LILRB1 Products
(Leukocyte Immunoglobulin-Like Receptor, Subfamily B (With TM and ITIM Domains), Member 1 (LILRB1))
Categories
This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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Featured LILRB1 Categories
LILRB1 Antibodies
High quality antibodies with extensive validation data.
LILRB1 ELISA Kits
Reliable ELISA kits for a wide range of species.
LILRB1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended LILRB1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, FACS, IP, Func
Validations
- (3)
- (3)
Cat. No.
ABIN1774726
Quantity
0.1 mg
Datasheet
Datasheet
Reactivity
Human
Application
WB, FACS, IP
Validations
- (3)
- (3)
Cat. No.
ABIN1774725
Quantity
0.1 mg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, FACS
Validations
- (4)
Cat. No.
ABIN7193404
Quantity
0.1 mg
Datasheet
Datasheet
Recommended LILRB1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6968282
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN4883443
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Semi-Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6386001
Quantity
96 tests
Datasheet
Datasheet
Recommended LILRB1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (5)
Cat. No.
ABIN7275164
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (4)
Cat. No.
ABIN7275185
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (4)
Cat. No.
ABIN7275168
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our LILRB1 products
: "Functionalization-dependent effects of cellulose nanofibrils on tolerogenic mechanisms of human dendritic cells." in: International journal of nanomedicine, Vol. 13, pp. 6941-6960, (2018) (PubMed).: "Leukocyte immunoglobulin-like receptor B1 is critical for antibody-dependent dengue." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 111, Issue 7, pp. 2722-7, (2014) (PubMed).
: "Human leukocyte antigen E contributes to protect tumor cells from lysis by natural killer cells." in: Neoplasia (New York, N.Y.), Vol. 13, Issue 9, pp. 822-30, (2011) (PubMed).
: "Identification of a new phenotype of tolerogenic human dendritic cells induced by fungal proteases from Aspergillus oryzae." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 186, Issue 7, pp. 3966-76, (2011) (PubMed).
: "Identification of IDO-positive and IDO-negative human dendritic cells after activation by various proinflammatory stimuli." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 186, Issue 12, pp. 6701-9, (2011) (PubMed).
: "The inhibitory Fc gamma IIb receptor dampens TLR4-mediated immune responses and is selectively up-regulated on dendritic cells from rheumatoid arthritis patients with quiescent disease." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 183, Issue 7, pp. 4509-20, (2009) (PubMed).
: "Evidence for HIV-associated B cell exhaustion in a dysfunctional memory B cell compartment in HIV-infected viremic individuals." in: The Journal of experimental medicine, Vol. 205, Issue 8, pp. 1797-805, (2008) (PubMed).
: "HLA-G1 co-expression boosts the HLA class I-mediated NK lysis inhibition." in: International immunology, Vol. 13, Issue 2, pp. 193-201, (2001) (PubMed).
: "Identification of the CD85 antigen as ILT2, an inhibitory MHC class I receptor of the immunoglobulin superfamily." in: Journal of leukocyte biology, Vol. 65, Issue 6, pp. 841-5, (1999) (PubMed).
: "A novel family of Ig-like receptors for HLA class I molecules that modulate function of lymphoid and myeloid cells." in: Journal of leukocyte biology, Vol. 66, Issue 3, pp. 375-81, (1999) (PubMed).
Synonyms and alternative names related to LILRB1
leukocyte immunoglobulin like receptor B1 (LILRB1), CD85J, ILT-2, ILT2, LIR-1, LIR1, MIR-7, MIR7Protein level used designations for LILRB1
- CD85 antigen-like family member J
- Ig-like transcript 2
- leukocyte immunoglobulin-like receptor subfamily B member 1
- leukocyte immunoglobulin-like receptor subfamily B member 1 soluble isoform
- monocyte/macrophage immunoglobulin-like receptor 7
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