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anti-Human C3 antibody for Immunoprecipitation

Recommended C3 Antibody (supplied by: Log in to see )

Antigen
Complement Component 3 (C3) Antibodies
  • AHUS5
  • AI255234
  • ARMD9
  • asp
  • ASP
  • c3
  • C3
  • C3-1
  • C3a
  • C3b
  • C3d
  • c3_D
  • CPAMD1
  • cpamd1
  • HSE-MSF
  • Plp
  • sb:cb26
  • si:dkey-76b14.4
  • wu:fi34b03
  • wu:fj86e11
Reactivity
Human
242
65
55
18
13
5
5
5
3
2
1
Host
Rat
141
102
86
23
13
7
Clonality
Monoclonal
Conjugate
This C3 antibody is un-conjugated
34
31
20
6
6
5
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
2
2
1
Application
Enzyme Immunoassay (EIA), Immunoprecipitation (IP)
193
188
71
67
58
45
44
42
40
35
33
24
20
5
4
1
1
1
1
1
1
Supplier
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Catalog No. ABIN1107627
€ 518.57
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0008946119 ABIN1106774 IP Rat IgG2a Log in to see 4 3
0.0008946119 ABIN568570 DB EIA ID IHC (fro) IF IP WB Biotin Goat IgG Log in to see Polyclonal
0.0008946119 ABIN568574 EIA ID IHC (fro) IF IP TRITC Goat IgG Log in to see Polyclonal
0.0008946119 ABIN568571 EIA ID IHC (fro) IF IP FITC Goat IgG Log in to see Polyclonal
0.0008946119 ABIN568572 DB EIA ID IHC (fro) IF IP WB HRP Goat IgG Log in to see Polyclonal
0.0008946119 ABIN1106775 EIA IP Rat IgG2a Log in to see 3 4
0.0008946119 ABIN568573 ID IHC (p) IP Goat Log in to see Polyclonal
0.0008946119 ABIN200624 IP ELISA WB Mouse IgG1 C-Term Log in to see
0.0008946119 ABIN965475 FACS IP Lbl IHC ELISA WB Goat Log in to see
0.0008946119 ABIN784435 ID IP Rabbit Log in to see Polyclonal
0.0008946119 ABIN784434 ID IP Rabbit Log in to see Polyclonal
0.0008946119 ABIN784436 ID IHC (p) IP Rabbit Log in to see Polyclonal
0.0008946119 ABIN2192052 IA IP Rat Log in to see 3 2
0.0008946119 ABIN568575 ID IP Goat Log in to see Polyclonal
0.0008946119 ABIN4264514 ELISA IP Mouse IgG1 kappa Log in to see F1-8
0.0008946119 ABIN2215694 IP ELISA Rat IgG2a Log in to see 13A20

Top referenced anti-C3 antibody for Immunoprecipitation

Similar anti-C3 Antibodies

Application / Reactivity Human
Dot Blot (DB) 2 Antibodies
ELISA 119 Antibodies
Enzyme Immunoassay (EIA) 29 Antibodies
Flow Cytometry (FACS) 26 Antibodies
Immunoassay (IA) 5 Antibodies
Immunocytochemistry (ICC) 5 Antibodies
Immunodiffusion (ID) 12 Antibodies
Immunoelectrophoresis (IEP) 1 Antibodies
Immunofluorescence (IF) 7 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 33 Antibodies
Immunohistochemistry (IHC) 17 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 36 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 30 Antibodies
Immunoprecipitation (IP) 17 Antibodies
Immunoturbidimetry (IT) 1 Antibodies
Labeling (Lbl) 1 Antibodies
Radial Immunodiffusion (RID) 1 Antibodies
Radioimmunoassay (RIA) 4 Antibodies

