anti-Human Coagulation Factor XII (Hageman Factor) antibody for Immunofluorescence (Paraffin-embedded Sections)

Recommended Coagulation Factor XII (Hageman Factor) Antibody (supplied by: Log in to see )

Antigen
Coagulation Factor XII (Hageman Factor) (F12) Antibodies
  • HAE3
  • HAEX
  • HAF
  • FXII
  • coagulation factor XII (Hageman factor)
  • F12
Reactivity
Human, Mouse (Murine), Rat (Rattus)
154
33
28
2
1
Host
Rabbit
90
30
24
18
1
Clonality
Polyclonal
Conjugate
Un-conjugated
12
9
8
4
4
4
1
1
1
1
1
1
1
1
1
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
108
88
21
20
10
9
9
5
5
4
4
2
2
2
2
2
1
1
1
Options
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

Submit your validation data for this product and get a full refund. I want to validate this product

Learn more

Available images

Catalog No. ABIN1387090
$ 295.90
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN2813027 IF (p) Alexa Fluor 594 Rabbit IgG Heavy Chain Log in to see Polyclonal
1 ABIN1420970 IF (p) Cy7 Rabbit IgG Log in to see Polyclonal
1 ABIN1403097 IF (p) Alexa Fluor 350 Rabbit IgG Log in to see Polyclonal
1 ABIN1403098 IF (p) Alexa Fluor 488 Rabbit IgG Log in to see Polyclonal
1 ABIN1403099 IF (p) Alexa Fluor 555 Rabbit IgG Log in to see Polyclonal
1 ABIN1403100 IF (p) Alexa Fluor 647 Rabbit IgG Log in to see Polyclonal
1 ABIN1403102 IF (p) FITC Rabbit IgG Log in to see Polyclonal
1 ABIN1420968 IF (p) Cy5 Rabbit IgG Log in to see Polyclonal
1 ABIN1420969 IF (p) Cy5.5 Rabbit IgG Log in to see Polyclonal
1 ABIN1420967 IF (p) Cy3 Rabbit IgG Log in to see Polyclonal

General

Antigen Coagulation Factor XII (Hageman Factor) (F12) Antibodies
Reactivity Human, Mouse (Murine), Rat (Rattus)
(154), (33), (28), (2), (1)
Host Rabbit
(90), (30), (24), (18), (1)
Clonality
Polyclonal
Conjugate Un-conjugated
(12), (9), (8), (4), (4), (4), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
(108), (88), (21), (20), (10), (9), (9), (5), (5), (4), (4), (2), (2), (2), (2), (2), (1), (1), (1)
Supplier Log in to see

Product details

Target details Application Details Handling Images
Purification Purified by Protein A.
Immunogen KLH conjugated synthetic peptide derived from human Coagulation factor XIIa heavy chain
Isotype IgG

Target details

Product details Application Details Handling Images back to top
Antigen
Alternative Name Factor XII (F12 Antibody Abstract)
Background

This gene encodes coagulation factor XII which circulates in blood as a zymogen. This single chain zymogen is converted to a two-chain serine protease with an heavy chain (alpha-factor XIIa) and a light chain. The heavy chain contains two fibronectin-type domains, two epidermal growth factor (EGF)-like domains, a kringle domain and a proline-rich domain, whereas the light chain contains only a catalytic domain. On activation, further cleavages takes place in the heavy chain, resulting in the production of beta-factor XIIa light chain and the alpha-factor XIIa light chain becomes beta-factor XIIa heavy chain. Prekallikrein is cleaved by factor XII to form kallikrein, which then cleaves factor XII first to alpha-factor XIIa and then to beta-factor XIIa. The active factor XIIa participates in the initiation of blood coagulation, fibrinolysis, and the generation of bradykinin and angiotensin. It activates coagulation factors VII and XI. Defects in this gene do not cause any clinical symptoms and the sole effect is that whole-blood clotting time is prolonged. [provided by RefSeq, Jul 2008].

Synonyms: Factor XII, Coagulation factor XII, Factor XII heavy chain, Coagulation factor XIIa heavy chain, F12, F12 deficiency, FA12_HUMAN, Factor XII deficiency, HAE3, HAEX, HAF, HAF deficiency, Hageman factor, Coagulation factor XIIa heavy chain.

Gene ID 2161
Pathways Complement System

Application Details

Product details Target details Handling Images back to top
Application Notes IHC-P 1:100-500
IF(IHC-P) 1:50-200
Restrictions For Research Use only

Handling

Product details Target details Application Details Images back to top
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C
Expiry Date 12 months

Images

Product details Target details Application Details Handling back to top
Supplier Images
Western Blotting (WB) image for anti-Coagulation Factor XII (Hageman Factor) (F12) antibody (ABIN1387090) Human HepG2 cells probed with Factor XII heavy chain Polyclonal Antibody, unconjugate...
Western Blotting (WB) image for anti-Coagulation Factor XII (Hageman Factor) (F12) antibody (ABIN1387090) Human 293T cells probed with Factor XII heavy chain Polyclonal Antibody, unconjugated...