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|Application / Reactivity||Human|
|Enzyme Immunoassay (EIA)||11 Antibodies|
|Flow Cytometry (FACS)||24 Antibodies|
|Functional Studies (Func)||6 Antibodies|
|Immunoassay (IA)||2 Antibodies|
|Immunocytochemistry (ICC)||4 Antibodies|
|Immunodiffusion (ID)||6 Antibodies|
|Immunoelectrophoresis (IEP)||1 Antibodies|
|Immunofluorescence (Paraffin-embedded Sections) (IF (p))||11 Antibodies|
|Immunohistochemistry (IHC)||24 Antibodies|
|Immunohistochemistry (Acetone-fixed) (IHC (af))||2 Antibodies|
|Immunohistochemistry (Frozen Sections) (IHC (fro))||15 Antibodies|
|Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))||18 Antibodies|
|Immunoprecipitation (IP)||10 Antibodies|
|Radioimmunoassay (RIA)||2 Antibodies|
|Western Blotting (WB)||99 Antibodies|
|Antigen||Complement Factor B (CFB) Antibodies|
|Epitope||Fragment Bb Alternatives|
|Conjugate||This Complement Factor B antibody is un-conjugated Alternatives|
Enzyme Immunoassay (EIA), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Western Blotting (WB)
|1 reference available|
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Product Details anti-Complement Factor B AntibodyTarget Details Complement Factor B Application Details Handling References for anti-Complement Factor B Antibody (ABIN181113) Images
|Specificity||This antibody recognises the Bb fragment of 90 kDa complement factor B, present in blood serum.|
|Characteristics||Synonyms: Properdin factor B, C3/C5 convertase, PBF2, CFB, BF, BFD, Glycine-rich beta glycoprotein|
|Purification||Affinity chromatography on Protein A|
|Immunogen||Human factor B|
Target Details Complement Factor BProduct Details anti-Complement Factor B Antibody Application Details Handling References for anti-Complement Factor B Antibody (ABIN181113) Images back to top
|Alternative Name||Complement Factor B (CFB Antibody Abstract)|
|Background||C3b associates with complement factor B, inducing conformational change which enables complement factor D to cleave the N-terminal of complement factor B, the Ba subunit, leaving the 63 kDa Bb subunit associated with C3b and forming C3 convertase. Subunit Bb is involved in the proliferation of preactivated B lymphocytes. Conversely, Ba inhibits lymphocyte proliferation.Synonyms: BF, BFD, C3/C5 convertase, CFB, Glycine-rich beta glycoprotein, PBF2, Properdin factor B|
Application DetailsProduct Details anti-Complement Factor B Antibody Target Details Complement Factor B Handling References for anti-Complement Factor B Antibody (ABIN181113) Images back to top
ELISA: This antibody binds to both the Bb fragment and complement factor B so is notsuitable for all ELISA applications. Western Blot. Flow Cytometry. Immunohistochemistry on frozen sections. Recommended Positive Control: Kidney from post streptocial glomerlulonephritis patients.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
|Restrictions||For Research Use only|
HandlingProduct Details anti-Complement Factor B Antibody Target Details Complement Factor B Application Details References for anti-Complement Factor B Antibody (ABIN181113) Images back to top
|Buffer||Borate buffered saline containing 0.09 % Sodium Azide|
|Precaution of Use||This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Storage||4 °C/-20 °C|
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
|Expiry Date||12 months|
References for anti-Complement Factor B Antibody (ABIN181113)Product Details anti-Complement Factor B Antibody Target Details Complement Factor B Application Details Handling Images back to top
Xu, Narayana, Volanakis: "Structural biology of the alternative pathway convertase." in: Immunological reviews, Vol. 180, pp. 123-35, 2001