General

Antigen Complement Component 3 (C3) Antibodies
Reactivity Human
(242), (65), (55), (18), (13), (5), (5), (5), (3), (2), (1)
Host Rat
(141), (102), (86), (23), (13), (7)
Clonality (Clone)
Monoclonal   ( )
Conjugate This C3 antibody is un-conjugated
(34), (31), (20), (6), (6), (5), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (1)
Application Enzyme Immunoassay (EIA), Immunoprecipitation (IP)
(193), (188), (71), (67), (58), (45), (44), (42), (40), (35), (33), (24), (20), (5), (4), (1), (1), (1), (1), (1), (1)
Pubmed 5 references available
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Product Details anti-C3 Antibody

Target Details C3 Application Details Handling References for anti-C3 Antibody (ABIN1107627) Images
Specificity The monocolonal antibody 9 reacts with a neoantigen on iC3, iC3b, C3dg and C3g. It recognizes iC3b, C3dg and C3g in plasma. The antibody does not recognize C3 or C3b.
Cross-Reactivity (Details) Species reactivity (tested):Human
Purification Protein G
Clone 9
Isotype IgG1

Target Details C3

Product Details anti-C3 Antibody Application Details Handling References for anti-C3 Antibody (ABIN1107627) Images back to top
Antigen
Alternative Name Complement C3 (C3 Antibody Abstract)
Background C3g itself however is a small fragment probably not formed in vivo. The complement system is an important factor in innate immunity. The third complement component, C3, is central to the classical, alternative and lectin pathways of complement activation. Activation products of the complement cascade contain neo-epitopes that are not present in the individual native components. The synthesis of C3 is tissue-specific and is modulated in response to a variety of stimulatory agents. C3 is the most abundant protein of the complement system with serum protein levels of about 1.3 mg/mL. An inherited deficiency of C3 predisposes the person to frequent bacterial infections. C3 fragments are deposited in tissues at sites of antibody-mediated immunopathology. In ulcerative colitis and idiopathic chronic inflammatory bowel disease, the deposition of C3 in the diseased mucosa has been reported. Proteolysis by C3-convertases results in the cleavage of C3 into C3a and C3b. C3b becomes attached to immune complexes and is further cleaved into iC3b and C3f. iC3b is further processed into C3c and C3dg. C3dg can be cleaved into C3d and C3g though this does not occur in plasma.Synonyms: Complement C3
Gene ID 718
NCBI Accession NP_000055
UniProt P01024
Research Area Complement Factors
Pathways Complement System

Application Details

Product Details anti-C3 Antibody Target Details C3 Handling References for anti-C3 Antibody (ABIN1107627) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-C3 Antibody Target Details C3 Application Details References for anti-C3 Antibody (ABIN1107627) Images back to top
Concentration 0.1 mg/mL
Buffer PBS, 0.02 % sodium azide, 0.1 % bovine serum albumin
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment Store at 2 - 8 °C.

References for anti-C3 Antibody (ABIN1107627)

Product Details anti-C3 Antibody Target Details C3 Application Details Handling Images back to top
Background publications

Mollnes, Lachmann: "Activation of the third component of complement (C3) detected by a monoclonal anti-C3'g' neoantigen antibody in a one-step enzyme immunoassay." in: Journal of immunological methods, Vol. 101, Issue 2, pp. 201-7, 1987

Lachmann, Voak, Oldroyd, Downie, Bevan: "Use of monoclonal anti-C3 antibodies to characterise the fragments of C3 that are found on erythrocytes." in: Vox sanguinis, Vol. 45, Issue 5, pp. 367-72, 1983

Chaplin, Monroe, Lachmann: "Further studies of the C3g component of the alpha 2D fragment of human C3." in: Clinical and experimental immunology, Vol. 51, Issue 3, pp. 639-46, 1983

Lachmann, Pangburn, Oldroyd: "Breakdown of C3 after complement activation. Identification of a new fragment C3g, using monoclonal antibodies." in: The Journal of experimental medicine, Vol. 156, Issue 1, pp. 205-16, 1982

Lachmann, Oldroyd, Milstein, Wright: "Three rat monoclonal antibodies to human C3." in: Immunology, Vol. 41, Issue 3, pp. 503-15, 1981