, DP, DPI, DPII, DSP, fi04e12, im:6911953, sb:cb570, wu:fc17a08, wu:fk73d01
list all antibodies Gene Name GeneID UniProt
DSP 100540  
DSP 1832 P15924
DSP 306871  

Most Popular Reactivities for anti-Desmoplakin (DSP) Antibodies

anti-Mouse (Murine) Desmoplakin Antibodies:

anti-Human Desmoplakin Antibodies:

anti-Rat (Rattus) Desmoplakin Antibodies:

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More Antibodies against Desmoplakin Interaction Partners

Mouse (Murine) Desmoplakin (DSP) interaction partners

  1. Conditional heterozygous deletion of Dsp in mice led to increased fibroadipogenesis in the heart and mild cardiac dysfunction.

  2. Our data suggest that endurance exercise accelerates arrhythmogenic ventricular cardiomyopathy pathogenesis in transgenic DSP mice

  3. GSK3 (show GSK3b Antibodies)- and PRMT-1 (show PRMT1 Antibodies)-dependent modifications of desmoplakin control desmoplakin-cytoskeleton dynamics.

  4. These data indicate a function of desmoplakin in motor nerve regeneration by linking N-cadherin (show CDH2 Antibodies) to intermediate filaments in regenerating motor axons.

  5. A loss of desmoplakin expression led to an abnormal distribution of Cx43 (show GJA1 Antibodies) and Nav1.5 (show SCN5A Antibodies), while scrapeloading dye/transfer revealed a decrease in dye transfer in DSP siRNAtreated cells.

  6. the desmosomal protein desmoplakin is not essential for cell adhesion in the intestinal epithelium.

  7. Fxr1 (show FXR1 Antibodies) knockout hearts exhibit an up-regulation of desmoplakin and talin2 proteins, which is accompanied by severe disruption of desmosome as well as costamere architecture and composition in the heart

  8. Loss of desmoplakin expression and resultant disruption of desmosomal adhesion can promote increased local tumor invasion independent of adherens junction status.

  9. desmoplakin has a role in capillary formation

  10. desmocollins show a higher degree of similarity to the classical cadherins, such as E-cadherin (show CDH1 Antibodies), than to the desmogleins.

Human Desmoplakin (DSP) interaction partners

  1. Study reports a DSP mutation in an association with progressive cardiac conduction disease and a high risk of sudden death. The pathogenicity of the newly identified genetic variant was confirmed by in vitro prediction analysis and familial segregation. These results suggest that the effect of the mutation might be partially due to abnormal function of ion channels as a consequence of desmosomal remodeling.

  2. DSP is a desmosomal protein critical to cell-cell adhesion in a variety of cell types and important in wound healing and epithelial barrier function.

  3. Novel desmoplakin frameshift deletion p.Thr2625fs (c.7871_7872delAC) was identified as a potential cause of heart disease and sudden cardiac death in a Polish family.

  4. This is the first report of DSP genetic screening in Chinese sudden unexplained nocturnal death syndrome (SUNDS) and Brugada syndrome. Our results imply that DSP mutations contribute to the genetic cause of some SUNDS victims and maybe a new susceptible gene for Brugada syndrome.

  5. Syndrome featuring erythrokeratodermia and cardiomyopathy (EKC (show TAC4 Antibodies)) caused by mutation in DSP was described. Specific region of DSP protein critical to the pathobiology of EKC (show TAC4 Antibodies) syndrome and to DSP function in the heart and skin was identified.

  6. There is higher incidence of Myocarditis in DSP mutation carriers affected by Arrhythmogenic right ventricular dysplasia.

  7. Case Reports: desmoplakin mutations associated with variable woolly hair or hypotrichosis, palmoplantar keratoderma, and cardiac manifestations.

  8. Genetic testing revealed a novel combination of two heterozygous mutations in the DSP gene encoding desmoplakin

  9. Case Report: PKP2 (show PKP2 Antibodies)/DSP mutations in patient with Brugada syndrome and ventricular tachycardia.

  10. Patients whose MPM tissues expressed elevated mRNA levels of BIRC5 (show BIRC5 Antibodies), DSP, NME2, and THBS2 (show THBS2 Antibodies) showed a statistically significant shorter overall survival.

