Browse our Complement Factor I (CFI) ELISA Kits

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Complement Factor I ELISA Kits (CFI)
On are 36 Complement Factor I (CFI) ELISA Kits from 12 different suppliers available. Additionally we are shipping Complement Factor I Antibodies (139) and Complement Factor I Proteins (17) and many more products for this protein. A total of 197 Complement Factor I products are currently listed.
AHUS3, C3b-INA, c3bc4bi, C3BINA, CFI, factor I, FI, gb:ai721528, IF, KAF, MGC53615

Top referenced Complement Factor I ELISA Kits

  1. Human Complement Factor I ELISA Kit for Sandwich ELISA - ABIN415156 : Peyvandi, Rossio, Ferrari, Lotta, Pontiggia, Ghiringhelli Borsa, Pizzuti, Donadelli, Piras, Cugno, Noris: Thrombotic microangiopathy without renal involvement: two novel mutations in complement-regulator genes. in Journal of thrombosis and haemostasis : JTH 2016 (PubMed)
    Show all 2 references for 415156

More ELISA Kits for Complement Factor I Interaction Partners

Mouse (Murine) Complement Factor I (CFI) interaction partners

  1. Factor I-mediated generation of activated C3 fragments in the circulation is a critical determinant for the development of MPGN2 associated with factor H (show CFH ELISA Kits) deficiency.

Human Complement Factor I (CFI) interaction partners

  1. Factor I binds C3b-Factor H (show CFH ELISA Kits) between Factor H (show CFH ELISA Kits) domains 2 and 3 and a reoriented C3b C-terminal domain and docks onto the first scissile bond, while stabilizing its catalytic domain for proteolytic activity.

  2. Taken together, our data argue that multiple rare and ultra-rare alleles in CFI contribute to AMD (show AMD1 ELISA Kits) pathogenesis; they improve the precision of the assessment of the contribution of CFI to AMD (show AMD1 ELISA Kits)

  3. Case Report: thrombotic microangiopathy with mutations in complement factor I and thrombomodulin (show THBD ELISA Kits).

  4. Our results indicate that CFI polymorphisms are not significantly associated with VKH syndrome.

  5. Patients with advanced atrophic AMD (show AMD1 ELISA Kits) carried these rare variants more frequently than patients with neovascular AMD (show AMD1 ELISA Kits) (11 of 93 [11.8%] vs 40 of 835 [4.8%]; P = .04).

  6. Low FI levels are strongly associated with rare CFI variants and age-related macular degeneration.

  7. A missense variant (p.V412M) in CFI was discovered in two Tunisian Jewish families with early-onset age-related macular degeneration.

  8. Regulatory components of the alternative complement pathway in endothelial cell cytoplasm, factor H (show CFH ELISA Kits) and factor I, are not packaged in Weibel-Palade bodies.

  9. In this study, the odds of AMD (show AMD1 ELISA Kits) were highest in those with deficient vitamin D status and 2 risk alleles for the CFH (show CFH ELISA Kits) and CFI genotypes, suggesting a synergistic effect between vitamin D status and complement cascade protein function.

  10. association between rs10033900 and age-related macular degeneration risk in Han Chinese population

Complement Factor I (CFI) Antigen Profile

Antigen Summary

This gene encodes a serine proteinase that is essential for regulating the complement cascade. The encoded preproprotein is cleaved to produce both heavy and light chains, which are linked by disulfide bonds to form a heterodimeric glycoprotein. This heterodimer can cleave and inactivate the complement components C4b and C3b, and it prevents the assembly of the C3 and C5 convertase enzymes. Defects in this gene cause complement factor I deficiency, an autosomal recessive disease associated with a susceptibility to pyogenic infections. Mutations in this gene have been associated with a predisposition to atypical hemolytic uraemic syndrome, a disease characterized by acute renal failure, microangiopathic hemolytic anemia and thrombocytopenia. Primary glomerulonephritis with immmune deposits is another condition associated with mutation of this gene.

Alternative names and synonyms associated with Complement Factor I (CFI)

  • complement factor I (cfi) Elisa Kit
  • Factor I C3b/C4b inactivator (serine protease) (Cfi) Elisa Kit
  • complement factor I (CFI) Elisa Kit
  • complement component factor i (Cfi) Elisa Kit
  • complement factor I (Cfi) Elisa Kit
  • complement factor I-like (LOC100516921) Elisa Kit
  • AHUS3 Elisa Kit
  • C3b-INA Elisa Kit
  • c3bc4bi Elisa Kit
  • C3BINA Elisa Kit
  • CFI Elisa Kit
  • factor I Elisa Kit
  • FI Elisa Kit
  • gb:ai721528 Elisa Kit
  • IF Elisa Kit
  • KAF Elisa Kit
  • MGC53615 Elisa Kit

Protein level used designations for Complement Factor I (CFI) ELISA Kits

complement factor I , I factor (complement) , complement factor 1 , C3B/C4B inactivator , C3b-inactivator , Konglutinogen-activating factor , complement component I , complement control protein factor I , complement factor I heavy chain , light chain of factor I , complement component 1

379108 Xenopus laevis
399318 Xenopus laevis
471271 Pan troglodytes
557557 Danio rerio
613100 Xenopus (Silurana) tropicalis
100072852 Equus caballus
100306949 Ictalurus punctatus
12630 Mus musculus
3426 Homo sapiens
79126 Rattus norvegicus
100338923 Oryctolagus cuniculus
100713918 Cavia porcellus
513197 Bos taurus
478515 Canis lupus familiaris
428773 Gallus gallus
101119307 Ovis aries
100174703 Pongo abelii
100516921 Sus scrofa
Selected quality suppliers for Complement Factor I (CFI) ELISA Kits
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