anti-Human Complement Factor B antibody for Enzyme Immunoassay

Recommended Complement Factor B Antibody (supplied by: Log in to see )

Antigen
Complement Factor B (CFB) Antibodies
  • bf
  • Bf-1
  • Brre-Bf
  • zgc:114032
  • Bf
  • Sp152
  • bfb-A
  • Bf B
  • LOC397725
  • fc04c04
  • wu:fc04c04
  • bf/c2
  • CFB
  • AHUS4
  • BF
  • BFD
  • CFAB
  • FB
  • FBI12
  • GBG
  • H2-Bf
  • PBF2
  • AI195813
  • AI255840
  • B
  • C2
  • Fb
  • Da1-24
  • complement factor B
  • zgc:158446
  • ATP synthase, H+ transporting, mitochondrial Fo complex, subunit s (factor B)
  • complement factor B-like
  • CFB
  • cfb
  • Bf
  • bfb-A
  • LOC397725
  • zgc:158446
  • bf/c2
  • Atp5s
  • Cfb
  • LOC100355944
Epitope
Fragment Bb
17
10
10
8
6
6
5
5
5
5
5
5
3
3
2
2
1
1
1
1
1
1
1
1
Reactivity
Human
179
50
47
2
1
1
1
1
1
Host
Mouse
131
56
16
7
Clonality
Monoclonal
Conjugate
This Complement Factor B antibody is un-conjugated
22
17
9
4
4
2
2
1
1
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Western Blotting (WB)
140
124
54
29
25
20
16
13
12
11
9
6
6
5
4
3
2
1
1
Supplier
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Catalog No. ABIN181113
$ 577.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN317054 EIA FACS WB Mouse IgG2a Fragment Bb Log in to see 032B-22-1-X 1
1 ABIN181128 EIA Func FACS IHC (fro) WB Mouse IgG1 Fragment Ba Log in to see 014III-33-2-4-3 2
1 ABIN951644 EIA IHC (p) WB Rabbit Ig AA 474-504, Middle Region Log in to see Polyclonal
1 ABIN1106808 EIA IP WB Mouse IgG1 Log in to see M13-12 1
1 ABIN1106809 EIA IP WB Mouse IgG1 Log in to see M20-6 3
1 ABIN1106810 EIA IP WB Mouse IgG2a Log in to see P21-15 3
1 ABIN1106805 EIA Mouse IgG2b Log in to see KT21
1 ABIN1106804 EIA Mouse IgG1 Log in to see KT24
1 ABIN5565014 EIA RIA Biotin Rabbit AA 26-259 Log in to see Polyclonal
1 ABIN5565011 EIA RIA Rabbit AA 26-259 Log in to see Polyclonal
1 ABIN1803637 EIA RIA Biotin Rabbit IgG Log in to see Polyclonal
1 ABIN1803636 EIA RIA Rabbit IgG Log in to see Polyclonal

General

Antigen Complement Factor B (CFB) Antibodies
Epitope Fragment Bb
(17), (10), (10), (8), (6), (6), (5), (5), (5), (5), (5), (5), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human
(179), (50), (47), (2), (1), (1), (1), (1), (1)
Host Mouse
(131), (56), (16), (7)
Clonality (Clone)
Monoclonal   ( )
Conjugate This Complement Factor B antibody is un-conjugated
(22), (17), (9), (4), (4), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Enzyme Immunoassay (EIA), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Western Blotting (WB)
(140), (124), (54), (29), (25), (20), (16), (13), (12), (11), (9), (6), (6), (5), (4), (3), (2), (1), (1)
Pubmed 1 reference available
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Product Details anti-Complement Factor B Antibody

Target Details Complement Factor B Application Details Handling ProductDetails: References for anti-Complement Factor B antibody (ABIN181113) Images
Specificity This antibody recognises the Bb fragment of 90 kDa complement factor B, present in blood serum.
Characteristics Synonyms: Properdin factor B, C3/C5 convertase, PBF2, CFB, BF, BFD, Glycine-rich beta glycoprotein
Purification Affinity chromatography on Protein A
Immunogen Human factor B
Clone 10-09-14
Isotype IgG1

Target Details Complement Factor B

Product Details anti-Complement Factor B Antibody Application Details Handling ProductDetails: References for anti-Complement Factor B antibody (ABIN181113) Images back to top
Antigen
Alternative Name Complement Factor B (CFB Antibody Abstract)
Background C3b associates with complement factor B, inducing conformational change which enables complement factor D to cleave the N-terminal of complement factor B, the Ba subunit, leaving the 63 kDa Bb subunit associated with C3b and forming C3 convertase. Subunit Bb is involved in the proliferation of preactivated B lymphocytes. Conversely, Ba inhibits lymphocyte proliferation.Synonyms: BF, BFD, C3/C5 convertase, CFB, Glycine-rich beta glycoprotein, PBF2, Properdin factor B
Gene ID 629
UniProt P00751
Research Area Coagulation
Pathways Complement System, Proton Transport, Ribonucleoside Biosynthetic Process

Application Details

Product Details anti-Complement Factor B Antibody Target Details Complement Factor B Handling ProductDetails: References for anti-Complement Factor B antibody (ABIN181113) Images back to top
Application Notes ELISA: This antibody binds to both the Bb fragment and complement factor B so is notsuitable for all ELISA applications. Western Blot. Flow Cytometry. Immunohistochemistry on frozen sections. Recommended Positive Control: Kidney from post streptocial glomerlulonephritis patients.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-Complement Factor B Antibody Target Details Complement Factor B Application Details ProductDetails: References for anti-Complement Factor B antibody (ABIN181113) Images back to top
Concentration 1.0mg/mL
Buffer Borate buffered saline containing 0.09 % Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Expiry Date 12 months

ProductDetails: References for anti-Complement Factor B antibody (ABIN181113)

Product Details anti-Complement Factor B Antibody Target Details Complement Factor B Application Details Handling Images back to top
Background publications

Xu, Narayana, Volanakis: "Structural biology of the alternative pathway convertase." in: Immunological reviews, Vol. 180, pp. 123-35, 2001