anti-Human C3 antibody for Immunohistochemistry (Frozen Sections)

Recommended C3 Antibody (supplied by: Log in to see )

Antigen
Complement Component 3 (C3) Antibodies
  • C3
  • C3-1
  • sb:cb26
  • si:dkey-76b14.4
  • wu:fi34b03
  • wu:fj86e11
  • asp
  • cpamd1
  • AI255234
  • ASP
  • HSE-MSF
  • Plp
  • AHUS5
  • ARMD9
  • C3a
  • C3b
  • CPAMD1
  • C3d
  • c3
  • c3_D
  • complement component c3a
  • complement component 3
  • complement C3-like
  • complement component C3
  • endogenous retrovirus group K, member 13
  • c3a
  • C3
  • c3
  • LOC100060539
  • c3-1
  • ERVK-13
Epitope
AA 1611-1631
16
14
6
6
5
5
5
4
3
3
3
2
2
2
2
2
1
1
1
1
1
Reactivity
Cow (Bovine), Human, Mouse (Murine), Rat (Rattus)
278
77
63
15
9
7
7
4
4
1
1
1
Host
Rabbit
139
118
102
27
15
9
Clonality
Polyclonal
Conjugate
This C3 antibody is un-conjugated
33
31
21
6
5
5
4
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
1
1
1
Application
Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
211
195
73
72
67
57
55
49
45
38
38
32
11
5
5
4
3
2
1
1
1
1
1
1
1
1
1
Options
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Catalog No. ABIN681913
$ 307.45
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN111065 IHC (fro) WB Mouse IgG1 Log in to see H11 2
1 ABIN317012 EIA FACS IHC (fro) WB Mouse IgG2b Log in to see 013III-1-16 3
1 ABIN112153 EIA IHC (fro) WB Mouse IgG1 Log in to see H206 1
1 ABIN181106 EIA FACS IHC (fro) WB Mouse IgG1 Log in to see 10-02A 1
1 ABIN181129 EIA FACS IHC (fro) Mouse IgG1 Log in to see 053A-514-3-1-4 2
1 ABIN111064 EIA IHC (fro) WB Mouse IgG2b Log in to see H13 3
1 ABIN181107 EIA FACS IHC (fro) WB Mouse IgG1 Log in to see 053A-1149-3-1-4 (1003) 2
1 ABIN784157 EIA IHC (fro) IHC (p) Sheep IgG Log in to see Polyclonal
1 ABIN568570 DB EIA ID IHC (fro) IF IP WB Biotin Goat IgG Log in to see Polyclonal
1 ABIN568572 DB EIA ID IHC (fro) IF IP WB HRP Goat IgG Log in to see Polyclonal
1 ABIN568571 EIA ID IHC (fro) IF IP FITC Goat IgG Log in to see Polyclonal
1 ABIN568574 EIA ID IHC (fro) IF IP TRITC Goat IgG Log in to see Polyclonal
1 ABIN1106776 EIA IHC (fro) IHC (p) Mouse IgG2a Log in to see bH6 2
1 ABIN681922 IHC (fro) IHC (p) HRP Rabbit IgG AA 1611-1631 Log in to see Polyclonal
1 ABIN2477804 IHC (fro) FACS ELISA Mouse IgG1 Log in to see 053A-514-3-1-4 2
1 ABIN121477 IHC (fro) FITC Sheep Log in to see Polyclonal
1 ABIN681915 IHC (fro) IHC (p) Biotin Rabbit IgG AA 1611-1631 Log in to see Polyclonal
1 ABIN345336 ICC IHC (fro) WB Mouse IgG1 Log in to see H11
1 ABIN2477803 IHC (fro) FACS ELISA WB Mouse IgG1 Log in to see 053A-1149-3-1-4 (also known as 1003) 1
1 ABIN601080 IHC (fro) WB Mouse IgG1 Log in to see

Top referenced anti-C3 antibody for Immunohistochemistry (Frozen Sections)

Similar anti-C3 Antibodies

Application / Reactivity Human Mouse (Murine) Rat (Rattus) Cow (Bovine)
Immunofluorescence (fixed cells) (IF/ICC) 1 Antibodies 1 Antibodies 1 Antibodies
Cytometry by Time of Flight (CyTOF) 2 Antibodies
Simple Western (SimWes) 1 Antibodies 1 Antibodies
Western Blotting (WB) 126 Antibodies 53 Antibodies 21 Antibodies 1 Antibodies
Turbidimetry (TB) 3 Antibodies
Thin Layer Immunoassay (TIA) 1 Antibodies
Radioimmunoassay (RIA) 5 Antibodies
Radial Immunodiffusion (RID) 1 Antibodies
Immunoturbidimetry (IT) 1 Antibodies
Immunosubtraction (ISub) 1 Antibodies 1 Antibodies
Immunoprecipitation (IP) 15 Antibodies