Desmoplakin (DSP) Antigen Profile

Antigen Summary

Desmosomes are intercellular junctions that tightly link adjacent cells. Desmoplakin is an obligate component of functional desmosomes that anchors intermediate filaments to desmosomal plaques. The N-terminus of desmoplakin is required for localization to the desmosome and interacts with the N-terminal region of plakophilin 1 and plakoglobin. The C-terminus of desmoplakin binds with intermediate filaments. In the mid-region of desmoplakin, a coiled-coiled rod domain is responsible for homodimerization. Mutations in this gene are the cause of several cardiomyopathies and keratodermas as well as the autoimmune disease paraneoplastic pemphigus.

Alternative names and synonyms associated with Desmoplakin (DSP)

  • desmoplakin (PhopGV104) antibody
  • desmoplakin (ORF-59 desmoplakin) antibody
  • Desmoplakin (desmop) antibody
  • desmoplakin (DSP) antibody
  • desmoplakin (dsp) antibody
  • putative desmoplakin (desmoplakin) antibody
  • desmoplakin (desmoplakin) antibody
  • desmoplakin a (dspa) antibody
  • ORF112 DESMOPLAKIN (orf112 desmoplakin) antibody
  • desmoplakin (ClgVgp102) antibody
  • desmoplakin (COGV_gp091) antibody
  • Desmoplakin (APNV_p087) antibody
  • desmoplakin (CBNV_gp066) antibody
  • desmoplakin (EONV_gp057) antibody
  • desmoplakin (OLNV_gp066) antibody
  • agip105 (AgipMNPV_gp105) antibody
  • desmoplakin (HaMNV_gp106) antibody
  • desmoplakin (EupsNPV_gp065) antibody
  • desmoplakin (PsunGV_gp139) antibody
  • expressed sequence AA589385 (AA589385) antibody
  • desmoplakin (ClanGV_gp096) antibody
  • desmoplakin (Dsp) antibody
  • wu:fi04e12 (wu:fi04e12) antibody
  • 2300002E22Rik antibody
  • 5730453H04Rik antibody
  • AA407887 antibody
  • AA407888 antibody
  • AW109828 antibody
  • DP antibody
  • DPI antibody
  • DPII antibody
  • DSP antibody
  • fi04e12 antibody
  • im:6911953 antibody
  • sb:cb570 antibody
  • wu:fc17a08 antibody
  • wu:fk73d01 antibody

Protein level used designations for anti-Desmoplakin (DSP) Antibodies

desmoplakin , Desmoplakin , putative desmoplakin , fk73d01 , ORF112 DESMOPLAKIN , agip105 , 250/210 kDa paraneoplastic pemphigus antigen , desmoplakin I , desmoplakin II , desmoplakin I/II , desmosomal cytoskeletal connector molecule , desmoplakin-related protein

GENE ID SPECIES
949289 Phthorimaea operculella granulovirus
3431549 Chrysodeixis chalcites nucleopolyhedrovirus
3890593 Hyphantria cunea nucleopolyhedrovirus
100061514 Equus caballus
694860 Macaca mulatta
462420 Pan troglodytes
779453 Xenopus (Silurana) tropicalis
951777 Mamestra configurata nucleopolyhedrovirus B
1463319 Adoxophyes orana granulovirus
324023 Danio rerio
921447 Cydia pomonella granulovirus
1725003 Cryptophlebia leucotreta granulovirus
4155920 Choristoneura occidentalis granulovirus
5141424 Antheraea pernyi nucleopolyhedrovirus
5141926 Clanis bilineata nucleopolyhedrovirus
5176508 Ectropis obliqua nucleopolyhedrovirus
5850536 Orgyia leucostigma NPV
6965873 Agrotis ipsilon multiple nucleopolyhedrovirus
7056761 Helicoverpa armigera multiple nucleopolyhedrovirus
7804620 Euproctis pseudoconspersa nucleopolyhedrovirus
8763999 Pseudaletia unipuncta granulovirus
100540 Mus musculus
10722977 Clostera anachoreta granulovirus
100027776 Monodelphis domestica
100083608 Ornithorhynchus anatinus
420869 Gallus gallus
1832 Homo sapiens
488207 Canis lupus familiaris
514360 Bos taurus
109620 Mus musculus
306871 Rattus norvegicus
398354 Xenopus laevis
100354434 Oryctolagus cuniculus
100721053 Cavia porcellus
101119169 Ovis aries
327364 Danio rerio
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