Browse our LILRB1 Proteins (LILRB1)

Full name:
Leukocyte Immunoglobulin-Like Receptor, Subfamily B (With TM and ITIM Domains), Member 1 Proteins (LILRB1)
On are 18 Leukocyte Immunoglobulin-Like Receptor, Subfamily B (With TM and ITIM Domains), Member 1 (LILRB1) Proteins from 10 different suppliers available. Additionally we are shipping LILRB1 Antibodies (107) and LILRB1 Kits (6) and many more products for this protein. A total of 137 LILRB1 products are currently listed.
CD85J, ILT-2, ILT2, LIR-1, LIR1, MIR-7, MIR7
list all proteins Gene Name GeneID UniProt
LILRB1 10859 Q8NHL6

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LILRB1 Proteins (LILRB1) by Origin

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Top referenced LILRB1 Proteins

  1. Human LILRB1 Protein expressed in HEK-293 Cells - ABIN2181470 : Cosman, Fanger, Borges, Kubin, Chin, Peterson, Hsu: A novel immunoglobulin superfamily receptor for cellular and viral MHC class I molecules. in Immunity 1997 (PubMed)
    Show all 4 references for 2181470

More Proteins for LILRB1 Interaction Partners

Human Leukocyte Immunoglobulin-Like Receptor, Subfamily B (With TM and ITIM Domains), Member 1 (LILRB1) interaction partners

  1. LILRB1 ligation during the differentiation of monocytes to dendritic cells in vitro results in increased ABIN1 (show TNIP1 Proteins) expression. ABIN1 (show TNIP1 Proteins) mediates the effects of LILRB1 ligation-induced inhibitory effects on immune responses.

  2. the results support that a regulated assembly of these noncanonical HLA-I conformers during the immune response may enhance the avidity of their interaction with LILRB1.

  3. miR7 negatively regulates PAK1 (show PAK1 Proteins) protein expression but has no effect on PAK1 (show PAK1 Proteins) mRNA expression. Knockdown of PAK1 (show PAK1 Proteins) expression markedly suppressed thyroid cancer cell proliferation, migration and invasion.

  4. this study shows that in the tuberculosis with pleural effusion -PE cases, ILT-2 expressing cells are reduced at the local disease site

  5. a woman's heterozygosity in HLA-G (show HLAG Proteins) and LILRB1 might be an advantage for a success of reproduction, but the partner's heterozygosity in 9A/10A KIR2DL4 (show KIR2DL4 Proteins) alleles might not

  6. Surprisingly, the ability of LIR1(+) natural killer cells to control virus spread differed between human cytomegalovirus strains, and this phenomenon was dependent on amino acid sequences within the viral ligand UL18.

  7. LIR-1 expression on CD8 (show CD8A Proteins)+ T cells in Rheumatoid Arthritis patients was higher than that in healthy controls.

  8. One SNP in LILRB1 (5724G>A) influenced the risk of NSCLC. 5724G>A was associated with protection from tumor cell infiltration of regional lymph nodes. Expression in tumor tissue correlated with tumor stage.

  9. Our findings offer new insights into the immunopathology of rheumatoid arthritis(RA) patients with long-lasting anti-RA-treatment and highlight the importance to also measure the binding capability of sHLA-G to LILRB1

  10. Data show that the leukocyte antigen (show HLADRB4 Proteins) G HLA-G (show HLAG Proteins) alpha1-alpha3 structure, which constitutes the extracellular part of HLA-G2 and HLA-G6, binds the immunologic receptor LILRB2 (show LILRB2 Proteins) but not LILRB1.

LILRB1 Protein Profile

Protein Summary

This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with LILRB1

  • leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1 (LILRB1)
  • CD85J protein
  • ILT-2 protein
  • ILT2 protein
  • LIR-1 protein
  • LIR1 protein
  • MIR-7 protein
  • MIR7 protein

Protein level used designations for LILRB1

CD85 antigen-like family member J , Ig-like transcript 2 , leukocyte immunoglobulin-like receptor subfamily B member 1 , leukocyte immunoglobulin-like receptor subfamily B member 1 soluble isoform , monocyte/macrophage immunoglobulin-like receptor 7

10859 Homo sapiens
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