General

Antigen Complement Component 3 (C3) Antibodies
Epitope AA 1611-1631
(16), (14), (6), (6), (5), (5), (5), (4), (3), (3), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1)
Reactivity Cow (Bovine), Human, Mouse (Murine), Rat (Rattus)
(278), (77), (63), (15), (9), (7), (7), (4), (4), (1), (1), (1)
Host Rabbit
(139), (118), (102), (27), (15), (9)
Clonality
Polyclonal
Conjugate This C3 antibody is un-conjugated
(33), (31), (21), (6), (5), (5), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1)
Application Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
(211), (195), (73), (72), (67), (57), (55), (49), (45), (38), (38), (32), (11), (5), (5), (4), (3), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Pubmed 2 references available
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Product Details anti-C3 Antibody

Target Details C3 Application Details Handling ProductDetails: References for anti-C3 antibody (ABIN681913) Images
Purification Purified by Protein A.
Immunogen KLH conjugated synthetic peptide derived from human Complement C3 alpha chain
Isotype IgG

Target Details C3

Product Details anti-C3 Antibody Application Details Handling ProductDetails: References for anti-C3 antibody (ABIN681913) Images back to top
Antigen
Alternative Name Complement C3 (C3 Antibody Abstract)
Background

C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates. Derived from proteolytic degradation of complement C3, C3a anaphylatoxin is a mediator of local inflammatory process. In chronic inflammation, acts as a chemoattractant for neutrophils (By similarity). It induces the contraction of smooth muscle, increases vascular permeability and causes histamine release from mast cells and basophilic leukocytes. C3-beta-c: Acts as a chemoattractant for neutrophils in chronic inflammation. Acylation stimulating protein: adipogenic hormone that stimulates triglyceride (TG) synthesis and glucose transport in adipocytes, regulating fat storage and playing a role in postprandial TG clearance. Appears to stimulate TG synthesis via activation of the PLC, MAPK and AKT signaling pathways. Ligand for C5AR2. Promotes the phosphorylation, ARRB2-mediated internalization and recycling of C5AR2 (PubMed:837664, PubMed:29953, PubMed:959512, PubMed:1432298, PubMed:15833747, PubMed:16333141, PubMed:1961575).

Subcellular location: Secreted

Synonyms: ASP, C3a, C3b, AHUS5, ARMD9, CPAMD1, HEL-S-62p, Complement C3, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1, C3

Gene ID 718
UniProt P01024
Research Area Complement Factors
Pathways Complement System, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Regulation of G-Protein Coupled Receptor Protein Signaling

Application Details

Product Details anti-C3 Antibody Target Details C3 Handling ProductDetails: References for anti-C3 antibody (ABIN681913) Images back to top
Application Notes IHC-P 1:100-500
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
Restrictions For Research Use only

Handling

Product Details anti-C3 Antibody Target Details C3 Application Details ProductDetails: References for anti-C3 antibody (ABIN681913) Images back to top
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C
Expiry Date 12 months

ProductDetails: References for anti-C3 antibody (ABIN681913)

Product Details anti-C3 Antibody Target Details C3 Application Details Handling Images back to top
Product cited in:

Zhuang, Han, Li, Kienhöfer, Lee, Shumyak, Meyerholz, Rosadzinski, Rosner, Chan, Xu, Segal, Sobel, Yang, Hoffmann, Reeves: "A Novel Mechanism for Generating the Interferon Signature in Lupus: Opsonization of Dead Cells by Complement and IgM." in: Arthritis & rheumatology (Hoboken, N.J.), Vol. 68, Issue 12, pp. 2917-2928, 2016

Trang, Hirai, Nabeta, Fuke, Yamaguchi: "Membranoproliferative glomerulonephritis in a calf with nephrotic syndrome." in: Journal of comparative pathology, Vol. 151, Issue 2-3, pp. 162-5, 2014

Images

Product Details anti-C3 Antibody Target Details C3 Application Details Handling ProductDetails: References for anti-C3 antibody (ABIN681913) back to top
Supplier Images
Immunofluorescence (IF) image for anti-C3 antibody (Complement Component 3) (AA 1611-1631) (ABIN681913) Formalin-fixed and paraffin embedded rat liver labeled with Anti-C3 Polyclonal Antibo...
Immunofluorescence (IF) image for anti-C3 antibody (Complement Component 3) (AA 1611-1631) (ABIN681913) Formalin-fixed and paraffin embedded mouse kidney labeled with Anti-C3 Polyclonal Ant...
ELISA image for anti-C3 antibody (Complement Component 3) (AA 1611-1631) (ABIN681913) Antigen: 0.2 µg/100 µL Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:...